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Table representation of search results timeline featuring number of search results per year.

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1966 2
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127 results

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Page 1
Ensemble Allosteric Model for the Modified Wobble Hypothesis.
Sarkar AK, Sarzynska J, Lahiri A. Sarkar AK, et al. J Phys Chem Lett. 2020 Aug 6;11(15):6337-6343. doi: 10.1021/acs.jpclett.0c00854. Epub 2020 Jul 23. J Phys Chem Lett. 2020. PMID: 32701298
The residue 2-thiouridine (s(2)U) provides a remarkable example for the "modified wobble" hypothesis, which postulates that some post-transcriptional modifications at the wobble position of tRNAs restrict recognition of degenerate codons. ...The conformationa …
The residue 2-thiouridine (s(2)U) provides a remarkable example for the "modified wobble" hypothesis, which postulates that so …
Celebrating wobble decoding: Half a century and still much is new.
Agris PF, Eruysal ER, Narendran A, Väre VYP, Vangaveti S, Ranganathan SV. Agris PF, et al. RNA Biol. 2018;15(4-5):537-553. doi: 10.1080/15476286.2017.1356562. Epub 2017 Sep 21. RNA Biol. 2018. PMID: 28812932 Free PMC article. Review.
A simple post-transcriptional modification of tRNA, deamination of adenosine to inosine at the first, or wobble, position of the anticodon, inspired Francis Crick's Wobble Hypothesis 50 years ago. ...Their contribution with regards to chemistry, structure and …
A simple post-transcriptional modification of tRNA, deamination of adenosine to inosine at the first, or wobble, position of the anti …
Bacterial tRNA landscape revisited.
Pust MM, Timmis KN, Tümmler B. Pust MM, et al. Environ Microbiol. 2022 Jul;24(7):2890-2894. doi: 10.1111/1462-2920.16033. Epub 2022 May 16. Environ Microbiol. 2022. PMID: 35570829
The updated Wobble Hypothesis reasonably explains why some 40 tRNA species are sufficient to decode the 61 amino acid codons of the Universal Genetic Code. ...
The updated Wobble Hypothesis reasonably explains why some 40 tRNA species are sufficient to decode the 61 amino acid codons o …
tRNA's wobble decoding of the genome: 40 years of modification.
Agris PF, Vendeix FA, Graham WD. Agris PF, et al. J Mol Biol. 2007 Feb 9;366(1):1-13. doi: 10.1016/j.jmb.2006.11.046. Epub 2006 Nov 15. J Mol Biol. 2007. PMID: 17187822 Review.
The ambiguity of that recognition resided in the third base-pair, giving rise to the Wobble Hypothesis. Post-transcriptional modifications at tRNA's wobble position 34, especially modifications of uridine 34, enable wobble to occur. The Modified Wob …
The ambiguity of that recognition resided in the third base-pair, giving rise to the Wobble Hypothesis. Post-transcriptional m …
The bacterial tRNA-modifying enzyme tRNAIle lysidine synthetase is genetically conserved but catalytically variable.
Muraski MJ, Guinto FC Jr, Nilsson EM, Dabdoub JB, Robinson SC, Jiang Y, Shen Z, Alexander RW. Muraski MJ, et al. J Biol Chem. 2025 Oct;301(10):110688. doi: 10.1016/j.jbc.2025.110688. Epub 2025 Sep 4. J Biol Chem. 2025. PMID: 40914250 Free PMC article.
The tRNA(Ile2) responsible for decoding this trinucleotide must be modified at the wobble position by tRNA(Ile) lysidine synthetase (TilS) prior to aminoacylation and accommodation at the ribosome. To test the hypothesis that TilS catalytic efficiency correlates wit …
The tRNA(Ile2) responsible for decoding this trinucleotide must be modified at the wobble position by tRNA(Ile) lysidine synthetase ( …
Problems in protein biosynthesis.
Lengyel P. Lengyel P. J Gen Physiol. 1966 Jul;49(6):305-30. doi: 10.1085/jgp.49.6.305. J Gen Physiol. 1966. PMID: 5338560 Free PMC article. Review.
Structure of the code: relatedness of synonym codons. The wobble hypothesis. Chain initiation and N-formyl-methionine. Chain termination and nonsense codons. ...
Structure of the code: relatedness of synonym codons. The wobble hypothesis. Chain initiation and N-formyl-methionine. Chain t …
Proto-Urea-RNA (Wöhler RNA) Containing Unusually Stable Urea Nucleosides.
Okamura H, Crisp A, Hübner S, Becker S, Rovó P, Carell T. Okamura H, et al. Angew Chem Int Ed Engl. 2019 Dec 16;58(51):18691-18696. doi: 10.1002/anie.201911746. Epub 2019 Oct 30. Angew Chem Int Ed Engl. 2019. PMID: 31573740 Free PMC article. Review.
The RNA world hypothesis assumes that life on Earth began with nucleotides that formed information-carrying RNA oligomers able to self-replicate. ...Investigations of the nucleotides' base-pairing potential showed that triuret:G RNA base pairs closely resemble U:G wobbl …
The RNA world hypothesis assumes that life on Earth began with nucleotides that formed information-carrying RNA oligomers able to sel …
Crick Wobble and Superwobble in Standard Genetic Code Evolution.
Yarus M. Yarus M. J Mol Evol. 2021 Feb;89(1-2):50-61. doi: 10.1007/s00239-020-09985-7. Epub 2021 Jan 7. J Mol Evol. 2021. PMID: 33409542 Free PMC article.
So, continuous superwobble is a very improbable origin hypothesis. In contrast, late-arising superwobble shares late Crick wobble's frequent resemblance to SGC order. Thus late superwobble is possible, but yields SGC-like assignments less frequently than late Crick …
So, continuous superwobble is a very improbable origin hypothesis. In contrast, late-arising superwobble shares late Crick wobble …
127 results