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2000 1
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2003 2
2004 1
2005 4
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2007 8
2008 7
2009 6
2010 8
2011 6
2012 4
2013 10
2014 5
2015 8
2016 10
2017 12
2018 11
2019 14
2020 19
2021 18
2022 6
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139 results
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The Cancer Prevention, Anti-Inflammatory and Anti-Oxidation of Bioactive Phytochemicals Targeting the TLR4 Signaling Pathway.
Chen CY, Kao CL, Liu CM. Chen CY, et al. Int J Mol Sci. 2018 Sep 12;19(9):2729. doi: 10.3390/ijms19092729. Int J Mol Sci. 2018. PMID: 30213077 Free PMC article. Review.
Curcumin, 6-gingerol, 6-shogaol, 1-dehydro-10-gingerdione, epigallocatechin gallate (EGCG), luteolin, quercetin, resveratrol, caffeic acid phenethyl ester, xanthohumol, genistein, berberine, and sulforaphane can inhibit TLR4 activation. ...
Curcumin, 6-gingerol, 6-shogaol, 1-dehydro-10-gingerdione, epigallocatechin gallate (EGCG), luteolin, quercetin, resveratrol, caffeic acid p …
Xanthohumol ameliorates lipopolysaccharide (LPS)-induced acute lung injury via induction of AMPK/GSK3β-Nrf2 signal axis.
Lv H, Liu Q, Wen Z, Feng H, Deng X, Ci X. Lv H, et al. Redox Biol. 2017 Aug;12:311-324. doi: 10.1016/j.redox.2017.03.001. Epub 2017 Mar 2. Redox Biol. 2017. PMID: 28285192 Free PMC article.
Abundant natural flavonoids can induce nuclear factor-erythroid 2 related factor 2 (Nrf2) and/or AMP-activated protein kinase (AMPK) activation, which play crucial roles in the amelioration of various inflammation- and oxidative stress-induced diseases, including acute lung injur …
Abundant natural flavonoids can induce nuclear factor-erythroid 2 related factor 2 (Nrf2) and/or AMP-activated protein kinase (AMPK) activat …
Xanthohumol for Human Malignancies: Chemistry, Pharmacokinetics and Molecular Targets.
Harish V, Haque E, Śmiech M, Taniguchi H, Jamieson S, Tewari D, Bishayee A. Harish V, et al. Int J Mol Sci. 2021 Apr 25;22(9):4478. doi: 10.3390/ijms22094478. Int J Mol Sci. 2021. PMID: 33923053 Free PMC article. Review.
Xanthohumol (XH) is an important prenylated flavonoid that is found within the inflorescence of Humulus lupulus L. ...XH is an important ingredient in beer and is considered a significant bioactive agent due to its diverse medicinal applications, which include anti-inflamm
Xanthohumol (XH) is an important prenylated flavonoid that is found within the inflorescence of Humulus lupulus L. ...XH is an import
Xanthohumol prolongs lifespan and decreases stress-induced mortality in Drosophila melanogaster.
Wongchum N, Dechakhamphu A. Wongchum N, et al. Comp Biochem Physiol C Toxicol Pharmacol. 2021 Jun;244:108994. doi: 10.1016/j.cbpc.2021.108994. Epub 2021 Feb 4. Comp Biochem Physiol C Toxicol Pharmacol. 2021. PMID: 33549830
Drosophila or fruit fly is one of the most effective models for the evaluation of anti-aging compounds. Xanthohumol (XN) is a potential bioactive substance for the prevention and treatment of many diseases. The previous studies have reported its potent activities as ant
Drosophila or fruit fly is one of the most effective models for the evaluation of anti-aging compounds. Xanthohumol (XN) is a potenti …
Modulation of Adenosine Receptors by Hops and Xanthohumol in Cell Cultures.
Alonso P, Albasanz JL, Martín M. Alonso P, et al. ACS Chem Neurosci. 2021 Jul 7;12(13):2373-2384. doi: 10.1021/acschemneuro.1c00130. Epub 2021 Jun 22. ACS Chem Neurosci. 2021. PMID: 34156813
The present work aimed to analyze the possible protective effect of hops (Humulus lupulus L.), a major component of beer, and xanthohumol on cell death elicited by oxidative stress and their modulation of ARs in rat C6 glioma and human SH-SY5Y neuroblastoma cells. ...Cell …
The present work aimed to analyze the possible protective effect of hops (Humulus lupulus L.), a major component of beer, and xanthohumol
Xanthohumol suppresses inflammation in chondrocytes and ameliorates osteoarthritis in mice.
