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An investigation into the stress-relieving and pharmacological actions of an ashwagandha (Withania somnifera) extract: A randomized, double-blind, placebo-controlled study.
Lopresti AL, Smith SJ, Malvi H, Kodgule R. Lopresti AL, et al. Medicine (Baltimore). 2019 Sep;98(37):e17186. doi: 10.1097/MD.0000000000017186. Medicine (Baltimore). 2019. PMID: 31517876 Free PMC article. Clinical Trial.
BACKGROUND: Ashwagandha (Withania somnifera (L.) Dunal) is a herb traditionally used to reduce stress and enhance wellbeing. ...Sixty adults were randomly allocated to take either a placebo or 240 mg of a standardized ashwagandha extract (Shoden) once daily. Outcome …
BACKGROUND: Ashwagandha (Withania somnifera (L.) Dunal) is a herb traditionally used to reduce stress and enhance wellbeing. . …
An overview on ashwagandha: a Rasayana (rejuvenator) of Ayurveda.
Singh N, Bhalla M, de Jager P, Gilca M. Singh N, et al. Afr J Tradit Complement Altern Med. 2011;8(5 Suppl):208-13. doi: 10.4314/ajtcam.v8i5S.9. Epub 2011 Jul 3. Afr J Tradit Complement Altern Med. 2011. PMID: 22754076 Free PMC article. Review.
Withania somnifera (Ashawagandha) is very revered herb of the Indian Ayurvedic system of medicine as a Rasayana (tonic). ...Pretreatment with Withania somnifera (WS) showed significance protection against stress induced gastric ulcers. ...
Withania somnifera (Ashawagandha) is very revered herb of the Indian Ayurvedic system of medicine as a Rasayana (tonic). ...Pr …
Medicinal herbs for the treatment of anxiety: A systematic review and network meta-analysis.
Zhang W, Yan Y, Wu Y, Yang H, Zhu P, Yan F, Zhao R, Tian P, Wang T, Fan Q, Su Z. Zhang W, et al. Pharmacol Res. 2022 May;179:106204. doi: 10.1016/j.phrs.2022.106204. Epub 2022 Apr 1. Pharmacol Res. 2022. PMID: 35378276 Review.
BACKGROUND: Anxiety disorder is a common psychiatric illness. Medicinal herbs have become a field of interest in the treatment of anxiety. ...Kava was found to be an effective anxiolytic (MD: -2.46, 95% CrI: -4.47 to -0.32) but possibly ineffective in patient …
BACKGROUND: Anxiety disorder is a common psychiatric illness. Medicinal herbs have become a field of interest in the treatment of …
Adaptogenic and Anxiolytic Effects of Ashwagandha Root Extract in Healthy Adults: A Double-blind, Randomized, Placebo-controlled Clinical Study.
Salve J, Pate S, Debnath K, Langade D. Salve J, et al. Cureus. 2019 Dec 25;11(12):e6466. doi: 10.7759/cureus.6466. Cureus. 2019. PMID: 32021735 Free PMC article.
Background Stress, anxiety and impeded sleep are a frequent feature of life in modern societies. ...Stress was assessed using PSS at baseline, four weeks and eight weeks. Anxiety was assessed using the Hamilton-Anxiety (HAM-A) scale and serum cortisol was mea …
Background Stress, anxiety and impeded sleep are a frequent feature of life in modern societies. ...Stress was assessed using PSS at …
Assessment of the Efficacy of Withania somnifera Root Extract in Patients with Generalized Anxiety Disorder: A Randomized Double-blind Placebo- Controlled Trial.
Fuladi S, Emami SA, Mohammadpour AH, Karimani A, Manteghi AA, Sahebkar A. Fuladi S, et al. Curr Rev Clin Exp Pharmacol. 2021;16(2):191-196. doi: 10.2174/1574884715666200413120413. Curr Rev Clin Exp Pharmacol. 2021. PMID: 32282308 Clinical Trial.
