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2002 2
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2009 2
2011 1
2021 0
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Role of nuclear receptor signaling in platelets: antithrombotic effects of PPARbeta.
Ali FY, Davidson SJ, Moraes LA, Traves SL, Paul-Clark M, Bishop-Bailey D, Warner TD, Mitchell JA. Ali FY, et al. Among authors: warner td. FASEB J. 2006 Feb;20(2):326-8. doi: 10.1096/fj.05-4395fje. Epub 2005 Dec 20. FASEB J. 2006. PMID: 16368717
Peroxisome proliferator-activated receptors (PPARs) are nuclear receptors that heterodimerize with the retinoid X receptor and then modulate at the transcriptional level the function of many target genes. ...In the current study, we show that PPARbeta ligands simila …
Peroxisome proliferator-activated receptors (PPARs) are nuclear receptors that heterodimerize with the retinoid X receptor and …
The epoxygenases CYP2J2 activates the nuclear receptor PPARalpha in vitro and in vivo.
Wray JA, Sugden MC, Zeldin DC, Greenwood GK, Samsuddin S, Miller-Degraff L, Bradbury JA, Holness MJ, Warner TD, Bishop-Bailey D. Wray JA, et al. Among authors: warner td. PLoS One. 2009 Oct 12;4(10):e7421. doi: 10.1371/journal.pone.0007421. PLoS One. 2009. PMID: 19823578 Free PMC article.
BACKGROUND: Peroxisome proliferator-activated receptors (PPARs) are a family of three (PPARalpha, -beta/delta, and -gamma) nuclear receptors. In particular, PPARalpha is involved in regulation of fatty acid metabolism, cell growth and inflammation. ...
BACKGROUND: Peroxisome proliferator-activated receptors (PPARs) are a family of three (PPARalpha, -beta/delta, and -gamma) nuclear re …
Prostaglandins and the regulation of tumor growth.
Bishop-Bailey D, Calatayud S, Warner TD, Hla T, Mitchell JA. Bishop-Bailey D, et al. Among authors: warner td. J Environ Pathol Toxicol Oncol. 2002;21(2):93-101. J Environ Pathol Toxicol Oncol. 2002. PMID: 12086407 Review.
Recently, novel signaling pathways for PG derivatives have been discovered; in particular the PGD2 dehydration product 15-deoxy-delta(12,14)-(15d)-PGJ2 was identified as a ligand for the nuclear receptor/transcription factor, peroxisome proliferator-activated rec
Recently, novel signaling pathways for PG derivatives have been discovered; in particular the PGD2 dehydration product 15-deoxy-delta(12,14) …
Nongenomic signaling of the retinoid X receptor through binding and inhibiting Gq in human platelets.
Moraes LA, Swales KE, Wray JA, Damazo A, Gibbins JM, Warner TD, Bishop-Bailey D. Moraes LA, et al. Among authors: warner td. Blood. 2007 May 1;109(9):3741-4. doi: 10.1182/blood-2006-05-022566. Epub 2007 Jan 9. Blood. 2007. PMID: 17213293 Free PMC article.
Functional nongenomic effects of nuclear receptors are poorly understood; however, recently peroxisome proliferator-activated receptor (PPAR) gamma, PPARbeta, and the glucocorticoid receptor have all been found active in human platelets. ...Furthermore, our r …
Functional nongenomic effects of nuclear receptors are poorly understood; however, recently peroxisome proliferator-activated rece
Endogenous epoxygenases are modulators of monocyte/macrophage activity.
Bystrom J, Wray JA, Sugden MC, Holness MJ, Swales KE, Warner TD, Edin ML, Zeldin DC, Gilroy DW, Bishop-Bailey D. Bystrom J, et al. Among authors: warner td. PLoS One. 2011;6(10):e26591. doi: 10.1371/journal.pone.0026591. Epub 2011 Oct 19. PLoS One. 2011. PMID: 22028915 Free PMC article.
METHODOLOGY/PRINCIPAL FINDINGS: When transfected in vitro, CYP2J2 is an efficient activator of anti-inflammatory pathways through the nuclear receptor peroxisome proliferator-activated receptor (PPAR) alpha. ...
