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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1947 1
1948 1
1953 1
1954 1
1957 2
1958 2
1959 3
1962 2
1963 4
1964 7
1965 5
1966 5
1967 4
1968 7
1969 8
1970 5
1971 7
1972 8
1973 20
1974 30
1975 29
1976 31
1977 35
1978 35
1979 30
1980 33
1981 33
1982 39
1983 64
1984 50
1985 51
1986 46
1987 57
1988 59
1989 59
1990 71
1991 63
1992 81
1993 88
1994 94
1995 73
1996 73
1997 76
1998 87
1999 94
2000 115
2001 96
2002 85
2003 97
2004 100
2005 100
2006 108
2007 96
2008 132
2009 91
2010 105
2011 132
2012 129
2013 117
2014 141
2015 122
2016 139
2017 128
2018 130
2019 148
2020 135
2021 177
2022 164
2023 156
2024 137
2025 155
2026 103

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4,564 results

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Page 1
Antiseizure Medication Withdrawal in Seizure-Free Patients: Practice Advisory Update Summary: Report of the AAN Guideline Subcommittee.
Gloss D, Pargeon K, Pack A, Varma J, French JA, Tolchin B, Dlugos DJ, Mikati MA, Harden C; AAN Guideline Subcommittee. Gloss D, et al. Neurology. 2021 Dec 7;97(23):1072-1081. doi: 10.1212/WNL.0000000000012944. Neurology. 2021. PMID: 34873018
There is insufficient evidence that the rate of seizure recurrence with ASM withdrawal following epilepsy surgery after 1 year of seizure freedom vs after 4 years is not significantly different than maintaining patients on ASMs. ...In seizure-free adul …
There is insufficient evidence that the rate of seizure recurrence with ASM withdrawal following epilepsy surgery after 1 year …
Individualised prediction model of seizure recurrence and long-term outcomes after withdrawal of antiepileptic drugs in seizure-free patients: a systematic review and individual participant data meta-analysis.
Lamberink HJ, Otte WM, Geerts AT, Pavlovic M, Ramos-Lizana J, Marson AG, Overweg J, Sauma L, Specchio LM, Tennison M, Cardoso TMO, Shinnar S, Schmidt D, Geleijns K, Braun KPJ. Lamberink HJ, et al. Lancet Neurol. 2017 Jul;16(7):523-531. doi: 10.1016/S1474-4422(17)30114-X. Epub 2017 May 5. Lancet Neurol. 2017. PMID: 28483337 Free article.
Independent predictors of seizure recurrence were epilepsy duration before remission, seizure-free interval before antiepileptic drug withdrawal, age at onset of epilepsy, history of febrile seizures, number of seizures before remission, absence …
Independent predictors of seizure recurrence were epilepsy duration before remission, seizure-free interval before antiepilept …
Recommendation for a definition of acute symptomatic seizure.
Beghi E, Carpio A, Forsgren L, Hesdorffer DC, Malmgren K, Sander JW, Tomson T, Hauser WA. Beghi E, et al. Epilepsia. 2010 Apr;51(4):671-5. doi: 10.1111/j.1528-1167.2009.02285.x. Epub 2009 Sep 3. Epilepsia. 2010. PMID: 19732133
PURPOSE: To consider the definition of acute symptomatic seizures for epidemiological studies, and to refine the criteria used to distinguish these seizures from unprovoked seizures for specific etiologies. ...DISCUSSION: Acute symptomatic seizures mus …
PURPOSE: To consider the definition of acute symptomatic seizures for epidemiological studies, and to refine the criteria used to dis …
[Withdrawal seizure].
Yoshimoto H. Yoshimoto H. Ryoikibetsu Shokogun Shirizu. 2003;(40):437-40. Ryoikibetsu Shokogun Shirizu. 2003. PMID: 14626155 Review. Japanese. No abstract available.
Seizure Occurring During Baclofen Monotherapy for Phenibut Withdrawal.