Therefore, it is necessary to find some new therapeutic approaches with fewer side effects. Withania somnifera is a plant with GABAergic property responsible for its anxiolytic effect. The aim of this study was to investigate the effect of W. somnifera …
Therefore, it is necessary to find some new therapeutic approaches with fewer side effects. Withania somnifera is a plant with …
Withania somnifera as a Potential Anxiolytic and Anti-inflammatory Candidate Against Systemic Lipopolysaccharide-Induced Neuroinflammation.
Gupta M, Kaur G. Gupta M, et al. Neuromolecular Med. 2018 Sep;20(3):343-362. doi: 10.1007/s12017-018-8497-7. Epub 2018 May 30. Neuromolecular Med. 2018. PMID: 29846872
Natural products are emerging better therapeutic agents due to their affordability and inherent pleiotropic biological activities. In Ayurveda, Ashwagandha (Withania somnifera) is well known for its immunomodulatory properties. ...
Natural products are emerging better therapeutic agents due to their affordability and inherent pleiotropic biological activities. In …
Withania somnifera as a potential anxiolytic and immunomodulatory agent in acute sleep deprived female Wistar rats.
Kaur T, Singh H, Mishra R, Manchanda S, Gupta M, Saini V, Sharma A, Kaur G. Kaur T, et al. Mol Cell Biochem. 2017 Mar;427(1-2):91-101. doi: 10.1007/s11010-016-2900-1. Epub 2016 Dec 21. Mol Cell Biochem. 2017. PMID: 28004351
The current study was aimed to elucidate the effects of acute SD on immune function and its modulation by water extract from leaves of Withania somnifera (ASH-WEX). Three groups of animals, i.e. Vehicle-Undisturbed sleep (VUD), Vehicle-Sleep deprived (VSD) and ASH-W …
The current study was aimed to elucidate the effects of acute SD on immune function and its modulation by water extract from leaves of Wi …
The biologically active compound of Withania somnifera (L.) Dunal, docosanyl ferulate, is endowed with potent anxiolytic properties but devoid of typical benzodiazepine-like side effects.
Maccioni R, Cottiglia F, Maccioni E, Talani G, Sanna E, Bassareo V, Kasture SB, Acquas E. Maccioni R, et al. J Psychopharmacol. 2021 Oct;35(10):1277-1284. doi: 10.1177/02698811211008588. Epub 2021 May 3. J Psychopharmacol. 2021. PMID: 33934670
BACKGROUND: Clinical and experimental studies support the therapeutic potential of Withania somnifera (WS) (L.) Dunal on anxiety disorders. This potential is attributable to components present in different plant extracts; however, the individual compound(s) e …
BACKGROUND: Clinical and experimental studies support the therapeutic potential of Withania somnifera (WS) (L.) Dunal on an …
Plant-based medicines for anxiety disorders, part 2: a review of clinical studies with supporting preclinical evidence.
Sarris J, McIntyre E, Camfield DA. Sarris J, et al. CNS Drugs. 2013 Apr;27(4):301-19. doi: 10.1007/s40263-013-0059-9. CNS Drugs. 2013. PMID: 23653088 Review.
Research in the area of herbal psychopharmacology has revealed a variety of promising medicines that may provide benefit in the treatment of general anxiety and specific anxiety disorders. However, a comprehensive review of plant-based anxiolytics has been ab …
Research in the area of herbal psychopharmacology has revealed a variety of promising medicines that may provide benefit in the treatment of …
Anxiolytic-antidepressant activity of Withania somnifera glycowithanolides: an experimental study.
Bhattacharya SK, Bhattacharya A, Sairam K, Ghosal S. Bhattacharya SK, et al. Phytomedicine. 2000 Dec;7(6):463-9. doi: 10.1016/S0944-7113(00)80030-6. Phytomedicine. 2000. PMID: 11194174
The roots of Withania somnifera (WS) are used extensively in Ayurveda, the classical Indian system of medicine, and WS is categorized as a rasayana, which are used to promote physical and mental health, to provide defence against disease and adverse environmental fa …
The roots of Withania somnifera (WS) are used extensively in Ayurveda, the classical Indian system of medicine, and WS is cate …
31 results