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Page 1
Xanthohumol: A Metabolite with Promising Anti-Neoplastic Potential.
Tuli HS, Aggarwal V, Parashar G, Aggarwal D, Parashar NC, Tuorkey MJ, Varol M, Sak K, Kumar M, Buttar HS. Tuli HS, et al. Anticancer Agents Med Chem. 2022;22(3):418-432. doi: 10.2174/1871520621666210223095021. Anticancer Agents Med Chem. 2022. PMID: 33622230 Review.
In the last decade, xanthohumol has been investigated how it induces the anti- cancer effects at cellular and molecular levels. The different signalling cascades and targets of xanthohumol are summarized in this review. Overall, this review summarizes the current ad …
In the last decade, xanthohumol has been investigated how it induces the anti- cancer effects at cellular and molecular levels. The d …
Xanthohumol properties and strategies for extraction from hops and brewery residues: A review.
Vicente de Andrade Silva G, Demaman Arend G, Antonio Ferreira Zielinski A, Di Luccio M, Ambrosi A. Vicente de Andrade Silva G, et al. Food Chem. 2023 Mar 15;404(Pt B):134629. doi: 10.1016/j.foodchem.2022.134629. Epub 2022 Oct 17. Food Chem. 2023. PMID: 36283308 Review.
Xanthohumol, a chalcone unique to hops, has attracted attention from researchers due to its several pharmacological effects on humans. In industry, hops are almost exclusively used in beer production, generating tons of solid waste - hot trub from the boiling step and spen
Xanthohumol, a chalcone unique to hops, has attracted attention from researchers due to its several pharmacological effects on humans
Xanthohumol from Hop: Hope for cancer prevention and treatment.
Girisa S, Saikia Q, Bordoloi D, Banik K, Monisha J, Daimary UD, Verma E, Ahn KS, Kunnumakkara AB. Girisa S, et al. IUBMB Life. 2021 Aug;73(8):1016-1044. doi: 10.1002/iub.2522. Epub 2021 Jul 6. IUBMB Life. 2021. PMID: 34170599 Free article. Review.
The factors such as drug resistance, lack of specificity, and low efficacy of the cancer drugs necessitate developing alternative strategies for the prevention and treatment of this disease. Xanthohumol (XN), a prenylated chalcone present in Hop (Humulus lupulus), has been …
The factors such as drug resistance, lack of specificity, and low efficacy of the cancer drugs necessitate developing alternative strategies …
Xanthohumol ameliorates drug-induced hepatic ferroptosis via activating Nrf2/xCT/GPX4 signaling pathway.
Deng Y, Chu X, Li Q, Zhu G, Hu J, Sun J, Zeng H, Huang J, Ge G. Deng Y, et al. Phytomedicine. 2024 Apr;126:155458. doi: 10.1016/j.phymed.2024.155458. Epub 2024 Feb 22. Phytomedicine. 2024. PMID: 38394733
Previous studies have demonstrated that xanthohumol (Xh), a natural prenylflavonoid isolated from hops, exhibits anti-inflammatory, anti-antioxidative and hepatoprotective properties. ...
Previous studies have demonstrated that xanthohumol (Xh), a natural prenylflavonoid isolated from hops, exhibits anti-inflammatory, a …
Xanthohumol for Human Malignancies: Chemistry, Pharmacokinetics and Molecular Targets.
Harish V, Haque E, Śmiech M, Taniguchi H, Jamieson S, Tewari D, Bishayee A. Harish V, et al. Int J Mol Sci. 2021 Apr 25;22(9):4478. doi: 10.3390/ijms22094478. Int J Mol Sci. 2021. PMID: 33923053 Free PMC article. Review.
Xanthohumol (XH) is an important prenylated flavonoid that is found within the inflorescence of Humulus lupulus L. ...
Xanthohumol (XH) is an important prenylated flavonoid that is found within the inflorescence of Humulus lupulus L. ...
Xanthohumol protect against acetaminophen-induced hepatotoxicity via Nrf2 activation through the AMPK/Akt/GSK3beta pathway.
