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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1948 2
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1958 1
1959 1
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1965 2
1966 1
1967 3
1969 4
1970 4
1971 3
1972 4
1973 4
1974 3
1975 3
1976 5
1977 10
1978 8
1979 8
1980 9
1981 2
1982 10
1983 11
1984 7
1985 7
1986 21
1987 13
1988 7
1989 9
1990 5
1991 10
1992 7
1993 15
1994 10
1995 12
1996 8
1997 10
1998 9
1999 17
2000 21
2001 22
2002 21
2003 24
2004 27
2005 22
2006 21
2007 20
2008 25
2009 35
2010 34
2011 28
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2013 35
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2022 52
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968 results
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Page 1
Wolfram Syndrome: Diagnosis, Management, and Treatment.
Urano F. Urano F. Curr Diab Rep. 2016 Jan;16(1):6. doi: 10.1007/s11892-015-0702-6. Curr Diab Rep. 2016. PMID: 26742931 Free PMC article. Review.
Wolfram syndrome is a rare genetic disorder characterized by juvenile-onset diabetes mellitus, diabetes insipidus, optic nerve atrophy, hearing loss, and neurodegeneration. ...The prognosis of this syndrome is currently poor, and many patients die prematurely
Wolfram syndrome is a rare genetic disorder characterized by juvenile-onset diabetes mellitus, diabetes insipidus, optic nerve
Wolfram syndrome, a rare neurodegenerative disease: from pathogenesis to future treatment perspectives.
Pallotta MT, Tascini G, Crispoldi R, Orabona C, Mondanelli G, Grohmann U, Esposito S. Pallotta MT, et al. J Transl Med. 2019 Jul 23;17(1):238. doi: 10.1186/s12967-019-1993-1. J Transl Med. 2019. PMID: 31337416 Free PMC article. Review.
BACKGROUND: Wolfram syndrome (WS), a rare genetic disorder, is considered the best prototype of endoplasmic reticulum (ER) diseases. ...
BACKGROUND: Wolfram syndrome (WS), a rare genetic disorder, is considered the best prototype of endoplasmic reticulum (ER) dis …
Clinical Spectrum Associated with Wolfram Syndrome Type 1 and Type 2: A Review on Genotype-Phenotype Correlations.
Delvecchio M, Iacoviello M, Pantaleo A, Resta N. Delvecchio M, et al. Int J Environ Res Public Health. 2021 Apr 30;18(9):4796. doi: 10.3390/ijerph18094796. Int J Environ Res Public Health. 2021. PMID: 33946243 Free PMC article. Review.
Wolfram syndrome is a rare neurodegenerative disorder that is typically characterized by diabetes mellitus and optic atrophy. ...The clinical presentation of Wolfram syndrome type 1 suggests that the pathogenic variant does not predict the phenotype. .
Wolfram syndrome is a rare neurodegenerative disorder that is typically characterized by diabetes mellitus and optic atrophy.
[Diabetes mellitus and optic atrophy: study of the Wolfram syndrome].
Rivas-Gómez B, Reza-Albarrán AA. Rivas-Gómez B, et al. Gac Med Mex. 2017;153(4):466-472. doi: 10.24875/GMM.17002396. Gac Med Mex. 2017. PMID: 28991271 Spanish.
BACKGROUND: Wolfram syndrome (WS), also known by the acronym DIDMOAD, is a rare and progresive hereditary disease of autosomal recessive inheritance which minimum ascertainment diagnostic criteria are the occurrence together of diabetes mellitus and optic atr …
BACKGROUND: Wolfram syndrome (WS), also known by the acronym DIDMOAD, is a rare and progresive hereditary disease of au …
Wolfram Syndrome 1: From Genetics to Therapy.
Rigoli L, Caruso V, Salzano G, Lombardo F. Rigoli L, et al. Int J Environ Res Public Health. 2022 Mar 9;19(6):3225. doi: 10.3390/ijerph19063225. Int J Environ Res Public Health. 2022. PMID: 35328914 Free PMC article. Review.
