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3,583 results

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Page 1
Werner syndrome: Clinical features, pathogenesis and potential therapeutic interventions.
Oshima J, Sidorova JM, Monnat RJ Jr. Oshima J, et al. Ageing Res Rev. 2017 Jan;33:105-114. doi: 10.1016/j.arr.2016.03.002. Epub 2016 Mar 15. Ageing Res Rev. 2017. PMID: 26993153 Free PMC article. Review.
Werner syndrome (WS) is a prototypical segmental progeroid syndrome characterized by multiple features consistent with accelerated aging. ...Recent discoveries of new progeroid loci found in atypical Werner cases continue to support the concept of geno
Werner syndrome (WS) is a prototypical segmental progeroid syndrome characterized by multiple features consistent with
Lessons for aging from Werner syndrome epigenetics.
Martin GM, Poot M, Haaf T. Martin GM, et al. Aging (Albany NY). 2020 Feb 5;12(3):2022-2023. doi: 10.18632/aging.102829. Epub 2020 Feb 5. Aging (Albany NY). 2020. PMID: 32023552 Free PMC article. No abstract available.
Werner syndrome associated with acroosteolysis.
Khalid T, Inam F, Iqbal MA. Khalid T, et al. Dermatol Online J. 2022 Aug 15;28(4). doi: 10.5070/D328458520. Dermatol Online J. 2022. PMID: 36259858
Werner syndrome (WS) is an autosomal recessive syndrome characterized by genomic instability that affects multiple body systems. ...Herein, we present a 28-year-old woman who presented with growth arrest, dyspigmentation, and acroosteolysis and was later diag
Werner syndrome (WS) is an autosomal recessive syndrome characterized by genomic instability that affects multiple body
Studying Werner syndrome to elucidate mechanisms and therapeutics of human aging and age-related diseases.
Lautrup S, Caponio D, Cheung HH, Piccoli C, Stevnsner T, Chan WY, Fang EF. Lautrup S, et al. Biogerontology. 2019 Jun;20(3):255-269. doi: 10.1007/s10522-019-09798-2. Epub 2019 Jan 21. Biogerontology. 2019. PMID: 30666569 Review.
Unraveling the sophisticated molecular mechanisms of the human aging process may provide novel strategies to extend 'healthy aging' and the cure of human aging-related diseases. Werner syndrome (WS), is a heritable human premature aging disease caused by mutations i …
Unraveling the sophisticated molecular mechanisms of the human aging process may provide novel strategies to extend 'healthy aging' and the …
Werner syndrome in a Lebanese family.
Jaafar B, Nasrallah M, Sievers B, Oshima J, Lessel D. Jaafar B, et al. Am J Med Genet A. 2022 May;188(5):1630-1634. doi: 10.1002/ajmg.a.62654. Epub 2022 Jan 17. Am J Med Genet A. 2022. PMID: 35037378 Free PMC article.
Werner syndrome (WS) is an extremely rare, autosomal recessive segmental progeroid disorder caused by biallelic pathogenic variants in the WRN, which encodes a multifunctional nuclear protein that belongs to the RecQ family of DNA helicases. ...
Werner syndrome (WS) is an extremely rare, autosomal recessive segmental progeroid disorder caused by biallelic pathogenic var
Werner's syndrome.
Duvic M, Lemak NA. Duvic M, et al. Dermatol Clin. 1995 Jan;13(1):163-8. Dermatol Clin. 1995. PMID: 7712642 Review.
Werner's syndrome is a rare autosomal recessive disorder that affects connective tissue throughout the body. ...
Werner's syndrome is a rare autosomal recessive disorder that affects connective tissue throughout the body. ...
Werner's syndrome.
Keen A, Hassan I. Keen A, et al. Indian J Dermatol Venereol Leprol. 2012 May-Jun;78(3):380-1. doi: 10.4103/0378-6323.95469. Indian J Dermatol Venereol Leprol. 2012. PMID: 22565447 Free article. No abstract available.
[Werner's syndrome].
Piussan C. Piussan C. Arch Fr Pediatr. 1992 Aug-Sep;49(7):647-55. Arch Fr Pediatr. 1992. PMID: 1476485 Review. French. No abstract available.
Werner Syndrome Protein Expression in Breast Cancer.
Savva C, Sadiq M, Sheikh O, Karim S, Trivedi S, Green AR, Rakha EA, Madhusudan S, Arora A. Savva C, et al. Clin Breast Cancer. 2021 Feb;21(1):57-73.e7. doi: 10.1016/j.clbc.2020.07.013. Epub 2020 Jul 25. Clin Breast Cancer. 2021. PMID: 32919863
INTRODUCTION: Werner protein (WRN) plays an important role in DNA repair, replication, transcription, and consequently genomic stability via its DNA-helicase and exonuclease activity. Loss of function of WRN is associated with Werner syndrome (WS), which is c …
INTRODUCTION: Werner protein (WRN) plays an important role in DNA repair, replication, transcription, and consequently genomic stabil …
3,583 results