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Page 1
Mediterranean diet and cardiovascular health: Teachings of the PREDIMED study.
Ros E, Martínez-González MA, Estruch R, Salas-Salvadó J, Fitó M, Martínez JA, Corella D. Ros E, et al. Adv Nutr. 2014 May 14;5(3):330S-6S. doi: 10.3945/an.113.005389. Print 2014 May. Adv Nutr. 2014. PMID: 24829485 Free PMC article. Review.
The PREDIMED (Prevencion con Dieta Mediterranea) study was designed to assess the long-term effects of the Mediterranean diet (MeDiet) without any energy restriction on incident cardiovascular disease (CVD) as a multicenter, randomized, primary prevention trial in individu …
The PREDIMED (Prevencion con Dieta Mediterranea) study was designed to assess the long-term effects of the Mediterranean diet (MeDiet …
An Energy-Reduced Mediterranean Diet, Physical Activity, and Body Composition: An Interim Subgroup Analysis of the PREDIMED-Plus Randomized Clinical Trial.
Konieczna J, Ruiz-Canela M, Galmes-Panades AM, Abete I, Babio N, Fiol M, Martín-Sánchez V, Estruch R, Vidal J, Buil-Cosiales P, García-Gavilán JF, Moñino M, Marcos-Delgado A, Casas R, Olbeyra R, Fitó M, Hu FB, Martínez-Gonzalez MÁ, Martínez JA, Romaguera D, Salas-Salvadó J. Konieczna J, et al. JAMA Netw Open. 2023 Oct 2;6(10):e2337994. doi: 10.1001/jamanetworkopen.2023.37994. JAMA Netw Open. 2023. PMID: 37851444 Free PMC article. Clinical Trial.
DESIGN, SETTING, AND PARTICIPANTS: The ongoing Prevencion con Dieta Mediterranea-Plus (PREDIMED-Plus) randomized clinical trial is designed to test the effect of the intervention on cardiovascular disease prevention after 8 years of follow-up. ...The trial reported herein …
DESIGN, SETTING, AND PARTICIPANTS: The ongoing Prevencion con Dieta Mediterranea-Plus (PREDIMED-Plus) randomized clinical trial is de …
Prevention of Type 2 Diabetes by Lifestyle Changes: A Systematic Review and Meta-Analysis.
Uusitupa M, Khan TA, Viguiliouk E, Kahleova H, Rivellese AA, Hermansen K, Pfeiffer A, Thanopoulou A, Salas-Salvadó J, Schwab U, Sievenpiper JL. Uusitupa M, et al. Nutrients. 2019 Nov 1;11(11):2611. doi: 10.3390/nu11112611. Nutrients. 2019. PMID: 31683759 Free PMC article.
Most of the trials aimed to reduce weight, increase physical activity, and apply a diet relatively low in saturated fat and high in fiber. The PREDIMED trial that did not meet eligibility criteria for inclusion in the meta-analysis was used in the final assessment of diet …
Most of the trials aimed to reduce weight, increase physical activity, and apply a diet relatively low in saturated fat and high in fiber. T …
Impact of α-Linolenic Acid, the Vegetable ω-3 Fatty Acid, on Cardiovascular Disease and Cognition.
Sala-Vila A, Fleming J, Kris-Etherton P, Ros E. Sala-Vila A, et al. Adv Nutr. 2022 Oct 2;13(5):1584-1602. doi: 10.1093/advances/nmac016. Adv Nutr. 2022. PMID: 35170723 Free PMC article.
There is increasing evidence for ALA largely based on its major food sources (i.e., walnuts and flaxseed); however, this lags behind our understanding of long-chain n-3 fatty acids. ...Three randomized controlled trials (RCTs) [AlphaOmega trial, Prevencion con Dieta Medite …
There is increasing evidence for ALA largely based on its major food sources (i.e., walnuts and flaxseed); however, this lags behind …
A 14-item Mediterranean diet assessment tool and obesity indexes among high-risk subjects: the PREDIMED trial.
Martínez-González MA, García-Arellano A, Toledo E, Salas-Salvadó J, Buil-Cosiales P, Corella D, Covas MI, Schröder H, Arós F, Gómez-Gracia E, Fiol M, Ruiz-Gutiérrez V, Lapetra J, Lamuela-Raventos RM, Serra-Majem L, Pintó X, Muñoz MA, Wärnberg J, Ros E, Estruch R; PREDIMED Study Investigators. Martínez-González MA, et al. PLoS One. 2012;7(8):e43134. doi: 10.1371/journal.pone.0043134. Epub 2012 Aug 14. PLoS One. 2012. PMID: 22905215 Free PMC article. Clinical Trial.
DESIGN: Cross-sectional assessment of all participants in the "PREvencion con DIeta MEDiterranea" (PREDIMED) trial. SUBJECTS: 7,447 participants (55-80 years, 57% women) free of cardiovascular disease, but with either type 2 diabetes or 3 cardiovascular risk factors. ...
DESIGN: Cross-sectional assessment of all participants in the "PREvencion con DIeta MEDiterranea" (PREDIMED) trial. SUBJECTS: 7,447 p …
Remnant Cholesterol, Not LDL Cholesterol, Is Associated With Incident Cardiovascular Disease.
