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Wendan Decoction exerts therapeutic effects on insomnia by regulating gut microbiota and tryptophan metabolism.
Tian Y, Meng J, Zhang D, Zhai B, Cheng J, Zou J, Shi Y, Guo D. Tian Y, et al. Phytomedicine. 2025 Jun 29;145:157028. doi: 10.1016/j.phymed.2025.157028. Online ahead of print. Phytomedicine. 2025. PMID: 40618491
BACKGROUND: Insomnia has been a public problem threatening human health. Wendan Decoction (WDD) has good therapeutic effects on insomnia. However, its mechanism to improve sleep remains unclear. ...
BACKGROUND: Insomnia has been a public problem threatening human health. Wendan Decoction (WDD) has good therapeutic effects o …
[Wendan Decoction ameliorates metabolic phenotypes in rats with metabolic syndrome and phlegm syndrome by modulating the gut microbiota-bile acid axis].
Huang K, Qi J, Luo W, Lin Y, Chen M, Gan H. Huang K, et al. Nan Fang Yi Ke Da Xue Xue Bao. 2025 Jun 20;45(6):1174-1184. doi: 10.12122/j.issn.1673-4254.2025.06.07. Nan Fang Yi Ke Da Xue Xue Bao. 2025. PMID: 40579131 Free PMC article. Chinese.
OBJECTIVES: To investigate the therapeutic mechanism of Wendan Decoction for phlegm syndrome in rats with metabolic syndrome (MS). METHODS: Forty Wistar rats were randomly divided into normal control group (n=8) and 3 phlegm syndrome model groups (induced by high-fa …
OBJECTIVES: To investigate the therapeutic mechanism of Wendan Decoction for phlegm syndrome in rats with metabolic syndrome ( …
Xiong's Shiwei Wendan decoction attenuates plaque lesions and balances gut microbiota dysbiosis in ApoE-/- mice with high-fat diet.
Qian L, Liuchen X, Yue Y, Xiaopeng D, Jie W, Moye T, Yuxin L, Hongfeng GU, Xuejiao X. Qian L, et al. J Tradit Chin Med. 2025 Jun;45(3):508-517. doi: 10.19852/j.cnki.jtcm.2025.03.008. J Tradit Chin Med. 2025. PMID: 40524290 Free PMC article.
OBJECTIVE: To evaluate the anti-atherosclerotic potential and gut microbiota (GM) modulation effects of Xiong's Shiwei Wendan decoction (, XSWD). METHODS: For in vitro study, Tsuchiya human peripheral blood mononuclear cell-1 (THP-1) derived foam cells were used to …
OBJECTIVE: To evaluate the anti-atherosclerotic potential and gut microbiota (GM) modulation effects of Xiong's Shiwei Wendan deco …
Effects of modified Wendan Decoction combined with acupuncture on inflammatory factors and immune function in urticaria patients.
Tian Z, Dong J, Wang Y. Tian Z, et al. Arch Dermatol Res. 2025 Apr 11;317(1):696. doi: 10.1007/s00403-025-04210-1. Arch Dermatol Res. 2025. PMID: 40214812 Clinical Trial.
This study aimed to explore the effects of modified Wendan Decoction combined with acupuncture on serum inflammatory markers and immune function in patients suffering from urticaria. ...The recurrence rate was notably lower in the observation group compared to the c …
This study aimed to explore the effects of modified Wendan Decoction combined with acupuncture on serum inflammatory markers a …
A Comprehensive Quality Evaluation Strategy of Wendan Decoction Based on Qualitative, Fingerprint, and Quantitative Analyses.
Huang C, Chen S, Zhang Y, Xu Y, Zhao C, Zhao M. Huang C, et al. Phytochem Anal. 2025 Jul;36(5):1377-1395. doi: 10.1002/pca.3515. Epub 2025 Feb 17. Phytochem Anal. 2025. PMID: 39960036
INTRODUCTION: Wendan decoction (WDD), a classic Chinese medicine formula, has been used for the treatment of insomnia for hundreds of years. ...
