Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My Custom Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2000 2
2007 1
2008 1
2010 2
2011 3
2012 1
2013 1
2015 1
2016 4
2017 3
2018 2
2019 2
2020 3
2021 4
2022 2
2023 3
2024 2
2025 0

Publication date

Text availability

Article attribute

Article type

Additional filters

Article Language

Species

Sex

Age

Other

Search Results

33 results

Results by year

Filters applied: . Clear all
Page 1
An investigation into the stress-relieving and pharmacological actions of an ashwagandha (Withania somnifera) extract: A randomized, double-blind, placebo-controlled study.
Lopresti AL, Smith SJ, Malvi H, Kodgule R. Lopresti AL, et al. Medicine (Baltimore). 2019 Sep;98(37):e17186. doi: 10.1097/MD.0000000000017186. Medicine (Baltimore). 2019. PMID: 31517876 Free PMC article. Clinical Trial.
BACKGROUND: Ashwagandha (Withania somnifera (L.) Dunal) is a herb traditionally used to reduce stress and enhance wellbeing. The aim of this study was to investigate its anxiolytic effects on adults with self-reported high stress and to examine potential mech …
BACKGROUND: Ashwagandha (Withania somnifera (L.) Dunal) is a herb traditionally used to reduce stress and enhance wellbeing. T …
Medicinal herbs for the treatment of anxiety: A systematic review and network meta-analysis.
Zhang W, Yan Y, Wu Y, Yang H, Zhu P, Yan F, Zhao R, Tian P, Wang T, Fan Q, Su Z. Zhang W, et al. Pharmacol Res. 2022 May;179:106204. doi: 10.1016/j.phrs.2022.106204. Epub 2022 Apr 1. Pharmacol Res. 2022. PMID: 35378276 Review.
Ginkgo biloba (MD: -4.63, 95% CrI: -9.01 to -0.23) and Withania somnifera (MD: -4.90, 95% CrI: -9.70 to -0.17) were efficacious, as measured by HAMA scores but the trials were limited by their small sample sizes. Galphimia glauca (MD: -1.23, 95% CrI: -4.68 to 2.23) …
Ginkgo biloba (MD: -4.63, 95% CrI: -9.01 to -0.23) and Withania somnifera (MD: -4.90, 95% CrI: -9.70 to -0.17) were efficaciou …
An overview on ashwagandha: a Rasayana (rejuvenator) of Ayurveda.
Singh N, Bhalla M, de Jager P, Gilca M. Singh N, et al. Afr J Tradit Complement Altern Med. 2011;8(5 Suppl):208-13. doi: 10.4314/ajtcam.v8i5S.9. Epub 2011 Jul 3. Afr J Tradit Complement Altern Med. 2011. PMID: 22754076 Free PMC article. Review.
Withania somnifera (Ashawagandha) is very revered herb of the Indian Ayurvedic system of medicine as a Rasayana (tonic). ...In experimental models it increases the stamina of rats during swimming endurance test and prevented adrenal gland changes of ascorbic acid an …
Withania somnifera (Ashawagandha) is very revered herb of the Indian Ayurvedic system of medicine as a Rasayana (tonic). ...In …
Withania somnifera as a Potential Anxiolytic and Anti-inflammatory Candidate Against Systemic Lipopolysaccharide-Induced Neuroinflammation.
Gupta M, Kaur G. Gupta M, et al. Neuromolecular Med. 2018 Sep;20(3):343-362. doi: 10.1007/s12017-018-8497-7. Epub 2018 May 30. Neuromolecular Med. 2018. PMID: 29846872
Natural products are emerging better therapeutic agents due to their affordability and inherent pleiotropic biological activities. In Ayurveda, Ashwagandha (Withania somnifera) is well known for its immunomodulatory properties. ...
Natural products are emerging better therapeutic agents due to their affordability and inherent pleiotropic biological activities. In …
Withania somnifera as a potential anxiolytic and immunomodulatory agent in acute sleep deprived female Wistar rats.
