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A Novel Look at Mechanisms and Applications of Xanthohumol (XN) in Dermatology and Cosmetology.
Kołodziejczak A, Dziedzic M, Algiert-Zielińska B, Mucha P, Rotsztejn H. Kołodziejczak A, et al. Int J Mol Sci. 2024 Nov 6;25(22):11938. doi: 10.3390/ijms252211938. Int J Mol Sci. 2024. PMID: 39596008 Free PMC article. Review.
Xanthohumol (XN), representing the group of chalcones, is a hydroxyl and superoxide free radical scavenger. It also has antimicrobial properties, showing antibacterial activity against Staphylococcus aureus, Staphylococcus pyogenes, Staphylococcus epidermidis and Pr
Xanthohumol (XN), representing the group of chalcones, is a hydroxyl and superoxide free radical scavenger. It also has antimicrobial
The Antimicrobial Activity of Curcumin and Xanthohumol on Bacterial Biofilms Developed over Dental Implant Surfaces.
Alonso-Español A, Bravo E, Ribeiro-Vidal H, Virto L, Herrera D, Alonso B, Sanz M. Alonso-Español A, et al. Int J Mol Sci. 2023 Jan 25;24(3):2335. doi: 10.3390/ijms24032335. Int J Mol Sci. 2023. PMID: 36768657 Free PMC article.
The antimicrobial activities of curcumin (5 mM) and xanthohumol (100 muM) extracts, and the respective controls, were evaluated with 72-h biofilms formed over dental implants by their submersion for 60 seconds. ...It was concluded that both curcumin and xanthohumol
The antimicrobial activities of curcumin (5 mM) and xanthohumol (100 muM) extracts, and the respective controls, were evaluated with …
Xanthohumol prolongs lifespan and decreases stress-induced mortality in Drosophila melanogaster.
Wongchum N, Dechakhamphu A. Wongchum N, et al. Comp Biochem Physiol C Toxicol Pharmacol. 2021 Jun;244:108994. doi: 10.1016/j.cbpc.2021.108994. Epub 2021 Feb 4. Comp Biochem Physiol C Toxicol Pharmacol. 2021. PMID: 33549830
Drosophila or fruit fly is one of the most effective models for the evaluation of anti-aging compounds. Xanthohumol (XN) is a potential bioactive substance for the prevention and treatment of many diseases. The previous studies have reported its potent activities as antiox …
Drosophila or fruit fly is one of the most effective models for the evaluation of anti-aging compounds. Xanthohumol (XN) is a potenti …
Identification of colupulone and lupulone as the main contributors to the antibacterial activity of hop extracts using activity-guided fractionation and metabolome analysis.
Li Y, Dalabasmaz S, Gensberger-Reigl S, Heymich ML, Krofta K, Pischetsrieder M. Li Y, et al. Food Res Int. 2023 Jul;169:112832. doi: 10.1016/j.foodres.2023.112832. Epub 2023 Apr 17. Food Res Int. 2023. PMID: 37254407
Activity-guided fractionation revealed the highest antibacterial activity for lupulone and adlupulone (MIC 0.98 g/mL). Metabolome profiling and subsequent multistep statistical analysis detected 33 metabolites out of 1826 features to be associated with the antibacterial
Activity-guided fractionation revealed the highest antibacterial activity for lupulone and adlupulone (MIC 0.98 g/mL). Metabolome pro …
Xanthohumol from Humulus lupulus L. potentiates the killing of Mycobacterium tuberculosis and mitigates liver toxicity by the combination of isoniazid in mouse tuberculosis models.
Lou H, Zhang F, Lu L, Ding Y, Hao X. Lou H, et al. RSC Adv. 2020 Apr 1;10(22):13223-13231. doi: 10.1039/c9ra10347c. eCollection 2020 Mar 30. RSC Adv. 2020. PMID: 35492081 Free PMC article.
Anti-tuberculosis drug induced hepatotoxicity is the main problem in tuberculosis patients. Xanthohumol, a major prenyl chalcone present in hops, has diverse biological activities including antibacterial and hepatoprotective activities. ...In conclusion, xanthohu
Anti-tuberculosis drug induced hepatotoxicity is the main problem in tuberculosis patients. Xanthohumol, a major prenyl chalcone pres …
Prenylated Flavonoids in Topical Infections and Wound Healing.
