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Novel anti-obesity effects of beer hops compound xanthohumol: role of AMPK signaling pathway.
Samuels JS, Shashidharamurthy R, Rayalam S. Samuels JS, et al. Nutr Metab (Lond). 2018 Jun 15;15:42. doi: 10.1186/s12986-018-0277-8. eCollection 2018. Nutr Metab (Lond). 2018. PMID: 29946343 Free PMC article.
CONCLUSIONS: Taken together, XN demonstrates anti-obesity effects by not only inducing beiging but also decreasing adipogenesis and inducing lipolysis. The anti-obesity effects of XN are partly mediated by AMPK signaling pathway suggesting that XN may …
CONCLUSIONS: Taken together, XN demonstrates anti-obesity effects by not only inducing beiging but also decreasing adipogenesi …
A metabolomics-driven elucidation of the anti-obesity mechanisms of xanthohumol.
Kirkwood JS, Legette LL, Miranda CL, Jiang Y, Stevens JF. Kirkwood JS, et al. J Biol Chem. 2013 Jun 28;288(26):19000-13. doi: 10.1074/jbc.M112.445452. Epub 2013 May 14. J Biol Chem. 2013. PMID: 23673658 Free PMC article.
Together, these strategies target energy imbalance and oxidative stress, both underlying factors of obesity and related conditions such as type 2 diabetes. Here we describe a metabolomics-driven effort to uncover the anti-obesity mechanism(s) of xanthohumo …
Together, these strategies target energy imbalance and oxidative stress, both underlying factors of obesity and related conditions su …
Anti-obesity effects of xanthohumol plus guggulsterone in 3T3-L1 adipocytes.
Rayalam S, Yang JY, Della-Fera MA, Park HJ, Ambati S, Baile CA. Rayalam S, et al. J Med Food. 2009 Aug;12(4):846-53. doi: 10.1089/jmf.2008.0158. J Med Food. 2009. PMID: 19735186
Xanthohumol (XN) and guggulsterone (GS) have each been shown to inhibit adipogenesis and induce apoptosis in adipocytes. In the present study effects of the combination of XN + GS on 3T3-L1 adipocyte apoptosis and adipogenesis were investigated. ...Thus, combination of XN …
Xanthohumol (XN) and guggulsterone (GS) have each been shown to inhibit adipogenesis and induce apoptosis in adipocytes. In the prese …
Effect of Dietary Purified Xanthohumol from Hop (Humulus lupulus L.) Pomace on Adipose Tissue Mass, Fasting Blood Glucose Level, and Lipid Metabolism in KK-Ay Mice.
Takahashi K, Osada K. Takahashi K, et al. J Oleo Sci. 2017 May 1;66(5):531-541. doi: 10.5650/jos.ess16234. Epub 2017 Apr 13. J Oleo Sci. 2017. PMID: 28413193 Free article.
We previously showed that xanthohumol-rich hop extract (XRHE, ~18% xanthohumol) exerts anti-obesity effects in rats fed a high-fat diet through regulation of fatty acid metabolism. ...Thus, we found that PX may exert anti-obesity effects …
We previously showed that xanthohumol-rich hop extract (XRHE, ~18% xanthohumol) exerts anti-obesity effects in r …
Xanthohumol Inhibits the Growth of Keratin 18-Overexpressed Esophageal Squamous Cell Carcinoma in vitro and in vivo.
Yin S, Song M, Zhao R, Liu X, Kang WK, Lee JM, Kim YE, Zhang C, Shim JH, Liu K, Dong Z, Lee MH. Yin S, et al. Front Cell Dev Biol. 2020 May 19;8:366. doi: 10.3389/fcell.2020.00366. eCollection 2020. Front Cell Dev Biol. 2020. PMID: 32509787 Free PMC article.
Xanthohumol is a prenylated flavonoid isolated from hops. Although xanthohumol has been reported to exert anti-obesity, hypoglycemic, anti-hyperlipidemia and anti-cancer activities, the mechanisms underlying its chemotherapeutic activity …
Xanthohumol is a prenylated flavonoid isolated from hops. Although xanthohumol has been reported to exert anti-obesi …
Chalcones as putative hepatoprotective agents: Preclinical evidence and molecular mechanisms.
Karimi-Sales E, Mohaddes G, Alipour MR. Karimi-Sales E, et al. Pharmacol Res. 2018 Mar;129:177-187. doi: 10.1016/j.phrs.2017.11.022. Epub 2017 Nov 23. Pharmacol Res. 2018. PMID: 29175112 Review.
These compounds have many beneficial properties including anti-inflammatory, anti-microbial, antioxidant, anti-cancer, anti-amyloid, anti-diabetic, anti-obesity, hypolipidemic, and cytoprotective. ...In conclusion, chalcones with a …
These compounds have many beneficial properties including anti-inflammatory, anti-microbial, antioxidant, anti-cancer, …
Effects of xanthohumol-rich hop extract on the differentiation of preadipocytes.
Kiyofuji A, Yui K, Takahashi K, Osada K. Kiyofuji A, et al. J Oleo Sci. 2014;63(6):593-7. doi: 10.5650/jos.ess14009. Epub 2014 May 15. J Oleo Sci. 2014. PMID: 24829131 Free article.
Xanthohumol is a major prenylated, hydrophobic flavonoid found in the female inflorescences of the hop plant (Humulus lupulus L.). In this study, we examined the effects of xanthohumol-rich hop extract containing 17.8% xanthohumol and 12.4% isoxanthohumol on …
Xanthohumol is a major prenylated, hydrophobic flavonoid found in the female inflorescences of the hop plant (Humulus lupulus L.). In …
Effects of xanthohumol-rich extract from the hop on fatty acid metabolism in rats fed a high-fat diet.
Yui K, Kiyofuji A, Osada K. Yui K, et al. J Oleo Sci. 2014;63(2):159-68. doi: 10.5650/jos.ess13136. Epub 2014 Jan 14. J Oleo Sci. 2014. PMID: 24420065 Free article.
We examined the effects of dietary xanthohumol-rich hop extract in obese rats that was induced by feeding a high-fat diet. Dietary xanthohumol-rich hop extract significantly lowered the body weight gain of these rats compared to rats fed a high-fat diet without the …
We examined the effects of dietary xanthohumol-rich hop extract in obese rats that was induced by feeding a high-fat diet. Dietary …
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