Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My Custom Filters

Edit custom filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1995 1
1996 1
1997 3
1998 2
1999 4
2000 2
2001 8
2002 8
2003 9
2004 10
2005 10
2006 13
2007 9
2008 13
2009 25
2010 26
2011 24
2012 28
2013 40
2014 36
2015 39
2016 42
2017 32
2018 26
2019 30
2020 47
2021 40
2022 47
2023 37
2024 40
2025 44
2026 22

Publication date

Text availability

Article attribute

Article type

Additional filters

Article Language

Species

Sex

Age

Other

Search Results

622 results

Results by year

Citations

3 articles found by citation matching
Show all

Search results

Filters applied: . Clear all
Page 1
Did you mean vulnerable plaque thin cap fibro atheroma (19 results)?
Vulnerable or High-Risk Plaque: A JACC: Cardiovascular Imaging Position Statement.
Vergallo R, Park SJ, Stone GW, Erlinge D, Porto I, Waksman R, Mintz GS, D'Ascenzo F, Seitun S, Saba L, Vliegenthart R, Alfonso F, Arbab-Zadeh A, Libby P, Di Carli MF, Muller JE, Maurer G, Gropler RJ, Chandrashekhar YS, Braunwald E, Fuster V, Jang IK. Vergallo R, et al. JACC Cardiovasc Imaging. 2025 Jun;18(6):709-740. doi: 10.1016/j.jcmg.2024.12.004. Epub 2025 Feb 26. JACC Cardiovasc Imaging. 2025. PMID: 40019413 Free article.
Thin-cap fibroatheroma, a plaque with a large lipidic core covered by a thin fibrous cap, is the prototype of the rupture-prone plaque and has been traditionally defined as "vulnerable plaque." ...Rather than the trad …
Thin-cap fibroatheroma, a plaque with a large lipidic core covered by a thin fibrous cap, is the p …
Mechanisms of plaque formation and rupture.
Bentzon JF, Otsuka F, Virmani R, Falk E. Bentzon JF, et al. Circ Res. 2014 Jun 6;114(12):1852-66. doi: 10.1161/CIRCRESAHA.114.302721. Circ Res. 2014. PMID: 24902970 Free article. Review.
The permissive structural requirement for this to occur is an extremely thin fibrous cap, and thus, ruptures occur mainly among lesions defined as thin-cap fibroatheromas. ...In this review, we discuss mechanisms of atherosclerotic pla …
The permissive structural requirement for this to occur is an extremely thin fibrous cap, and thus, ruptures occur mainly amon …
Pathology of the thin-cap fibroatheroma: a type of vulnerable plaque.
Virmani R, Burke AP, Kolodgie FD, Farb A. Virmani R, et al. J Interv Cardiol. 2003 Jun;16(3):267-72. doi: 10.1034/j.1600-0854.2003.8042.x. J Interv Cardiol. 2003. PMID: 12800406 Review.
Thin cap atheroma is the precursor of plaque rupture, which accounts for a majority of coronary thrombi. ...There is some evidence that a speckled pattern of calcification is associated with vulnerability to rupture. There are usually multiple thin …
Thin cap atheroma is the precursor of plaque rupture, which accounts for a majority of coronary thrombi. ...There is so …
The Role of Inflammation in Cardiovascular Disease.
Henein MY, Vancheri S, Longo G, Vancheri F. Henein MY, et al. Int J Mol Sci. 2022 Oct 26;23(21):12906. doi: 10.3390/ijms232112906. Int J Mol Sci. 2022. PMID: 36361701 Free PMC article. Review.
Macrophages catabolize the oxidized lipoproteins and coalesce into a lipid-rich necrotic core, encapsulated by a collagen fibrous cap, leading to the formation of fibro-atheroma. In the conditions of chronic inflammation, macrophages exert a catabolic effect on the fibrous …
Macrophages catabolize the oxidized lipoproteins and coalesce into a lipid-rich necrotic core, encapsulated by a collagen fibrous cap …
Pathology of the vulnerable plaque.
Virmani R, Burke AP, Farb A, Kolodgie FD. Virmani R, et al. J Am Coll Cardiol. 2006 Apr 18;47(8 Suppl):C13-8. doi: 10.1016/j.jacc.2005.10.065. J Am Coll Cardiol. 2006. PMID: 16631505 Free article.
The non-thrombosed lesion that most resembles the acute plaque rupture is the thin cap fibroatheroma (TCFA), which is characterized by a necrotic core with an overlying fibrous cap measuring <65 microm, containing rare smooth muscle cells but …
The non-thrombosed lesion that most resembles the acute plaque rupture is the thin cap fibroatheroma (TCFA), whi …