Chen X, Li Z, Hong H, Wang N, Chen J, Lu S, Zhang H, Zhang X, Bei C. Chen X, et al. Biomed Pharmacother. 2021 May;137:111238. doi: 10.1016/j.biopha.2021.111238. Epub 2021 Jan 28. Biomed Pharmacother. 2021. PMID: 33517187 Free article.
In various maladies, an anti-inflammatory effect has been demonstrated for Xanthohumol (XN); while OA is an inflammation related disease. The current in vivo and in vitro study aimed to investigate the therapeutic effect of XN on OA as well as its working mechanism. ...
In various maladies, an anti-inflammatory effect has been demonstrated for Xanthohumol (XN); while OA is an inflammation related dise …
Plants as source of new therapies for endometriosis: a review of preclinical and clinical studies.
Meresman GF, Götte M, Laschke MW. Meresman GF, et al. Hum Reprod Update. 2021 Feb 19;27(2):367-392. doi: 10.1093/humupd/dmaa039. Hum Reprod Update. 2021. PMID: 33124671 Review.
The most studied specific plant-derived bioactive compounds are resveratrol, epigallocatechin-3-gallate, curcumin, puerarin, ginsenosides, xanthohumol, 4-hydroxybenzyl alcohol, quercetin, apigenin, carnosic acid, rosmarinic acid, wogonin, baicalein, parthenolide, andrograp …
The most studied specific plant-derived bioactive compounds are resveratrol, epigallocatechin-3-gallate, curcumin, puerarin, ginsenosides, …
Synthesis and antioxidant evaluation of desmethylxanthohumol analogs and their dimers.
Teng Y, Li X, Yang K, Li X, Zhang Z, Wang L, Deng Z, Song B, Yan Z, Zhang Y, Lu K, Yu P. Teng Y, et al. Eur J Med Chem. 2017 Jan 5;125:335-345. doi: 10.1016/j.ejmech.2016.09.024. Epub 2016 Sep 13. Eur J Med Chem. 2017. PMID: 27688188
The structures of the eight new derivatives were confirmed using(1)H NMR, (13)C NMR and HRMS. The antioxidant activity of the new chalcone derivatives were evaluated in a PC12 cell model of H(2)O(2)-induced oxidative damage. The SAR studies suggested that the catechol moti …
The structures of the eight new derivatives were confirmed using(1)H NMR, (13)C NMR and HRMS. The antioxidant activity of the new cha …
Controlled release of resveratrol and xanthohumol via coaxial electrospinning fibers.
Zhang X, Han L, Sun Q, Xia W, Zhou Q, Zhang Z, Song X. Zhang X, et al. J Biomater Sci Polym Ed. 2020 Mar;31(4):456-471. doi: 10.1080/09205063.2019.1700600. Epub 2019 Dec 17. J Biomater Sci Polym Ed. 2020. PMID: 31801405
Synergistic delivery of two drugs is a desirable choice to overcome drug resistance. Resveratrol (RES) and xanthohumol (XAN) which are both new drugs originated from plants exhibit great potential in the treatment of cancer, but there are few studies on combining them in a …
Synergistic delivery of two drugs is a desirable choice to overcome drug resistance. Resveratrol (RES) and xanthohumol (XAN) which ar …
Xanthohumol and 8-prenylnaringenin reduce type 2 diabetes-associated oxidative stress by downregulating galectin-3.
Luís C, Costa R, Rodrigues I, Castela Â, Coelho P, Guerreiro S, Gomes J, Reis C, Soares R. Luís C, et al. Porto Biomed J. 2018 Aug 8;4(1):e23. doi: 10.1016/j.pbj.0000000000000023. eCollection 2019 Jan-Feb. Porto Biomed J. 2018. PMID: 31595252 Free PMC article.
METHODS: Herein, we examined the interplay between Gal3 and oxidative stress in a high-fat diet -induced type 2 DMC57Bl/6 mice model. Because natural polyphenols are known to play antioxidant and anti-inflammatory roles and to modulate metabolic activity, we further evalua …
METHODS: Herein, we examined the interplay between Gal3 and oxidative stress in a high-fat diet -induced type 2 DMC57Bl/6 mice model. Becaus …
139 results