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BRAF inhibition in refractory hairy-cell leukemia.
Dietrich S, Glimm H, Andrulis M, von Kalle C, Ho AD, Zenz T. Dietrich S, et al. Among authors: von kalle c. N Engl J Med. 2012 May 24;366(21):2038-40. doi: 10.1056/NEJMc1202124. N Engl J Med. 2012. PMID: 22621641 No abstract available.
A serious adverse event after successful gene therapy for X-linked severe combined immunodeficiency.
Hacein-Bey-Abina S, von Kalle C, Schmidt M, Le Deist F, Wulffraat N, McIntyre E, Radford I, Villeval JL, Fraser CC, Cavazzana-Calvo M, Fischer A. Hacein-Bey-Abina S, et al. Among authors: von kalle c. N Engl J Med. 2003 Jan 16;348(3):255-6. doi: 10.1056/NEJM200301163480314. N Engl J Med. 2003. PMID: 12529469 No abstract available.
Continued response off treatment after BRAF inhibition in refractory hairy cell leukemia.
Dietrich S, Hüllein J, Hundemer M, Lehners N, Jethwa A, Capper D, Acker T, Garvalov BK, Andrulis M, Blume C, Schulte C, Mandel T, Meissner J, Fröhling S, von Kalle C, Glimm H, Ho AD, Zenz T. Dietrich S, et al. Among authors: von kalle c. J Clin Oncol. 2013 Jul 1;31(19):e300-3. doi: 10.1200/JCO.2012.45.9495. Epub 2013 May 20. J Clin Oncol. 2013. PMID: 23690412 No abstract available.
BRAF inhibition in hairy cell leukemia with low-dose vemurafenib.
Dietrich S, Pircher A, Endris V, Peyrade F, Wendtner CM, Follows GA, Hüllein J, Jethwa A, Ellert E, Walther T, Liu X, Dyer MJ, Elter T, Brummer T, Zeiser R, Hermann M, Herold M, Weichert W, Dearden C, Haferlach T, Seiffert M, Hallek M, von Kalle C, Ho AD, Gaehler A, Andrulis M, Steurer M, Zenz T. Dietrich S, et al. Among authors: von kalle c. Blood. 2016 Jun 9;127(23):2847-55. doi: 10.1182/blood-2015-11-680074. Epub 2016 Mar 3. Blood. 2016. PMID: 26941398
Comprehensive genomic characterization of gene therapy-induced T-cell acute lymphoblastic leukemia.
Horak P, Uhrig S, Witzel M, Gil-Farina I, Hutter B, Rath T, Gieldon L, Balasubramanian GP, Pastor X, Heilig CE, Richter D, Schröck E, Ball CR, Brors B, Braun CJ, Albert MH, Scholl C, von Kalle C, Schmidt M, Fröhling S, Klein C, Glimm H. Horak P, et al. Among authors: von kalle c. Leukemia. 2020 Mar 3. doi: 10.1038/s41375-020-0779-z. Online ahead of print. Leukemia. 2020. PMID: 32127638 No abstract available.
Stem-cell gene therapy for the Wiskott-Aldrich syndrome.
Boztug K, Schmidt M, Schwarzer A, Banerjee PP, Díez IA, Dewey RA, Böhm M, Nowrouzi A, Ball CR, Glimm H, Naundorf S, Kühlcke K, Blasczyk R, Kondratenko I, Maródi L, Orange JS, von Kalle C, Klein C. Boztug K, et al. Among authors: von kalle c. N Engl J Med. 2010 Nov 11;363(20):1918-27. doi: 10.1056/NEJMoa1003548. N Engl J Med. 2010. PMID: 21067383 Free PMC article. Clinical Trial.
Increased gene transfer into human hematopoietic progenitor cells by extended in vitro exposure to a pseudotyped retroviral vector.
von Kalle C, Kiem HP, Goehle S, Darovsky B, Heimfeld S, Torok-Storb B, Storb R, Schuening FG. von Kalle C, et al. Blood. 1994 Nov 1;84(9):2890-7. Blood. 1994. PMID: 7524756
In 20 experiments, 1 x 10(6) marrow or peripheral blood mononuclear cells (PBMCs)/mL were exposed to identical titers of pseudotyped PG13/LN vector or PA317/LN vector in the presence of recombinant human interleukin-1 (IL-1), IL-3, IL-6, and stem cell factor (SCF; c-kit li …
In 20 experiments, 1 x 10(6) marrow or peripheral blood mononuclear cells (PBMCs)/mL were exposed to identical titers of pseudotyped PG13/LN …
Myelosuppressive conditioning improves autologous engraftment of genetically marked hematopoietic repopulating cells in dogs.
Barquinero J, Kiem HP, von Kalle C, Darovsky B, Goehle S, Graham T, Seidel K, Storb R, Schuening FG. Barquinero J, et al. Among authors: von kalle c. Blood. 1995 Mar 1;85(5):1195-201. Blood. 1995. PMID: 7532034
Nineteen dogs received either no conditioning (group A, n = 5), irradiation to both humeri with 1,000 cGy (group B, n = 5), a sublethal dose of cyclophosphamide 40 mg/kg (group C, n = 4), a sublethal dose of 200 or 300 cGy total body irradiation (TBI) (group D, n = 3), or …
Nineteen dogs received either no conditioning (group A, n = 5), irradiation to both humeri with 1,000 cGy (group B, n = 5), a sublethal dose …
Retrovirus-mediated gene transduction into canine peripheral blood repopulating cells.
Kiem HP, Darovsky B, von Kalle C, Goehle S, Stewart D, Graham T, Hackman R, Appelbaum FR, Deeg HJ, Miller AD, et al. Kiem HP, et al. Among authors: von kalle c. Blood. 1994 Mar 15;83(6):1467-73. Blood. 1994. PMID: 8123838
Peripheral blood mononuclear cells of a patient with advanced Hodgkin's lymphoma give rise to permanently growing Hodgkin-Reed Sternberg cells.
Wolf J, Kapp U, Bohlen H, Kornacker M, Schoch C, Stahl B, Mücke S, von Kalle C, Fonatsch C, Schaefer HE, Hansmann ML, Diehl V. Wolf J, et al. Among authors: von kalle c. Blood. 1996 Apr 15;87(8):3418-28. Blood. 1996. PMID: 8605360
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