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Vitamin D controls T cell antigen receptor signaling and activation of human T cells.
von Essen MR, Kongsbak M, Schjerling P, Olgaard K, Odum N, Geisler C. von Essen MR, et al. Nat Immunol. 2010 Apr;11(4):344-9. doi: 10.1038/ni.1851. Epub 2010 Mar 7. Nat Immunol. 2010. PMID: 20208539
T-cell mean telomere lengths changes in treatment naïve HIV-infected patients randomized to G-CSF or placebo simultaneously with initiation of HAART.
Aladdin H, Von Essen M, Schjerling P, Katzenstein T, Gerstoft J, Skinhøj P, Klarlund Pedersen B, Ullum H. Aladdin H, et al. Scand J Immunol. 2001 Sep;54(3):301-5. doi: 10.1046/j.1365-3083.2001.00935.x. Scand J Immunol. 2001. PMID: 11555394 Clinical Trial.
Endo- and exocytic rate constants for spontaneous and protein kinase C-activated T cell receptor cycling.
Menné C, Møller Sørensen T, Siersma V, von Essen M, Ødum N, Geisler C. Menné C, et al. Eur J Immunol. 2002 Mar;32(3):616-26. doi: 10.1002/1521-4141(200203)32:3<616::aid-immu616>3.3.co;2-0. Eur J Immunol. 2002. PMID: 11857335
The CD3 gamma leucine-based receptor-sorting motif is required for efficient ligand-mediated TCR down-regulation.
von Essen M, Menné C, Nielsen BL, Lauritsen JP, Dietrich J, Andersen PS, Karjalainen K, Ødum N, Geisler C. von Essen M, et al. J Immunol. 2002 May 1;168(9):4519-23. doi: 10.4049/jimmunol.168.9.4519. J Immunol. 2002. PMID: 11970997
Ligand-induced TCR down-regulation is not dependent on constitutive TCR cycling.
Dietrich J, Menné C, Lauritsen JP, von Essen M, Rasmussen AB, Ødum N, Geisler C. Dietrich J, et al. J Immunol. 2002 Jun 1;168(11):5434-40. doi: 10.4049/jimmunol.168.11.5434. J Immunol. 2002. PMID: 12023336
TCR comodulation of nonengaged TCR takes place by a protein kinase C and CD3 gamma di-leucine-based motif-dependent mechanism.
Bonefeld CM, Rasmussen AB, Lauritsen JP, von Essen M, Ødum N, Andersen PS, Geisler C. Bonefeld CM, et al. J Immunol. 2003 Sep 15;171(6):3003-9. doi: 10.4049/jimmunol.171.6.3003. J Immunol. 2003. PMID: 12960325
Proteasomal targeting and minigene repetition improve cell-surface presentation of a transfected, modified melanoma tumour antigen.
Rasmussen AB, Zocca MB, Bonefeld CM, von Essen M, Lauritsen JP, Tomra S, Ødum N, Geisler C. Rasmussen AB, et al. Scand J Immunol. 2004 Feb;59(2):220-7. doi: 10.1111/j.0300-9475.2004.01374.x. Scand J Immunol. 2004. PMID: 14871300
Constitutive and ligand-induced TCR degradation.
von Essen M, Bonefeld CM, Siersma V, Rasmussen AB, Lauritsen JP, Nielsen BL, Geisler C. von Essen M, et al. J Immunol. 2004 Jul 1;173(1):384-93. doi: 10.4049/jimmunol.173.1.384. J Immunol. 2004. PMID: 15210797
Masking of the CD3 gamma di-leucine-based motif by zeta is required for efficient T-cell receptor expression.
Lauritsen JP, Bonefeld CM, von Essen M, Nielsen MW, Rasmussen AB, Ødum N, Dietrich J, Geisler C. Lauritsen JP, et al. Traffic. 2004 Sep;5(9):672-84. doi: 10.1111/j.1600-0854.2004.00211.x. Traffic. 2004. PMID: 15296492
Protein kinase C (PKC) alpha and PKC theta are the major PKC isotypes involved in TCR down-regulation.
von Essen M, Nielsen MW, Bonefeld CM, Boding L, Larsen JM, Leitges M, Baier G, Odum N, Geisler C. von Essen M, et al. J Immunol. 2006 Jun 15;176(12):7502-10. doi: 10.4049/jimmunol.176.12.7502. J Immunol. 2006. PMID: 16751397
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