Wolfram syndrome 1 (WS1) is a rare neurodegenerative disease transmitted in an autosomal recessive mode. It is characterized by diabetes insipidus (DI), diabetes mellitus (DM), optic atrophy (OA), and sensorineural hearing loss (D) (DIDMOAD). The clinical pic
Wolfram syndrome 1 (WS1) is a rare neurodegenerative disease transmitted in an autosomal recessive mode. It is characterized b
Association of diabetes insipidus, diabetes mellitus, optic atrophy, and deafness. The Wolfram or DIDMOAD syndrome.
Najjar SS, Saikaly MG, Zaytoun GM, Abdelnoor A. Najjar SS, et al. Arch Dis Child. 1985 Sep;60(9):823-8. doi: 10.1136/adc.60.9.823. Arch Dis Child. 1985. PMID: 4051539 Free PMC article.
Seven patients with a rare syndrome of diabetes insipidus (DI), diabetes mellitus (DM), optic atrophy (OA), neurosensory deafness (D), atony of the urinary tract, and other abnormalities (Wolfram or DIDMOAD syndrome) are reported. ...A degenerative pro …
Seven patients with a rare syndrome of diabetes insipidus (DI), diabetes mellitus (DM), optic atrophy (OA), neurosensory deafness (D) …
Wolfram syndrome: Portuguese research.
Ferreras C, Gorito V, Pedro J, Ferreira S, Costa C, Santos Silva R, Castro Correia C. Ferreras C, et al. Endokrynol Pol. 2021;72(4):353-356. doi: 10.5603/EP.a2021.0038. Epub 2021 May 19. Endokrynol Pol. 2021. PMID: 34010437 Free article.
INTRODUCTION: Wolfram syndrome (WFS) is a neurological and endocrinological degenerative disorder, also known as DIDMOAD (Diabetes Insipidus, early-onset Diabetes Mellitus, progressive Optic Atrophy, and Deafness) syndrome. It is an autosomal recessive …
INTRODUCTION: Wolfram syndrome (WFS) is a neurological and endocrinological degenerative disorder, also known as DIDMOAD
Wolfram (DIDMOAD) syndrome and Leber hereditary optic neuropathy (LHON) are associated with distinct mitochondrial DNA haplotypes.
Hofmann S, Bezold R, Jaksch M, Obermaier-Kusser B, Mertens S, Kaufhold P, Rabl W, Hecker W, Gerbitz KD. Hofmann S, et al. Genomics. 1997 Jan 1;39(1):8-18. doi: 10.1006/geno.1996.4474. Genomics. 1997. PMID: 9027481
Because Wolfram (or DIDMOAD) syndrome is supposed to be a mitochondrial (mt)-mediated disease, we investigated a group of eight DIDMOAD patients with respect to point mutations of the mtDNA thus far described as being associated with defined mitochondr …
Because Wolfram (or DIDMOAD) syndrome is supposed to be a mitochondrial (mt)-mediated disease, we investigated a group …
Wolfram Syndrome presenting with optic atrophy and diabetes mellitus: two case reports.
Manaviat MR, Rashidi M, Mohammadi SM. Manaviat MR, et al. Cases J. 2009 Dec 19;2:9355. doi: 10.1186/1757-1626-2-9355. Cases J. 2009. PMID: 20062605 Free PMC article.
Wolfram syndrome is the constellation of juvenile onset diabetes mellitus and optic atrophy, known as DIDMOAD (Diabetes Insipidus, Diabetes Mellitus, Optic Atrophy, and Deafness).Patients demonstrate diabetes mellitus followed by optic atrophy in the first de
Wolfram syndrome is the constellation of juvenile onset diabetes mellitus and optic atrophy, known as DIDMOAD (Diabetes
968 results