INTRODUCTION: Wendan decoction (WDD), a classic Chinese medicine formula, has been used for the treatment of insomnia for hund …
Traditional Chinese medicine for premature ventricular contraction caused by obstructive sleep apnea: A case report and literature review.
Yue QQ, Hao YF, Li T, Miao HY, Chen BC, Li SY. Yue QQ, et al. Medicine (Baltimore). 2025 Jan 31;104(5):e41206. doi: 10.1097/MD.0000000000041206. Medicine (Baltimore). 2025. PMID: 39889189 Free PMC article. Review.
INTERVENTIONS: The patient visited Xiyuan Hospital on December 5, 2023, on the basis of existing Western medicine and TCM, using the modified Huanglian Wendan Decoction. OUTCOMES: After taking TCM for 21 days, the Holter tests were conducted again. ...
INTERVENTIONS: The patient visited Xiyuan Hospital on December 5, 2023, on the basis of existing Western medicine and TCM, using the modifie …
Integrated Network Pharmacology and Molecular Docking to Explore the Mechanisms of Ningshen Wendan Decoction in the Treatment of Schizophrenia.
Qi C, Yu Y, Lv H, Ju X, Ji X, Li P, He K. Qi C, et al. Alpha Psychiatry. 2024 Aug 1;25(4):456-464. doi: 10.5152/alphapsychiatry.2024.241560. eCollection 2024 Aug. Alpha Psychiatry. 2024. PMID: 39360308 Free PMC article.
Currently, no satisfactory pharmacological treatments have been identified. Although Ningshen Wendan decoction (NSWDD) has shown promising results in improving cognitive function in patients with schizophrenia, its underlying mechanism of action remains unclear. ...
Currently, no satisfactory pharmacological treatments have been identified. Although Ningshen Wendan decoction (NSWDD) has sho …
Systematic pharmacology and experimental validation to elucidate the inflammation-associated mechanism of Huanglian Wendan (HLWD) decoction in the treatment of MAFLD associated with atherosclerosis.
Liu ZC, Fu HJ, Li NC, Deng FJ, Gan YK, Ye YJ, Huang BH, Liu C, Chen JH, Li XF. Liu ZC, et al. J Ethnopharmacol. 2025 Jan 30;337(Pt 1):118841. doi: 10.1016/j.jep.2024.118841. Epub 2024 Sep 18. J Ethnopharmacol. 2025. PMID: 39299361
ETHNOPHARMACOLOGICAL RELEVANCE: Metabolic-associated fatty liver disease (MAFLD) and atherosclerosis are very common disorders that frequently coexist. The therapeutic efficacy of Huanglian Wendan (HLWD) decoction, a traditional Chinese medicine (TCM) prescription, …
ETHNOPHARMACOLOGICAL RELEVANCE: Metabolic-associated fatty liver disease (MAFLD) and atherosclerosis are very common disorders that frequent …
[Coronary heart disease: innovative understanding from traditional Chinese medicine and treatment by classic formulas].
Lan Y, Luo FK, Yu Y, Wang XY, Wang PQ, Xiong XJ. Lan Y, et al. Zhongguo Zhong Yao Za Zhi. 2024 Jul;49(13):3684-3692. doi: 10.19540/j.cnki.cjcmm.20240326.501. Zhongguo Zhong Yao Za Zhi. 2024. PMID: 39041141 Review. Chinese.
Accordingly, the patients with Qi depression should be treated with Chaihu Longgu Muli Decoction, and those with phlegm turbidity should be treated with Wendan Decoction and Gualou Xiebai Banxia Decoction. Xuefu Zhuyu Decoction and Guizhi Fuling …
Accordingly, the patients with Qi depression should be treated with Chaihu Longgu Muli Decoction, and those with phlegm turbidity sho …
70 results