Betaine can eliminate the base pair composition dependence of DNA melting.
Rees WA, Yager TD, Korte J, von Hippel PH.
Rees WA, et al. Among authors: von hippel ph.
Biochemistry. 1993 Jan 12;32(1):137-44. doi: 10.1021/bi00052a019.
Biochemistry. 1993.
PMID: 8418834
We show that the amino acid analogue betaine shares with small tetraalkylammonium ions [Melchior, W. B., Jr., & von Hippel, P. H. (1973) Proc. Natl. Acad. Sci. U.S.A. 70, 298-302] the ability to reduce or even eliminate the base pair composition dependence of DN …
We show that the amino acid analogue betaine shares with small tetraalkylammonium ions [Melchior, W. B., Jr., & von Hippel …