The thin-cap fibroatheroma: a type of vulnerable plaque: the major precursor lesion to acute coronary syndromes.
Kolodgie FD, Burke AP, Farb A, Gold HK, Yuan J, Narula J, Finn AV, Virmani R. Kolodgie FD, et al. Curr Opin Cardiol. 2001 Sep;16(5):285-92. doi: 10.1097/00001573-200109000-00006. Curr Opin Cardiol. 2001. PMID: 11584167 Review.
While the concept of plaque 'vulnerability' implies a propensity towards thrombosis, the term vulnerable was originally intended to provide a morphologic description consistent with plaques that are prone to rupture. ...The morphology, frequency, and p …
While the concept of plaque 'vulnerability' implies a propensity towards thrombosis, the term vulnerable was originally …
Coronary Artery Calcification: From Mechanism to Molecular Imaging.
Nakahara T, Dweck MR, Narula N, Pisapia D, Narula J, Strauss HW. Nakahara T, et al. JACC Cardiovasc Imaging. 2017 May;10(5):582-593. doi: 10.1016/j.jcmg.2017.03.005. JACC Cardiovasc Imaging. 2017. PMID: 28473100 Free article. Review.
The location, density, and confluence of calcification may change portions of the arterial conduit to a noncompliant structure. Calcifications may also seed the cap of a thin cap fibroatheroma, altering tensile forces on the cap and rendering th …
The location, density, and confluence of calcification may change portions of the arterial conduit to a noncompliant structure. Calcificatio …
Effect of Alirocumab Added to High-Intensity Statin Therapy on Coronary Atherosclerosis in Patients With Acute Myocardial Infarction: The PACMAN-AMI Randomized Clinical Trial.
Räber L, Ueki Y, Otsuka T, Losdat S, Häner JD, Lonborg J, Fahrni G, Iglesias JF, van Geuns RJ, Ondracek AS, Radu Juul Jensen MD, Zanchin C, Stortecky S, Spirk D, Siontis GCM, Saleh L, Matter CM, Daemen J, Mach F, Heg D, Windecker S, Engstrøm T, Lang IM, Koskinas KC; PACMAN-AMI collaborators. Räber L, et al. JAMA. 2022 May 10;327(18):1771-1781. doi: 10.1001/jama.2022.5218. JAMA. 2022. PMID: 35368058 Free PMC article. Clinical Trial.
IMPORTANCE: Coronary plaques that are prone to rupture and cause adverse cardiac events are characterized by large plaque burden, large lipid content, and thin fibrous caps. ...Two powered secondary end points were changes in near-infrared spectroscopy-derive …
IMPORTANCE: Coronary plaques that are prone to rupture and cause adverse cardiac events are characterized by large plaque burd …
Thin-cap fibroatheroma predicts clinical events in diabetic patients with normal fractional flow reserve: the COMBINE OCT-FFR trial.
Kedhi E, Berta B, Roleder T, Hermanides RS, Fabris E, IJsselmuiden AJJ, Kauer F, Alfonso F, von Birgelen C, Escaned J, Camaro C, Kennedy MW, Pereira B, Magro M, Nef H, Reith S, Al Nooryani A, Rivero F, Malinowski K, De Luca G, Garcia Garcia H, Granada JF, Wojakowski W. Kedhi E, et al. Eur Heart J. 2021 Dec 1;42(45):4671-4679. doi: 10.1093/eurheartj/ehab433. Eur Heart J. 2021. PMID: 34345911 Free article. Clinical Trial.
AIMS: The aim of this study was to understand the impact of optical coherence tomography (OCT)-detected thin-cap fibroatheroma (TCFA) on clinical outcomes of diabetes mellitus (DM) patients with fractional flow reserve (FFR)-negative lesions. ...This discrepa …
AIMS: The aim of this study was to understand the impact of optical coherence tomography (OCT)-detected thin-cap fibroather …
Thrombosis formation on atherosclerotic lesions and plaque rupture.
Badimon L, Vilahur G. Badimon L, et al. J Intern Med. 2014 Dec;276(6):618-32. doi: 10.1111/joim.12296. Epub 2014 Sep 25. J Intern Med. 2014. PMID: 25156650 Free article. Review.
The evolution of vascular disease involves a combination of endothelial dysfunction, extensive lipid deposition in the intima, exacerbated innate and adaptive immune responses, proliferation of vascular smooth muscle cells and remodelling of the extracellular matrix, resulting in …
The evolution of vascular disease involves a combination of endothelial dysfunction, extensive lipid deposition in the intima, exacerbated i …
622 results