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2004 2
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2008 2
2009 2
2010 2
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2014 1
2015 3
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2021 3
2022 1
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Xanthohumol for Human Malignancies: Chemistry, Pharmacokinetics and Molecular Targets.
Harish V, Haque E, Śmiech M, Taniguchi H, Jamieson S, Tewari D, Bishayee A. Harish V, et al. Int J Mol Sci. 2021 Apr 25;22(9):4478. doi: 10.3390/ijms22094478. Int J Mol Sci. 2021. PMID: 33923053 Free PMC article. Review.
Xanthohumol (XH) is an important prenylated flavonoid that is found within the inflorescence of Humulus lupulus L. ...XH is an important ingredient in beer and is considered a significant bioactive agent due to its diverse medicinal applications, which include anti-inflamm
Xanthohumol (XH) is an important prenylated flavonoid that is found within the inflorescence of Humulus lupulus L. ...XH is an import
Xanthohumol prolongs lifespan and decreases stress-induced mortality in Drosophila melanogaster.
Wongchum N, Dechakhamphu A. Wongchum N, et al. Comp Biochem Physiol C Toxicol Pharmacol. 2021 Jun;244:108994. doi: 10.1016/j.cbpc.2021.108994. Epub 2021 Feb 4. Comp Biochem Physiol C Toxicol Pharmacol. 2021. PMID: 33549830
Drosophila or fruit fly is one of the most effective models for the evaluation of anti-aging compounds. Xanthohumol (XN) is a potential bioactive substance for the prevention and treatment of many diseases. The previous studies have reported its potent activities as antiox …
Drosophila or fruit fly is one of the most effective models for the evaluation of anti-aging compounds. Xanthohumol (XN) is a potenti …
Xanthohumol Is a Potent Pan-Inhibitor of Coronaviruses Targeting Main Protease.
Lin Y, Zang R, Ma Y, Wang Z, Li L, Ding S, Zhang R, Wei Z, Yang J, Wang X. Lin Y, et al. Int J Mol Sci. 2021 Nov 9;22(22):12134. doi: 10.3390/ijms222212134. Int J Mol Sci. 2021. PMID: 34830015 Free PMC article.
The main protease (M(pro)) of coronavirus plays a pivotal role in viral replication and transcription, which, in theory, is an attractive drug target for antiviral drug development. It has been extensively discussed whether Xanthohumol is able to help COVID-19 patie …
The main protease (M(pro)) of coronavirus plays a pivotal role in viral replication and transcription, which, in theory, is an attractive dr …
Xanthohumol: An underestimated, while potent and promising chemotherapeutic agent in cancer treatment.
Vesaghhamedani S, Ebrahimzadeh F, Najafi E, Shabgah OG, Askari E, Shabgah AG, Mohammadi H, Jadidi-Niaragh F, Navashenaq JG. Vesaghhamedani S, et al. Prog Biophys Mol Biol. 2022 Apr 8:S0079-6107(22)00031-1. doi: 10.1016/j.pbiomolbio.2022.04.002. Online ahead of print. Prog Biophys Mol Biol. 2022. PMID: 35405185 Review.
Today, there is a growing interest nowadays in the use of herbal substances as cancer therapeutic agents. Over recent years, Xanthohumol (XTL) has been brought out as a prenylated chalcone that is found in hops (Humulus lupulus) and beer. ...Additionally, XTL deriva …
Today, there is a growing interest nowadays in the use of herbal substances as cancer therapeutic agents. Over recent years, Xanth
Anticancer effect of xanthohumol induces growth inhibition and apoptosis of human liver cancer through NF-κB/p53-apoptosis signaling pathway.
Zhao X, Jiang K, Liang B, Huang X. Zhao X, et al. Oncol Rep. 2016 Feb;35(2):669-75. doi: 10.3892/or.2015.4455. Epub 2015 Nov 26. Oncol Rep. 2016. PMID: 26718026 Free PMC article.
Xanthohumol may prevent and cure diabetes and atherosis, have oxidation resistance and antiviral function as well as anticancer effect preventing cancer cell metastasis. ...Human liver cancer HepG2 cell were treated with 10, 20, 30 and 40 M xanthohumol for 48
Xanthohumol may prevent and cure diabetes and atherosis, have oxidation resistance and antiviral function as well as anticance
Therapeutic effect of Xanthohumol against highly pathogenic porcine reproductive and respiratory syndrome viruses.
