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Year Number of Results
2002 2
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2006 4
2007 3
2009 2
2011 1
2024 0

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Page 1
Role of nuclear receptor signaling in platelets: antithrombotic effects of PPARbeta.
Ali FY, Davidson SJ, Moraes LA, Traves SL, Paul-Clark M, Bishop-Bailey D, Warner TD, Mitchell JA. Ali FY, et al. Among authors: warner td. FASEB J. 2006 Feb;20(2):326-8. doi: 10.1096/fj.05-4395fje. Epub 2005 Dec 20. FASEB J. 2006. PMID: 16368717
These observations challenge our view of a nuclear receptor because PPARbeta is present and active in nonnucleated platelets. Furthermore, these data suggest that some of the antithrombotic actions of prostacyclin may be mediated via activation of PPARs. ...
These observations challenge our view of a nuclear receptor because PPARbeta is present and active in nonnucleated platelets. …
Endogenous epoxygenases are modulators of monocyte/macrophage activity.
Bystrom J, Wray JA, Sugden MC, Holness MJ, Swales KE, Warner TD, Edin ML, Zeldin DC, Gilroy DW, Bishop-Bailey D. Bystrom J, et al. Among authors: warner td. PLoS One. 2011;6(10):e26591. doi: 10.1371/journal.pone.0026591. Epub 2011 Oct 19. PLoS One. 2011. PMID: 22028915 Free PMC article.
METHODOLOGY/PRINCIPAL FINDINGS: When transfected in vitro, CYP2J2 is an efficient activator of anti-inflammatory pathways through the nuclear receptor peroxisome proliferator-activated receptor (PPAR) alpha. Human monocytes and macrophages contain PPARalpha and here …
METHODOLOGY/PRINCIPAL FINDINGS: When transfected in vitro, CYP2J2 is an efficient activator of anti-inflammatory pathways through the nuc …
Nongenomic signaling of the retinoid X receptor through binding and inhibiting Gq in human platelets.
Moraes LA, Swales KE, Wray JA, Damazo A, Gibbins JM, Warner TD, Bishop-Bailey D. Moraes LA, et al. Among authors: warner td. Blood. 2007 May 1;109(9):3741-4. doi: 10.1182/blood-2006-05-022566. Epub 2007 Jan 9. Blood. 2007. PMID: 17213293 Free PMC article.
Furthermore, our results demonstrate a novel nongenomic mode for nuclear receptor action and a functional cross-talk between G-protein and nuclear receptor signaling families....
Furthermore, our results demonstrate a novel nongenomic mode for nuclear receptor action and a functional cross-talk between G …
Prostaglandins and the regulation of tumor growth.
Bishop-Bailey D, Calatayud S, Warner TD, Hla T, Mitchell JA. Bishop-Bailey D, et al. Among authors: warner td. J Environ Pathol Toxicol Oncol. 2002;21(2):93-101. J Environ Pathol Toxicol Oncol. 2002. PMID: 12086407 Review.
Recently, novel signaling pathways for PG derivatives have been discovered; in particular the PGD2 dehydration product 15-deoxy-delta(12,14)-(15d)-PGJ2 was identified as a ligand for the nuclear receptor/transcription factor, peroxisome proliferator-activated recept …
Recently, novel signaling pathways for PG derivatives have been discovered; in particular the PGD2 dehydration product 15-deoxy-delta(12,14) …
Activation of PPARbeta/delta induces endothelial cell proliferation and angiogenesis.
Piqueras L, Reynolds AR, Hodivala-Dilke KM, Alfranca A, Redondo JM, Hatae T, Tanabe T, Warner TD, Bishop-Bailey D. Piqueras L, et al. Among authors: warner td. Arterioscler Thromb Vasc Biol. 2007 Jan;27(1):63-9. doi: 10.1161/01.ATV.0000250972.83623.61. Epub 2006 Oct 26. Arterioscler Thromb Vasc Biol. 2007. PMID: 17068288
OBJECTIVE: The role of the nuclear receptor peroxisome-proliferator activated receptor (PPAR)-beta/delta in endothelial cells remains unclear. ...
OBJECTIVE: The role of the nuclear receptor peroxisome-proliferator activated receptor (PPAR)-beta/delta in endothelial cells …
PPARbeta/delta agonists modulate platelet function via a mechanism involving PPAR receptors and specific association/repression of PKCalpha--brief report.
Ali FY, Hall MG, Desvergne B, Warner TD, Mitchell JA. Ali FY, et al. Among authors: warner td. Arterioscler Thromb Vasc Biol. 2009 Nov;29(11):1871-3. doi: 10.1161/ATVBAHA.109.193367. Epub 2009 Aug 20. Arterioscler Thromb Vasc Biol. 2009. PMID: 19696401
OBJECTIVE: Peroxisome proliferator-activated receptor beta/delta (PPARbeta/delta) is a nuclear receptor found in platelets. PPARbeta/delta agonists acutely inhibit platelet function within a few minutes of addition. ...
OBJECTIVE: Peroxisome proliferator-activated receptor beta/delta (PPARbeta/delta) is a nuclear receptor found in platelets. PP …
The farnesoid X receptor is expressed in breast cancer and regulates apoptosis and aromatase expression.
Swales KE, Korbonits M, Carpenter R, Walsh DT, Warner TD, Bishop-Bailey D. Swales KE, et al. Among authors: warner td. Cancer Res. 2006 Oct 15;66(20):10120-6. doi: 10.1158/0008-5472.CAN-06-2399. Cancer Res. 2006. PMID: 17047076 Free article.
The farnesoid X receptor (FXR) is a member of the nuclear receptor superfamily that regulates bile acid homeostasis. FXR was detected in normal and tumor breast tissue, with a high level of expression in ductal epithelial cells of normal breast and infiltrating duct …
The farnesoid X receptor (FXR) is a member of the nuclear receptor superfamily that regulates bile acid homeostasis. FXR was d …
Role of prostacyclin versus peroxisome proliferator-activated receptor beta receptors in prostacyclin sensing by lung fibroblasts.
Ali FY, Egan K, FitzGerald GA, Desvergne B, Wahli W, Bishop-Bailey D, Warner TD, Mitchell JA. Ali FY, et al. Among authors: warner td. Am J Respir Cell Mol Biol. 2006 Feb;34(2):242-6. doi: 10.1165/rcmb.2005-0289OC. Epub 2005 Oct 20. Am J Respir Cell Mol Biol. 2006. PMID: 16239641
These drugs act via cell surface prostacyclin receptors (IP receptors); however, some of them can also activate the nuclear receptor peroxisome proliferator-activated receptor beta (PPARbeta). We examined the possibility that PPARbeta is a therapeutic target for the …
These drugs act via cell surface prostacyclin receptors (IP receptors); however, some of them can also activate the nuclear recept …
11 results