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Intracellular BMP signaling regulation in vertebrates: pathway or network?
von Bubnoff A, Cho KW. von Bubnoff A, et al. Dev Biol. 2001 Nov 1;239(1):1-14. doi: 10.1006/dbio.2001.0388. Dev Biol. 2001. PMID: 11784015 Review.
Tob proteins enhance inhibitory Smad-receptor interactions to repress BMP signaling.
Yoshida Y, von Bubnoff A, Ikematsu N, Blitz IL, Tsuzuku JK, Yoshida EH, Umemori H, Miyazono K, Yamamoto T, Cho KW. Yoshida Y, et al. Among authors: von bubnoff a. Mech Dev. 2003 May;120(5):629-37. doi: 10.1016/s0925-4773(03)00020-0. Mech Dev. 2003. PMID: 12782279
A yeast two-hybrid screen identified Smad6 as a protein interacting with Tob. Tob co-localizes with Smad6 at the plasma membrane and enhances the interaction between Smad6 and activated BMP type I receptors. ...
A yeast two-hybrid screen identified Smad6 as a protein interacting with Tob. Tob co-localizes with Smad6 at the plasma membra
A Xenopus DNA microarray approach to identify novel direct BMP target genes involved in early embryonic development.
Peiffer DA, Von Bubnoff A, Shin Y, Kitayama A, Mochii M, Ueno N, Cho KW. Peiffer DA, et al. Among authors: von bubnoff a. Dev Dyn. 2005 Feb;232(2):445-56. doi: 10.1002/dvdy.20230. Dev Dyn. 2005. PMID: 15614776
Although BMPs are involved in a wide range of developmental and physiological functions, very few vertebrate target genes in this pathway have been identified. ...The finding reinforces the notion that BMP signals play important roles in a variety of biological proc …
Although BMPs are involved in a wide range of developmental and physiological functions, very few vertebrate target genes in this pat …
Phylogenetic footprinting and genome scanning identify vertebrate BMP response elements and new target genes.
von Bubnoff A, Peiffer DA, Blitz IL, Hayata T, Ogata S, Zeng Q, Trunnell M, Cho KW. von Bubnoff A, et al. Dev Biol. 2005 May 15;281(2):210-26. doi: 10.1016/j.ydbio.2005.02.014. Dev Biol. 2005. PMID: 15893974
A comparison between the Xenopus and human Vent2 promoter sequences revealed a highly conserved 21 bp sequence that overlaps the previously reported Xvent2 BMP response element (BRE). ...Comparison of the Xvent2 and the XId3 BRE revealed core sequence features that
A comparison between the Xenopus and human Vent2 promoter sequences revealed a highly conserved 21 bp sequence that overlaps t
The Xenopus laevis homeobox gene Xgbx-2 is an early marker of anteroposterior patterning in the ectoderm.
von Bubnoff A, Schmidt JE, Kimelman D. von Bubnoff A, et al. Mech Dev. 1996 Feb;54(2):149-60. doi: 10.1016/0925-4773(95)00468-8. Mech Dev. 1996. PMID: 8652408
In a search for homeobox genes expressed during early Xenopus development, we have isolated a gene which appears to be the Xenopus cognate of the mouse Gbx-2 gene. Expression of Xgbx-2 is first detectable by in situ hybridization at the midgastrula stage when it is …
In a search for homeobox genes expressed during early Xenopus development, we have isolated a gene which appears to be the Xen …
Seeking new antibiotics in nature's backyard.
von Bubnoff A. von Bubnoff A. Cell. 2006 Dec 1;127(5):867-9. doi: 10.1016/j.cell.2006.11.021. Cell. 2006. PMID: 17129770
As the pipeline of new antibiotics slows to a trickle, scientists are developing innovative strategies to unearth antibacterial compounds in unexpected places....
As the pipeline of new antibiotics slows to a trickle, scientists are developing innovative strategies to unearth antibacterial compo …
Superpostdocs reach for the stars.
von Bubnoff A. von Bubnoff A. Cell. 2007 Mar 23;128(6):1023-6. doi: 10.1016/j.cell.2007.03.005. Cell. 2007. PMID: 17382872
In the US and now also in Europe, a growing number of special fellowship programs, sometimes called "superpostdocs," offer newly minted PhDs instant independence and enable them to undertake pioneering research. ...
In the US and now also in Europe, a growing number of special fellowship programs, sometimes called "superpostdocs," offer newly mint …
Next-generation sequencing: the race is on.
von Bubnoff A. von Bubnoff A. Cell. 2008 Mar 7;132(5):721-3. doi: 10.1016/j.cell.2008.02.028. Cell. 2008. PMID: 18329356
PAVEing the way to a smaller trial.
von Bubnoff A. von Bubnoff A. IAVI Rep. 2008 Jul-Aug;12(4):1, 5-6. IAVI Rep. 2008. PMID: 20217937 No abstract available.
Interfering with HIV.
von Bubnoff A. von Bubnoff A. IAVI Rep. 2006 Sep-Oct;10(5):1-5. IAVI Rep. 2006. PMID: 20214237 No abstract available.
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