Zhu L, Fan X, Cao C, Li K, Hou W, Ci X. Zhu L, et al. Biomed Pharmacother. 2023 Sep;165:115097. doi: 10.1016/j.biopha.2023.115097. Epub 2023 Jul 3. Biomed Pharmacother. 2023. PMID: 37406514 Free article.
RESULTS: In vitro, xanthohumol inhibited H(2)O(2)- and acetaminophen-induced cytotoxicity and oxidative stress. Xanthohumol up-regulated the expression of Nrf2. Further mechanistic studies showed that xanthohumol triggered Nrf2 activation via the AMPK/Akt/GSK …
RESULTS: In vitro, xanthohumol inhibited H(2)O(2)- and acetaminophen-induced cytotoxicity and oxidative stress. Xanthohumol up …
Xanthohumol: An underestimated, while potent and promising chemotherapeutic agent in cancer treatment.
Vesaghhamedani S, Ebrahimzadeh F, Najafi E, Shabgah OG, Askari E, Shabgah AG, Mohammadi H, Jadidi-Niaragh F, Navashenaq JG. Vesaghhamedani S, et al. Prog Biophys Mol Biol. 2022 Aug;172:3-14. doi: 10.1016/j.pbiomolbio.2022.04.002. Epub 2022 Apr 8. Prog Biophys Mol Biol. 2022. PMID: 35405185 Review.
Today, there is a growing interest nowadays in the use of herbal substances as cancer therapeutic agents. Over recent years, Xanthohumol (XTL) has been brought out as a prenylated chalcone that is found in hops (Humulus lupulus) and beer. ...
Today, there is a growing interest nowadays in the use of herbal substances as cancer therapeutic agents. Over recent years, Xanthohumol
Bioavailability and Cardiometabolic Effects of Xanthohumol: Evidence from Animal and Human Studies.
Neumann HF, Frank J, Venturelli S, Egert S. Neumann HF, et al. Mol Nutr Food Res. 2022 Mar;66(6):e2100831. doi: 10.1002/mnfr.202100831. Epub 2022 Jan 14. Mol Nutr Food Res. 2022. PMID: 34967501 Review.
In addition, it provides insights into the pharmacokinetics of xanthohumol intake. Animal studies show that xanthohumol exerts beneficial effects on body weight, lipid profile, glucose metabolism, and other biochemical parameters associated with metabolic syndrome a …
In addition, it provides insights into the pharmacokinetics of xanthohumol intake. Animal studies show that xanthohumol exerts …
Xanthohumol inhibits non-small cell lung cancer by activating PUMA-mediated apoptosis.
Li X, Jin L, Ma Y, Jiang Z, Tang H, Tong X. Li X, et al. Toxicology. 2022 Mar 30;470:153141. doi: 10.1016/j.tox.2022.153141. Epub 2022 Mar 5. Toxicology. 2022. PMID: 35259468 Free article.
Here, we have investigated the potency of Xanthohumol against NSCLC cells in vitro and xenograft mouse models. Xanthohumol suppressed cell viability, colony formation and induced apoptosis in A549, H520, and H358 cells. ...Silent PUMA or FOXO3a impaired Xanthohum
Here, we have investigated the potency of Xanthohumol against NSCLC cells in vitro and xenograft mouse models. Xanthohumol sup …
Xanthohumol improves cognitive impairment by regulating miRNA-532-3p/Mpped1 in ovariectomized mice.
Liu Y, Shao J, Qiao R, Li J, Li C, Cao W. Liu Y, et al. Psychopharmacology (Berl). 2023 May;240(5):1169-1178. doi: 10.1007/s00213-023-06355-1. Epub 2023 Mar 20. Psychopharmacology (Berl). 2023. PMID: 36939856
RATIONALE: Studies have shown the potential neuroprotective effect of xanthohumol, while whether xanthohumol has the ability of repairing cognitive impairment and its underlying mechanism still remains obscure. ...Increased miR-532-3p in OVX mice was suppressed by …
RATIONALE: Studies have shown the potential neuroprotective effect of xanthohumol, while whether xanthohumol has the ability o …
743 results