Liu X, Bai J, Jiang C, Song Z, Zhao Y, Nauwynck H, Jiang P. Liu X, et al. Vet Microbiol. 2019 Nov;238:108431. doi: 10.1016/j.vetmic.2019.108431. Epub 2019 Sep 26. Vet Microbiol. 2019. PMID: 31648725
Thus, novel approaches to control PRRSV infection are essential for the robust and sustainable swine industry. In our previous study, Xanthohumol (Xn), a prenylated flavonoid extracted for hops (Humulus lupulus L), was screened from 386 natural products to inhibit PRRSV pr …
Thus, novel approaches to control PRRSV infection are essential for the robust and sustainable swine industry. In our previous study, Xan
Antiviral activity of hop constituents against a series of DNA and RNA viruses.
Buckwold VE, Wilson RJ, Nalca A, Beer BB, Voss TG, Turpin JA, Buckheit RW 3rd, Wei J, Wenzel-Mathers M, Walton EM, Smith RJ, Pallansch M, Ward P, Wells J, Chuvala L, Sloane S, Paulman R, Russell J, Hartman T, Ptak R. Buckwold VE, et al. Antiviral Res. 2004 Jan;61(1):57-62. doi: 10.1016/s0166-3542(03)00155-4. Antiviral Res. 2004. PMID: 14670594
Xanthohumol was found to be a more potent antiviral agent against these viruses than the isomer iso-xanthohumol. With Rhino, the opposite trend was observed with iso-xanthohumol showing superior antiviral activity to that observed with xantho
Xanthohumol was found to be a more potent antiviral agent against these viruses than the isomer iso-xanthohumol. With R
Broad spectrum anti-infective potential of xanthohumol from hop (Humulus lupulus L.) in comparison with activities of other hop constituents and xanthohumol metabolites.
Gerhäuser C. Gerhäuser C. Mol Nutr Food Res. 2005 Sep;49(9):827-31. doi: 10.1002/mnfr.200500091. Mol Nutr Food Res. 2005. PMID: 16092071 Review.
This review summarizes the capacity of xanthohumol (XN) in comparison with additional hop constituents and metabolites to act as an antiinfective agent against microorganisms including bacteria, viruses, fungi and malarial protozoa. XN was shown to inhibit the Gram-positiv …
This review summarizes the capacity of xanthohumol (XN) in comparison with additional hop constituents and metabolites to act as an a …
Xanthohumol enhances antiviral effect of interferon alpha-2b against bovine viral diarrhea virus, a surrogate of hepatitis C virus.
Zhang N, Liu Z, Han Q, Chen J, Lv Y. Zhang N, et al. Phytomedicine. 2010 Apr;17(5):310-6. doi: 10.1016/j.phymed.2009.08.005. Epub 2009 Sep 11. Phytomedicine. 2010. PMID: 19748253
Xanthohumol (XN) is a natural compound with multifunctional potentials, including antiviral activity. In this study, the antiviral activity of addition of XN to interferon (IFN)-alpha was examined and compared with each compound alone using bovine viral diarr
Xanthohumol (XN) is a natural compound with multifunctional potentials, including antiviral activity. In this study, the an
Inhibition of bovine viral diarrhea virus in vitro by xanthohumol: comparisons with ribavirin and interferon-alpha and implications for the development of anti-hepatitis C virus agents.
Zhang N, Liu Z, Han Q, Chen J, Lou S, Qiu J, Zhang G. Zhang N, et al. Eur J Pharm Sci. 2009 Nov 5;38(4):332-40. doi: 10.1016/j.ejps.2009.08.005. Epub 2009 Aug 29. Eur J Pharm Sci. 2009. PMID: 19720145
Xanthohumol (XN) is a natural compound with potential antiviral activity. In this study, the ability of XN to inhibit bovine viral diarrhea virus (BVDV), a surrogate model of hepatitis C virus (HCV), was investigated. The antiviral activity of XN was compared
Xanthohumol (XN) is a natural compound with potential antiviral activity. In this study, the ability of XN to inhibit bovine v
22 results