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180 results
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Escitalopram (S-citalopram) and its metabolites in vitro: cytochromes mediating biotransformation, inhibitory effects, and comparison to R-citalopram.
von Moltke LL, Greenblatt DJ, Giancarlo GM, Granda BW, Harmatz JS, Shader RI. von Moltke LL, et al. Drug Metab Dispos. 2001 Aug;29(8):1102-9. Drug Metab Dispos. 2001. PMID: 11454728
Human cytochromes mediating sertraline biotransformation: seeking attribution.
Greenblatt DJ, von Moltke LL, Harmatz JS, Shader RI. Greenblatt DJ, et al. Among authors: von moltke ll. J Clin Psychopharmacol. 1999 Dec;19(6):489-93. doi: 10.1097/00004714-199912000-00001. J Clin Psychopharmacol. 1999. PMID: 10587282 No abstract available.
Nefazodone, meta-chlorophenylpiperazine, and their metabolites in vitro: cytochromes mediating transformation, and P450-3A4 inhibitory actions.
von Moltke LL, Greenblatt DJ, Granda BW, Grassi JM, Schmider J, Harmatz JS, Shader RI. von Moltke LL, et al. Psychopharmacology (Berl). 1999 Jul;145(1):113-22. doi: 10.1007/s002130051039. Psychopharmacology (Berl). 1999. PMID: 10445380
Diphenhydramine kinetics following intravenous, oral, and sublingual dimenhydrinate administration.
Scavone JM, Luna BG, Harmatz JS, von Moltke L, Greenblatt DJ. Scavone JM, et al. Biopharm Drug Dispos. 1990 Apr;11(3):185-9. doi: 10.1002/bdd.2510110302. Biopharm Drug Dispos. 1990. PMID: 2328304 Clinical Trial.
Sources of variability in ketoconazole inhibition of human cytochrome P450 3A in vitro.
Greenblatt DJ, Venkatakrishnan K, Harmatz JS, Parent SJ, von Moltke LL. Greenblatt DJ, et al. Among authors: von moltke ll. Xenobiotica. 2010 Oct;40(10):713-20. doi: 10.3109/00498254.2010.506224. Xenobiotica. 2010. PMID: 20712450 Review.
Fluvoxamine impairs single-dose caffeine clearance without altering caffeine pharmacodynamics.
Culm-Merdek KE, von Moltke LL, Harmatz JS, Greenblatt DJ. Culm-Merdek KE, et al. Among authors: von moltke ll. Br J Clin Pharmacol. 2005 Nov;60(5):486-93. doi: 10.1111/j.1365-2125.2005.02467.x. Br J Clin Pharmacol. 2005. PMID: 16236038 Free PMC article. Clinical Trial.
Interaction of flurbiprofen with cranberry juice, grape juice, tea, and fluconazole: in vitro and clinical studies.
Greenblatt DJ, von Moltke LL, Perloff ES, Luo Y, Harmatz JS, Zinny MA. Greenblatt DJ, et al. Among authors: von moltke ll. Clin Pharmacol Ther. 2006 Jan;79(1):125-33. doi: 10.1016/j.clpt.2005.09.014. Clin Pharmacol Ther. 2006. PMID: 16413247 Clinical Trial.
Atazanavir: effects on P-glycoprotein transport and CYP3A metabolism in vitro.
Perloff ES, Duan SX, Skolnik PR, Greenblatt DJ, von Moltke LL. Perloff ES, et al. Among authors: von moltke ll. Drug Metab Dispos. 2005 Jun;33(6):764-70. doi: 10.1124/dmd.104.002931. Epub 2005 Mar 11. Drug Metab Dispos. 2005. PMID: 15764714
Role of CYP3A and CYP2E1 in alcohol-mediated increases in acetaminophen hepatotoxicity: comparison of wild-type and Cyp2e1(-/-) mice.
Wolf KK, Wood SG, Allard JL, Hunt JA, Gorman N, Walton-Strong BW, Szakacs JG, Duan SX, Hao Q, Court MH, von Moltke LL, Greenblatt DJ, Kostrubsky V, Jeffery EH, Wrighton SA, Gonzalez FJ, Sinclair PR, Sinclair JF. Wolf KK, et al. Among authors: von moltke ll. Drug Metab Dispos. 2007 Jul;35(7):1223-31. doi: 10.1124/dmd.107.014738. Epub 2007 Mar 28. Drug Metab Dispos. 2007. PMID: 17392391
Role of NADPH-cytochrome P450 reductase and cytochrome-b5/NADH-b5 reductase in variability of CYP3A activity in human liver microsomes.
Gan L, von Moltke LL, Trepanier LA, Harmatz JS, Greenblatt DJ, Court MH. Gan L, et al. Among authors: von moltke ll. Drug Metab Dispos. 2009 Jan;37(1):90-6. doi: 10.1124/dmd.108.023424. Epub 2008 Oct 6. Drug Metab Dispos. 2009. PMID: 18838505 Free PMC article.
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