METHODOLOGY/PRINCIPAL FINDINGS: When transfected in vitro, CYP2J2 is an efficient activator of anti-inflammatory pathways through the nuc
Activation of PPARbeta/delta induces endothelial cell proliferation and angiogenesis.
Piqueras L, Reynolds AR, Hodivala-Dilke KM, Alfranca A, Redondo JM, Hatae T, Tanabe T, Warner TD, Bishop-Bailey D. Piqueras L, et al. Among authors: warner td. Arterioscler Thromb Vasc Biol. 2007 Jan;27(1):63-9. doi: 10.1161/01.ATV.0000250972.83623.61. Epub 2006 Oct 26. Arterioscler Thromb Vasc Biol. 2007. PMID: 17068288
OBJECTIVE: The role of the nuclear receptor peroxisome-proliferator activated receptor (PPAR)-beta/delta in endothelial cells remains unclear. ...
OBJECTIVE: The role of the nuclear receptor peroxisome-proliferator activated receptor (PPAR)-beta/delta in endothelial …
The farnesoid X receptor is expressed in breast cancer and regulates apoptosis and aromatase expression.
Swales KE, Korbonits M, Carpenter R, Walsh DT, Warner TD, Bishop-Bailey D. Swales KE, et al. Among authors: warner td. Cancer Res. 2006 Oct 15;66(20):10120-6. doi: 10.1158/0008-5472.CAN-06-2399. Cancer Res. 2006. PMID: 17047076 Free article.
Bile acids are present at high concentrations in breast cysts and in the plasma of postmenopausal women with breast cancer. The farnesoid X receptor (FXR) is a member of the nuclear receptor superfamily that regulates bile acid homeostasis. ...
Bile acids are present at high concentrations in breast cysts and in the plasma of postmenopausal women with breast cancer. The farnesoid X …
PPARbeta/delta agonists modulate platelet function via a mechanism involving PPAR receptors and specific association/repression of PKCalpha--brief report.
Ali FY, Hall MG, Desvergne B, Warner TD, Mitchell JA. Ali FY, et al. Among authors: warner td. Arterioscler Thromb Vasc Biol. 2009 Nov;29(11):1871-3. doi: 10.1161/ATVBAHA.109.193367. Epub 2009 Aug 20. Arterioscler Thromb Vasc Biol. 2009. PMID: 19696401
OBJECTIVE: Peroxisome proliferator-activated receptor beta/delta (PPARbeta/delta) is a nuclear receptor found in platelets. ...
OBJECTIVE: Peroxisome proliferator-activated receptor beta/delta (PPARbeta/delta) is a nuclear receptor found in platel …
Role of prostacyclin versus peroxisome proliferator-activated receptor beta receptors in prostacyclin sensing by lung fibroblasts.
Ali FY, Egan K, FitzGerald GA, Desvergne B, Wahli W, Bishop-Bailey D, Warner TD, Mitchell JA. Ali FY, et al. Among authors: warner td. Am J Respir Cell Mol Biol. 2006 Feb;34(2):242-6. doi: 10.1165/rcmb.2005-0289OC. Epub 2005 Oct 20. Am J Respir Cell Mol Biol. 2006. PMID: 16239641
These drugs act via cell surface prostacyclin receptors (IP receptors); however, some of them can also activate the nuclear receptor peroxisome proliferator-activated receptor beta (PPARbeta). ...The effects of treprostinil sodium on human lung cell prolifera …
These drugs act via cell surface prostacyclin receptors (IP receptors); however, some of them can also activate the nuclear recept
Intimal smooth muscle cells as a target for peroxisome proliferator-activated receptor-gamma ligand therapy.
Bishop-Bailey D, Hla T, Warner TD. Bishop-Bailey D, et al. Among authors: warner td. Circ Res. 2002 Aug 9;91(3):210-7. doi: 10.1161/01.res.0000029080.15742.85. Circ Res. 2002. PMID: 12169646
Activation of the nuclear receptor/transcription factor, peroxisome proliferator-activated receptor gamma (PPARgamma), is a newly defined target for limiting vascular pathologies. ...
Activation of the nuclear receptor/transcription factor, peroxisome proliferator-activated receptor gamma (PPARgamma), …