Patt A, Fox H, Wells L, Theobald J, Feldman R. Patt A, et al. Clin Neuropharmacol. 2023 Mar-Apr 01;46(2):79-81. doi: 10.1097/WNF.0000000000000542. Epub 2023 Feb 4. Clin Neuropharmacol. 2023. PMID: 36735548
Potential risks of underdosing baclofen if used as monotherapy in PW may include seizures as withdrawal progresses. Baclofen's role in therapy may be more appropriate as an adjunct than a cornerstone of therapy. Treatment done in consultation with providers experien …
Potential risks of underdosing baclofen if used as monotherapy in PW may include seizures as withdrawal progresses. Baclofen's …
Antiseizure Medication Withdrawal in Seizure-Free Patients: What is New for the Pediatrician?
Gupta A, Kumar K. Gupta A, et al. Indian Pediatr. 2022 Aug 15;59(8):648-651. Indian Pediatr. 2022. PMID: 35962660 Free article.
The American Academy of Neurology (AAN) has recently updated its practise advisory on antiseizure medication withdrawal. The recommendations have been formulated for pediatric as well as adult epilepsy, with emphasis on the risk factors for seizure relapse, occurren …
The American Academy of Neurology (AAN) has recently updated its practise advisory on antiseizure medication withdrawal. The recommen …
Antiepileptic drug withdrawal and seizure severity in the epilepsy monitoring unit.
Duy PQ, Krauss GL, Crone NE, Ma M, Johnson EL. Duy PQ, et al. Epilepsy Behav. 2020 Aug;109:107128. doi: 10.1016/j.yebeh.2020.107128. Epub 2020 May 14. Epilepsy Behav. 2020. PMID: 32417383
We included 114 presurgical patients who had AEDs reduced and at least one seizure during the admission. We compared AED dosages at which FS versus focal to bilateral tonic-clonic seizures (f-BTCS), seizure clusters, and lorazepam administration occurred. ... …
We included 114 presurgical patients who had AEDs reduced and at least one seizure during the admission. We compared AED dosages at w …
Alcohol withdrawal produces changes in excitability, population discharge probability, and seizure threshold.
Alberto GE, Klorig DC, Goldstein AT, Godwin DW. Alberto GE, et al. Alcohol Clin Exp Res (Hoboken). 2023 Feb;47(2):211-218. doi: 10.1111/acer.15004. Epub 2023 Jan 4. Alcohol Clin Exp Res (Hoboken). 2023. PMID: 36543333 Free PMC article.
This shift in excitability mirrored an increase in the number of spontaneous interictal spikes during withdrawal. In addition, Withdrawal lowered seizure thresholds and increased seizure severity in optogenetically kindled mice. CONCLUSION: We demonstr …
This shift in excitability mirrored an increase in the number of spontaneous interictal spikes during withdrawal. In addition, Wit …
Trial of Cannabidiol for Drug-Resistant Seizures in the Dravet Syndrome.
Devinsky O, Cross JH, Laux L, Marsh E, Miller I, Nabbout R, Scheffer IE, Thiele EA, Wright S; Cannabidiol in Dravet Syndrome Study Group. Devinsky O, et al. N Engl J Med. 2017 May 25;376(21):2011-2020. doi: 10.1056/NEJMoa1611618. N Engl J Med. 2017. PMID: 28538134 Free article. Clinical Trial.
BACKGROUND: The Dravet syndrome is a complex childhood epilepsy disorder that is associated with drug-resistant seizures and a high mortality rate. We studied cannabidiol for the treatment of drug-resistant seizures in the Dravet syndrome. ...There were more with …
BACKGROUND: The Dravet syndrome is a complex childhood epilepsy disorder that is associated with drug-resistant seizures and a high m …
Seizure-relapse risk following antiseizure medication withdrawal in children with non-lesional focal epilepsy.
Kanemura H, Miyasato Y, Tomi Y, Sano F. Kanemura H, et al. Epilepsy Behav. 2025 Aug;169:110439. doi: 10.1016/j.yebeh.2025.110439. Epub 2025 Apr 26. Epilepsy Behav. 2025. PMID: 40288066
AIMS: We investigated seizure-relapse risk following antiseizure medication (ASM) withdrawal in children with focal epilepsy (FE) who were leading to seizure remission by ASM monotherapy without drug replacement. ...All children discontinued ASMs after more t …
AIMS: We investigated seizure-relapse risk following antiseizure medication (ASM) withdrawal in children with focal epilepsy ( …
4,564 results