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128 results

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Page 1
Apolipoprotein E aggregation in microglia initiates Alzheimer's disease pathology by seeding β-amyloidosis.
Kaji S, Berghoff SA, Spieth L, Schlaphoff L, Sasmita AO, Vitale S, Büschgens L, Kedia S, Zirngibl M, Nazarenko T, Damkou A, Hosang L, Depp C, Kamp F, Scholz P, Ewers D, Giera M, Ischebeck T, Wurst W, Wefers B, Schifferer M, Willem M, Nave KA, Haass C, Arzberger T, Jäkel S, Wirths O, Saher G, Simons M. Kaji S, et al. Immunity. 2024 Nov 12;57(11):2651-2668.e12. doi: 10.1016/j.immuni.2024.09.014. Epub 2024 Oct 16. Immunity. 2024. PMID: 39419029 Free article.
Myelin dysfunction drives amyloid-β deposition in models of Alzheimer's disease.
Depp C, Sun T, Sasmita AO, Spieth L, Berghoff SA, Nazarenko T, Overhoff K, Steixner-Kumar AA, Subramanian S, Arinrad S, Ruhwedel T, Möbius W, Göbbels S, Saher G, Werner HB, Damkou A, Zampar S, Wirths O, Thalmann M, Simons M, Saito T, Saido T, Krueger-Burg D, Kawaguchi R, Willem M, Haass C, Geschwind D, Ehrenreich H, Stassart R, Nave KA. Depp C, et al. Nature. 2023 Jun;618(7964):349-357. doi: 10.1038/s41586-023-06120-6. Epub 2023 May 31. Nature. 2023. PMID: 37258678 Free PMC article.
Oligodendrocytes produce amyloid-β and contribute to plaque formation alongside neurons in Alzheimer's disease model mice.
Sasmita AO, Depp C, Nazarenko T, Sun T, Siems SB, Ong EC, Nkeh YB, Böhler C, Yu X, Bues B, Evangelista L, Mao S, Morgado B, Wu Z, Ruhwedel T, Subramanian S, Börensen F, Overhoff K, Spieth L, Berghoff SA, Sadleir KR, Vassar R, Eggert S, Goebbels S, Saito T, Saido T, Saher G, Möbius W, Castelo-Branco G, Klafki HW, Wirths O, Wiltfang J, Jäkel S, Yan R, Nave KA. Sasmita AO, et al. Nat Neurosci. 2024 Sep;27(9):1668-1674. doi: 10.1038/s41593-024-01730-3. Epub 2024 Aug 5. Nat Neurosci. 2024. PMID: 39103558 Free PMC article.
Apolipoprotein E aggregation in microglia initiates Alzheimer's disease pathology by seeding β-amyloidosis.
Kaji S, Berghoff SA, Spieth L, Schlaphoff L, Sasmita AO, Vitale S, Büschgens L, Kedia S, Zirngibl M, Nazarenko T, Damkou A, Hosang L, Depp C, Kamp F, Scholz P, Ewers D, Giera M, Ischebeck T, Wurst W, Wefers B, Schifferer M, Willem M, Nave KA, Haass C, Arzberger T, Jäkel S, Wirths O, Saher G, Simons M. Kaji S, et al. Immunity. 2025 Jan 14;58(1):263. doi: 10.1016/j.immuni.2024.11.024. Epub 2024 Dec 4. Immunity. 2025. PMID: 39637851 No abstract available.
Immunotherapy Targeting Amyloid-β Peptides in Alzheimer’s Disease.
Zampar S, Wirths O. Zampar S, et al. In: Huang X, editor. Alzheimer’s Disease: Drug Discovery [Internet]. Brisbane (AU): Exon Publications; 2020 Dec 18. Chapter 2. In: Huang X, editor. Alzheimer’s Disease: Drug Discovery [Internet]. Brisbane (AU): Exon Publications; 2020 Dec 18. Chapter 2. PMID: 33400461 Free Books & Documents. Review.
N-Terminally Truncated Aβ Peptide Variants in Alzheimer’s Disease.
Wirths O, Zampar S, Weggen S. Wirths O, et al. In: Wisniewski T, editor. Alzheimer’s Disease [Internet]. Brisbane (AU): Codon Publications; 2019 Dec 20. Chapter 7. In: Wisniewski T, editor. Alzheimer’s Disease [Internet]. Brisbane (AU): Codon Publications; 2019 Dec 20. Chapter 7. PMID: 31895514 Free Books & Documents. Review.
128 results