Sychrová A, Škovranová G, Čulenová M, Bittner Fialová S. Sychrová A, et al. Molecules. 2022 Jul 13;27(14):4491. doi: 10.3390/molecules27144491. Molecules. 2022. PMID: 35889363 Free PMC article. Review.
The review presents prenylated flavonoids as potential therapeutic agents for the treatment of topical skin infections and wounds, as they can restore the balance in the wound microenvironment. ...A total of 127 structurally diverse flavonoids showed promising antimicrobia …
The review presents prenylated flavonoids as potential therapeutic agents for the treatment of topical skin infections and wounds, as …
Bioactive Compounds Obtained from Polish "Marynka" Hop Variety Using Efficient Two-Step Supercritical Fluid Extraction and Comparison of Their Antibacterial, Cytotoxic, and Anti-Proliferative Activities In Vitro.
Klimek K, Tyśkiewicz K, Miazga-Karska M, Dębczak A, Rój E, Ginalska G. Klimek K, et al. Molecules. 2021 Apr 19;26(8):2366. doi: 10.3390/molecules26082366. Molecules. 2021. PMID: 33921703 Free PMC article.
Then, both samples were subjected to investigation of their antibacterial (anti-acne, anti-caries), cytotoxic, and anti-proliferative activities in vitro. It was demonstrated that extract (E1) possessed more beneficial biological properties than xanthohumol. It exhi …
Then, both samples were subjected to investigation of their antibacterial (anti-acne, anti-caries), cytotoxic, and anti-proliferative …
Antiproliferative and palliative activity of flavonoids in colorectal cancer.
Fernández J, Silván B, Entrialgo-Cadierno R, Villar CJ, Capasso R, Uranga JA, Lombó F, Abalo R. Fernández J, et al. Biomed Pharmacother. 2021 Nov;143:112241. doi: 10.1016/j.biopha.2021.112241. Epub 2021 Sep 30. Biomed Pharmacother. 2021. PMID: 34649363 Free article. Review.
Flavonoids are plant bioactive compounds of great interest in nutrition and pharmacology, due to their remarkable properties as antioxidant, anti-inflammatory, antibacterial, antifungal and antitumor drugs. More than 5000 different flavonoids exist in nature, with a huge s …
Flavonoids are plant bioactive compounds of great interest in nutrition and pharmacology, due to their remarkable properties as antioxidant, …
Strong antimicrobial activity of xanthohumol and other derivatives from hops (Humulus lupulus L.) on gut anaerobic bacteria.
Cermak P, Olsovska J, Mikyska A, Dusek M, Kadleckova Z, Vanicek J, Nyc O, Sigler K, Bostikova V, Bostik P. Cermak P, et al. APMIS. 2017 Nov;125(11):1033-1038. doi: 10.1111/apm.12747. Epub 2017 Sep 28. APMIS. 2017. PMID: 28960474
Hops (Humulus lupulus L.) contain substances with antibacterial properties. We tested antimicrobial activity of purified hop constituents humulone, lupulone and xanthohumol against anaerobic bacteria. ...Strongest antimicrobial effects were observed with xanthohu
Hops (Humulus lupulus L.) contain substances with antibacterial properties. We tested antimicrobial activity of purified hop constitu …
Role of Characteristic Components of Humulus lupulus in Promoting Human Health.
Lin M, Xiang D, Chen X, Huo H. Lin M, et al. J Agric Food Chem. 2019 Jul 31;67(30):8291-8302. doi: 10.1021/acs.jafc.9b03780. Epub 2019 Jul 18. J Agric Food Chem. 2019. PMID: 31287692 Review.
Among them, Humulus lupulus has attracted special attention throughout the world because it contains numerous dietary phytochemicals that not only contribute to the aroma and flavor of beer but may also be used for medicinal purposes, as its properties include antiseptic, (an)aph …
Among them, Humulus lupulus has attracted special attention throughout the world because it contains numerous dietary phytochemicals that no …
33 results