Castañer O, Pintó X, Subirana I, Amor AJ, Ros E, Hernáez Á, Martínez-González MÁ, Corella D, Salas-Salvadó J, Estruch R, Lapetra J, Gómez-Gracia E, Alonso-Gomez AM, Fiol M, Serra-Majem L, Corbella E, Benaiges D, Sorli JV, Ruiz-Canela M, Babió N, Sierra LT, Ortega E, Fitó M. Castañer O, et al. J Am Coll Cardiol. 2020 Dec 8;76(23):2712-2724. doi: 10.1016/j.jacc.2020.10.008. J Am Coll Cardiol. 2020. PMID: 33272365 Free article. Clinical Trial.
METHODS: This study determined the baseline lipid profile and searched for major adverse cardiovascular events (MACEs) in the high-risk primary prevention PREDIMED (Prevencion con Dieta Mediterranea) trial population (mean age: 67 years; body mass index: 30 kg/m(2); 43% me …
METHODS: This study determined the baseline lipid profile and searched for major adverse cardiovascular events (MACEs) in the high-risk prim …
Yearly attained adherence to Mediterranean diet and incidence of diabetes in a large randomized trial.
Martínez-González MA, Montero P, Ruiz-Canela M, Toledo E, Estruch R, Gómez-Gracia E, Li J, Ros E, Arós F, Hernáez A, Corella D, Fiol M, Lapetra J, Serra-Majem L, Pintó X, Cofán M, Sorlí JV, Babio N, Márquez-Sandoval YF, Castañer O, Salas-Salvadó J. Martínez-González MA, et al. Cardiovasc Diabetol. 2023 Sep 29;22(1):262. doi: 10.1186/s12933-023-01994-2. Cardiovasc Diabetol. 2023. PMID: 37775736 Free PMC article. Clinical Trial.
In the context of a randomized trial of primary cardiovascular prevention, we assessed type 2 diabetes incidence according to yearly repeated measures of compliance with a nutritional intervention based on the traditional Mediterranean diet. METHODS: PREDIMED (''PREvencion …
In the context of a randomized trial of primary cardiovascular prevention, we assessed type 2 diabetes incidence according to yearly repeate …
A multi-metabolite signature robustly predicts long-term mortality in the PREDIMED trial and several US cohorts.
Fernández-Duval G, Razquin C, Wang F, Yun H, Hu J, Guasch-Ferré M, Rexrode K, Balasubramanian R, García-Gavilán J, Ruiz-Canela M, Clish CB, Corella D, Gómez-Gracia E, Fiol M, Estruch R, Lapetra J, Fitó M, Serra-Majem L, Ros E, Liang L, Dennis C, Asensio EM, Castañer O, Planes FJ, Salas-Salvadó J, Hu FB, Toledo E, Martínez-González MA. Fernández-Duval G, et al. Metabolism. 2025 Sep;170:156195. doi: 10.1016/j.metabol.2025.156195. Epub 2025 Mar 17. Metabolism. 2025. PMID: 40107652 Free PMC article. Clinical Trial.
In a long-term follow-up subsample (n = 1878) of the PREDIMED trial, among 337 candidate baseline plasma metabolites repeatedly assessed at baseline and after 1 year, 38 plasma metabolites were identified as predictors of all-cause mortality. ...The multi-metabolite signat …
In a long-term follow-up subsample (n = 1878) of the PREDIMED trial, among 337 candidate baseline plasma metabolites repeatedly asses …
Olive oil consumption, plasma metabolites, and risk of type 2 diabetes and cardiovascular disease.
García-Gavilán JF, Babio N, Toledo E, Semnani-Azad Z, Razquin C, Dennis C, Deik A, Corella D, Estruch R, Ros E, Fitó M, Arós F, Fiol M, Lapetra J, Lamuela-Raventos R, Clish C, Ruiz-Canela M, Martínez-González MÁ, Hu F, Salas-Salvadó J, Guasch-Ferré M. García-Gavilán JF, et al. Cardiovasc Diabetol. 2023 Dec 13;22(1):340. doi: 10.1186/s12933-023-02066-1. Cardiovasc Diabetol. 2023. PMID: 38093289 Free PMC article.
METHODS: The discovery population included 1837 participants at high cardiovascular risk from the PREvencion con DIeta MEDiterranea (PREDIMED) trial with available metabolomics data at baseline. Olive oil consumption was determined through food-frequency questionnaires (FF …
METHODS: The discovery population included 1837 participants at high cardiovascular risk from the PREvencion con DIeta MEDiterranea (PRED …
Urinary polyphenol signature of the Mediterranean diet is associated with lower cardiovascular disease risk: the PREDIMED trial.
Domínguez-López I, Galkina P, Fernández-Duval G, Pozzoli C, Razquin C, Jáuregui O, Salas-Salvadó J, Tojal-Sierra L, Fitó M, Corella D, Fiol M, Lapetra J, Gómez-Gracia E, Pintó X, Ruiz-Canela M, Castañer O, Liang L, Sun Q, Serra-Majem L, Ros E, Martínez-González MÁ, Estruch R, Hu FB, Lamuela-Raventós RM. Domínguez-López I, et al. BMC Med. 2025 Dec 18;24(1):42. doi: 10.1186/s12916-025-04587-w. BMC Med. 2025. PMID: 41408634 Free PMC article. Clinical Trial.
METHODS: In a case-cohort nested study within the PREDIMED trial, we measured 62 phenolic metabolites in spot urine by liquid chromatography-high-resolution mass spectrometry at baseline and after 1 year in 1180 individuals: 653 incident CVD cases (stroke, myocardial infar …
METHODS: In a case-cohort nested study within the PREDIMED trial, we measured 62 phenolic metabolites in spot urine by liquid chromat …
106 results