Kaur T, Singh H, Mishra R, Manchanda S, Gupta M, Saini V, Sharma A, Kaur G. Kaur T, et al. Mol Cell Biochem. 2017 Mar;427(1-2):91-101. doi: 10.1007/s11010-016-2900-1. Epub 2016 Dec 21. Mol Cell Biochem. 2017. PMID: 28004351
The current study was aimed to elucidate the effects of acute SD on immune function and its modulation by water extract from leaves of Withania somnifera (ASH-WEX). Three groups of animals, i.e. Vehicle-Undisturbed sleep (VUD), Vehicle-Sleep deprived (VSD) and ASH-W …
The current study was aimed to elucidate the effects of acute SD on immune function and its modulation by water extract from leaves of Wi …
The biologically active compound of Withania somnifera (L.) Dunal, docosanyl ferulate, is endowed with potent anxiolytic properties but devoid of typical benzodiazepine-like side effects.
Maccioni R, Cottiglia F, Maccioni E, Talani G, Sanna E, Bassareo V, Kasture SB, Acquas E. Maccioni R, et al. J Psychopharmacol. 2021 Oct;35(10):1277-1284. doi: 10.1177/02698811211008588. Epub 2021 May 3. J Psychopharmacol. 2021. PMID: 33934670
BACKGROUND: Clinical and experimental studies support the therapeutic potential of Withania somnifera (WS) (L.) Dunal on anxiety disorders. This potential is attributable to components present in different plant extracts; however, the individual compound(s) endowed …
BACKGROUND: Clinical and experimental studies support the therapeutic potential of Withania somnifera (WS) (L.) Dunal on anxie …
Anxiolytic-antidepressant activity of Withania somnifera glycowithanolides: an experimental study.
Bhattacharya SK, Bhattacharya A, Sairam K, Ghosal S. Bhattacharya SK, et al. Phytomedicine. 2000 Dec;7(6):463-9. doi: 10.1016/S0944-7113(00)80030-6. Phytomedicine. 2000. PMID: 11194174
The roots of Withania somnifera (WS) are used extensively in Ayurveda, the classical Indian system of medicine, and WS is categorized as a rasayana, which are used to promote physical and mental health, to provide defence against disease and adverse environmental fa …
The roots of Withania somnifera (WS) are used extensively in Ayurveda, the classical Indian system of medicine, and WS is cate …
Assessment of the Efficacy of Withania somnifera Root Extract in Patients with Generalized Anxiety Disorder: A Randomized Double-blind Placebo- Controlled Trial.
Fuladi S, Emami SA, Mohammadpour AH, Karimani A, Manteghi AA, Sahebkar A. Fuladi S, et al. Curr Rev Clin Exp Pharmacol. 2021;16(2):191-196. doi: 10.2174/1574884715666200413120413. Curr Rev Clin Exp Pharmacol. 2021. PMID: 32282308 Clinical Trial.
Therefore, it is necessary to find some new therapeutic approaches with fewer side effects. Withania somnifera is a plant with GABAergic property responsible for its anxiolytic effect. The aim of this study was to investigate the effect of W. somnifera …
Therefore, it is necessary to find some new therapeutic approaches with fewer side effects. Withania somnifera is a plant with …
A double-blind, placebo-controlled evaluation of the anxiolytic efficacy ff an ethanolic extract of withania somnifera.
Andrade C, Aswath A, Chaturvedi SK, Srinivasa M, Raguram R. Andrade C, et al. Indian J Psychiatry. 2000 Jul;42(3):295-301. Indian J Psychiatry. 2000. PMID: 21407960 Free PMC article.
A double-blind, placebo-controlled study was conducted to evaluate the efficacy an ethanolic extract of Aswagandha (Withania somnifera), in patients with ICD-10 anxiety disorders. The sample comprised 39 subjects, of whom 20 received the drug and 19 received placebo …
A double-blind, placebo-controlled study was conducted to evaluate the efficacy an ethanolic extract of Aswagandha (Withania somni …
33 results