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Single-cell atlas of ABCA7 loss-of-function reveals impaired neuronal respiration via choline-dependent lipid imbalances.
von Maydell D, Wright S, Bonner JM, Staab C, Spitaleri A, Liu L, Pao PC, Yu CJ, Scannail AN, Li M, Boix CA, Mathys H, Leclerc G, Menchaca GS, Welch G, Graziosi A, Leary N, Samaan G, Kellis M, Tsai LH. von Maydell D, et al. bioRxiv [Preprint]. 2024 Jun 28:2023.09.05.556135. doi: 10.1101/2023.09.05.556135. bioRxiv. 2024. PMID: 38979214 Free PMC article. Preprint.
PCR Allele Competitive Extension (PACE).
von Maydell D. von Maydell D. Methods Mol Biol. 2023;2638:263-271. doi: 10.1007/978-1-0716-3024-2_18. Methods Mol Biol. 2023. PMID: 36781648
APOE4 impairs myelination via cholesterol dysregulation in oligodendrocytes.
Blanchard JW, Akay LA, Davila-Velderrain J, von Maydell D, Mathys H, Davidson SM, Effenberger A, Chen CY, Maner-Smith K, Hajjar I, Ortlund EA, Bula M, Agbas E, Ng A, Jiang X, Kahn M, Blanco-Duque C, Lavoie N, Liu L, Reyes R, Lin YT, Ko T, R'Bibo L, Ralvenius WT, Bennett DA, Cam HP, Kellis M, Tsai LH. Blanchard JW, et al. Among authors: von maydell d. Nature. 2022 Nov;611(7937):769-779. doi: 10.1038/s41586-022-05439-w. Epub 2022 Nov 16. Nature. 2022. PMID: 36385529 Free PMC article.
Lipid accumulation induced by APOE4 impairs microglial surveillance of neuronal-network activity.
Victor MB, Leary N, Luna X, Meharena HS, Scannail AN, Bozzelli PL, Samaan G, Murdock MH, von Maydell D, Effenberger AH, Cerit O, Wen HL, Liu L, Welch G, Bonner M, Tsai LH. Victor MB, et al. Among authors: von maydell d. Cell Stem Cell. 2022 Aug 4;29(8):1197-1212.e8. doi: 10.1016/j.stem.2022.07.005. Cell Stem Cell. 2022. PMID: 35931030 Free PMC article.