von Kalle C - Search Results

1

GENE-IS: Time-Efficient and Accurate Analysis of Viral Integration Events in Large-Scale Gene Therapy Data.

Afzal S, Wilkening S, von Kalle C, Schmidt M, Fronza R. Afzal S, et al. Among authors: von kalle c. Mol Ther Nucleic Acids. 2017 Mar 17;6:133-139. doi: 10.1016/j.omtn.2016.12.001. Epub 2016 Dec 10. Mol Ther Nucleic Acids. 2017. PMID: 28325279 Free PMC article.

2

Bioinformatic clonality analysis of next-generation sequencing-derived viral vector integration sites.

Arens A, Appelt JU, Bartholomae CC, Gabriel R, Paruzynski A, Gustafson D, Cartier N, Aubourg P, Deichmann A, Glimm H, von Kalle C, Schmidt M. Arens A, et al. Among authors: von kalle c. Hum Gene Ther Methods. 2012 Apr;23(2):111-8. doi: 10.1089/hgtb.2011.219. Epub 2012 May 4. Hum Gene Ther Methods. 2012. PMID: 22559057 Free PMC article.

3

Integration of retroviral vectors.

Gabriel R, Schmidt M, von Kalle C. Gabriel R, et al. Among authors: von kalle c. Curr Opin Immunol. 2012 Oct;24(5):592-7. doi: 10.1016/j.coi.2012.08.006. Epub 2012 Sep 14. Curr Opin Immunol. 2012. PMID: 22981243 Review.

4

A largely random AAV integration profile after LPLD gene therapy.

Kaeppel C, Beattie SG, Fronza R, van Logtenstein R, Salmon F, Schmidt S, Wolf S, Nowrouzi A, Glimm H, von Kalle C, Petry H, Gaudet D, Schmidt M. Kaeppel C, et al. Among authors: von kalle c. Nat Med. 2013 Jul;19(7):889-91. doi: 10.1038/nm.3230. Epub 2013 Jun 16. Nat Med. 2013. PMID: 23770691

5

High-throughput monitoring of integration site clonality in preclinical and clinical gene therapy studies.

Giordano FA, Appelt JU, Link B, Gerdes S, Lehrer C, Scholz S, Paruzynski A, Roeder I, Wenz F, Glimm H, von Kalle C, Grez M, Schmidt M, Laufs S. Giordano FA, et al. Among authors: von kalle c. Mol Ther Methods Clin Dev. 2015 Apr 1;2:14061. doi: 10.1038/mtm.2014.61. eCollection 2015. Mol Ther Methods Clin Dev. 2015. PMID: 26052530 Free PMC article.

6

Lentiviral Vector Promoter is Decisive for Aberrant Transcript Formation.

Scholz SJ, Fronza R, Bartholomä CC, Cesana D, Montini E, von Kalle C, Gil-Farina I, Schmidt M. Scholz SJ, et al. Among authors: von kalle c. Hum Gene Ther. 2017 Oct;28(10):875-885. doi: 10.1089/hum.2017.162. Epub 2017 Aug 18. Hum Gene Ther. 2017. PMID: 28825370

7

Systematic comparative study of computational methods for T-cell receptor sequencing data analysis.

Afzal S, Gil-Farina I, Gabriel R, Ahmad S, von Kalle C, Schmidt M, Fronza R. Afzal S, et al. Among authors: von kalle c. Brief Bioinform. 2019 Jan 18;20(1):222-234. doi: 10.1093/bib/bbx111. Brief Bioinform. 2019. PMID: 29028876

8

Integration frequency and intermolecular recombination of rAAV vectors in non-human primate skeletal muscle and liver.

Nowrouzi A, Penaud-Budloo M, Kaeppel C, Appelt U, Le Guiner C, Moullier P, von Kalle C, Snyder RO, Schmidt M. Nowrouzi A, et al. Among authors: von kalle c. Mol Ther. 2012 Jun;20(6):1177-86. doi: 10.1038/mt.2012.47. Epub 2012 Mar 27. Mol Ther. 2012. PMID: 22453768 Free PMC article.

9

Detection of retroviral integration sites by linear amplification-mediated PCR and tracking of individual integration clones in different samples.

Schmidt M, Schwarzwaelder K, Bartholomae CC, Glimm H, von Kalle C. Schmidt M, et al. Among authors: von kalle c. Methods Mol Biol. 2009;506:363-72. doi: 10.1007/978-1-59745-409-4_24. Methods Mol Biol. 2009. PMID: 19110638

10

Comprehensive genomic access to vector integration in clinical gene therapy.

Gabriel R, Eckenberg R, Paruzynski A, Bartholomae CC, Nowrouzi A, Arens A, Howe SJ, Recchia A, Cattoglio C, Wang W, Faber K, Schwarzwaelder K, Kirsten R, Deichmann A, Ball CR, Balaggan KS, Yáñez-Muñoz RJ, Ali RR, Gaspar HB, Biasco L, Aiuti A, Cesana D, Montini E, Naldini L, Cohen-Haguenauer O, Mavilio F, Thrasher AJ, Glimm H, von Kalle C, Saurin W, Schmidt M. Gabriel R, et al. Among authors: von kalle c. Nat Med. 2009 Dec;15(12):1431-6. doi: 10.1038/nm.2057. Epub 2009 Nov 22. Nat Med. 2009. PMID: 19966782

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