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72,338 results

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Page 1
Scratch Wound Healing Assay.
Martinotti S, Ranzato E. Martinotti S, et al. Methods Mol Biol. 2020;2109:225-229. doi: 10.1007/7651_2019_259. Methods Mol Biol. 2020. PMID: 31414347
Cell migration is a crucial step for wound healing. Assays able to evaluate cell migration are very useful to evaluate in vitro wound healing. Scratch wound assay creates a gap in confluent monolayer of keratinocytes to mimic a …
Cell migration is a crucial step for wound healing. Assays able to evaluate cell migration are very useful to evaluate …
An introduction to the wound healing assay using live-cell microscopy.
Jonkman JE, Cathcart JA, Xu F, Bartolini ME, Amon JE, Stevens KM, Colarusso P. Jonkman JE, et al. Cell Adh Migr. 2014;8(5):440-51. doi: 10.4161/cam.36224. Cell Adh Migr. 2014. PMID: 25482647 Free PMC article.
The wound healing assay is used in a range of disciplines to study the coordinated movement of a cell population. In this technical review, we describe the workflow of the wound healing assay as monitored by optical microscopy. Although t …
The wound healing assay is used in a range of disciplines to study the coordinated movement of a cell population. In th …
Research Techniques Made Simple: Analysis of Collective Cell Migration Using the Wound Healing Assay.
Grada A, Otero-Vinas M, Prieto-Castrillo F, Obagi Z, Falanga V. Grada A, et al. J Invest Dermatol. 2017 Feb;137(2):e11-e16. doi: 10.1016/j.jid.2016.11.020. J Invest Dermatol. 2017. PMID: 28110712 Free article.
Wound healing is a complex cellular and biochemical process necessary to restore structurally damaged tissue. ...Although several methods exist to study cell migration (such as Boyden chamber assay, barrier assays, and microfluidics-based assays …
Wound healing is a complex cellular and biochemical process necessary to restore structurally damaged tissue. ...Although seve …
FGF21 promotes migration and differentiation of epidermal cells during wound healing via SIRT1-dependent autophagy.
Chen X, Tong G, Fan J, Shen Y, Wang N, Gong W, Hu Z, Zhu K, Li X, Jin L, Cong W, Xiao J, Zhu Z. Chen X, et al. Br J Pharmacol. 2022 Mar;179(5):1102-1121. doi: 10.1111/bph.15701. Epub 2021 Nov 16. Br J Pharmacol. 2022. PMID: 34608629 Free article.
BACKGROUND AND PURPOSE: Migration and differentiation of epidermal cells are essential for epidermal regeneration during wound healing. Fibroblast growth factor 21 (FGF21) plays key roles in mediating a variety of biological activities. However, its role in s …
BACKGROUND AND PURPOSE: Migration and differentiation of epidermal cells are essential for epidermal regeneration during wound hea …
An image J plugin for the high throughput image analysis of in vitro scratch wound healing assays.
Suarez-Arnedo A, Torres Figueroa F, Clavijo C, Arbeláez P, Cruz JC, Muñoz-Camargo C. Suarez-Arnedo A, et al. PLoS One. 2020 Jul 28;15(7):e0232565. doi: 10.1371/journal.pone.0232565. eCollection 2020. PLoS One. 2020. PMID: 32722676 Free PMC article.
In vitro scratch wound healing assay, a simple and low-cost technique that works along with other image analysis tools, is one of the most widely used 2D methods to determine the cellular migration and proliferation in processes such as regeneration an …
In vitro scratch wound healing assay, a simple and low-cost technique that works along with other image analysis …
Exosomes from human umbilical cord blood accelerate cutaneous wound healing through miR-21-3p-mediated promotion of angiogenesis and fibroblast function.
Hu Y, Rao SS, Wang ZX, Cao J, Tan YJ, Luo J, Li HM, Zhang WS, Chen CY, Xie H. Hu Y, et al. Theranostics. 2018 Jan 1;8(1):169-184. doi: 10.7150/thno.21234. eCollection 2018. Theranostics. 2018. PMID: 29290800 Free PMC article.
The efficacy of UCB-Exos on wound healing was evaluated by measuring wound closure rates, histological analysis and immunofluorescence examinations. In vitro, quantitative real-time PCR (qRT-PCR) analysis was performed to detect the expression l …
The efficacy of UCB-Exos on wound healing was evaluated by measuring wound closure rates, histological analysis …
Therapeutic candidates for keloid scars identified by qualitative review of scratch assay research for wound healing.
Alishahedani ME, Yadav M, McCann KJ, Gough P, Castillo CR, Matriz J, Myles IA. Alishahedani ME, et al. PLoS One. 2021 Jun 18;16(6):e0253669. doi: 10.1371/journal.pone.0253669. eCollection 2021. PLoS One. 2021. PMID: 34143844 Free PMC article. Review.
In the assay, cells are grown to confluence and then 'scratched' with a sterile instrument. For the cells in the leading edge, the resulting polarity induces migration and proliferation in attempt to 'heal' the modeled wound. Keloid scars are known to have an accele …
In the assay, cells are grown to confluence and then 'scratched' with a sterile instrument. For the cells in the leading edge, the re …
The In Vitro Wound-Scratch Assay: Applications, Technical Advances, and Limitations in Wound Healing Research.
Molefe PF, Ghasemishahrestani Z, Khumalo NP, Bayat A. Molefe PF, et al. Int Wound J. 2026 Jun;23(6):e70964. doi: 10.1111/iwj.70964. Int Wound J. 2026. PMID: 42226730 Free PMC article. Review.
While these advances enhance technical consistency, they do not overcome the assay's fundamental biological constraints. Importantly, gap closure in the wound-scratch assay primarily reflects planar collective cell migration and does not recapit …
While these advances enhance technical consistency, they do not overcome the assay's fundamental biological constraints …
A Wound-Healing Assay Based on Ultraviolet Light Ablation.
Wu SY, Sun YS, Cheng KC, Lo KY. Wu SY, et al. SLAS Technol. 2017 Feb;22(1):36-43. doi: 10.1177/2211068216646741. Epub 2016 Jul 10. SLAS Technol. 2017. PMID: 27139694 Free article.
These assays are useful tools in studying the effects of certain physical or chemical stimuli on the wound-healing process. ...The advantages of this UV-created wound-healing assay include fast and easy procedure, high throughput, and no …
These assays are useful tools in studying the effects of certain physical or chemical stimuli on the wound-healing proc …
A microfabricated 96-well wound-healing assay.
Luan S, Hao R, Wei Y, Chen D, Fan B, Dong F, Guo W, Wang J, Chen J. Luan S, et al. Cytometry A. 2017 Dec;91(12):1192-1199. doi: 10.1002/cyto.a.23286. Epub 2017 Nov 20. Cytometry A. 2017. PMID: 29156109 Free article.
This article presents a microfabricated 96-well wound-healing assay enabling high-throughput measurement of cellular migration capabilities. ...Furthermore, the migration capabilities of a second cell type (HeLa) were characterized by the developed wound …
This article presents a microfabricated 96-well wound-healing assay enabling high-throughput measurement of cellular mi …
72,338 results
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