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Year Number of Results
2004 2
2005 1
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2009 2
2010 2
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2014 1
2015 3
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2017 2
2019 2
2020 1
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Therapeutic effect of Xanthohumol against highly pathogenic porcine reproductive and respiratory syndrome viruses.
Liu X, Bai J, Jiang C, Song Z, Zhao Y, Nauwynck H, Jiang P. Liu X, et al. Vet Microbiol. 2019 Nov;238:108431. doi: 10.1016/j.vetmic.2019.108431. Epub 2019 Sep 26. Vet Microbiol. 2019. PMID: 31648725
In our previous study, Xanthohumol (Xn), a prenylated flavonoid extracted for hops (Humulus lupulus L), was screened from 386 natural products to inhibit PRRSV proliferation and alleviate oxidative stress induced by PRRSV via the Nrf2-HMOX1 axis in Marc-145 cells. ...
In our previous study, Xanthohumol (Xn), a prenylated flavonoid extracted for hops (Humulus lupulus L), was screened from 386 natural …
Anticancer effect of xanthohumol induces growth inhibition and apoptosis of human liver cancer through NF-κB/p53-apoptosis signaling pathway.
Zhao X, Jiang K, Liang B, Huang X. Zhao X, et al. Oncol Rep. 2016 Feb;35(2):669-75. doi: 10.3892/or.2015.4455. Epub 2015 Nov 26. Oncol Rep. 2016. PMID: 26718026 Free PMC article.
Xanthohumol may prevent and cure diabetes and atherosis, have oxidation resistance and antiviral function as well as anticancer effect preventing cancer cell metastasis. ...Human liver cancer HepG2 cell were treated with 10, 20, 30 and 40 µM xanthohumol for 4 …
Xanthohumol may prevent and cure diabetes and atherosis, have oxidation resistance and antiviral function as well as anticance …
Antiviral activity of hop constituents against a series of DNA and RNA viruses.
Buckwold VE, Wilson RJ, Nalca A, Beer BB, Voss TG, Turpin JA, Buckheit RW 3rd, Wei J, Wenzel-Mathers M, Walton EM, Smith RJ, Pallansch M, Ward P, Wells J, Chuvala L, Sloane S, Paulman R, Russell J, Hartman T, Ptak R. Buckwold VE, et al. Antiviral Res. 2004 Jan;61(1):57-62. doi: 10.1016/s0166-3542(03)00155-4. Antiviral Res. 2004. PMID: 14670594
Xanthohumol was found to be a more potent antiviral agent against these viruses than the isomer iso-xanthohumol. With Rhino, the opposite trend was observed with iso-xanthohumol showing superior antiviral activity to that observed with xantho …
Xanthohumol was found to be a more potent antiviral agent against these viruses than the isomer iso-xanthohumol. With R …
Xanthohumol enhances antiviral effect of interferon alpha-2b against bovine viral diarrhea virus, a surrogate of hepatitis C virus.
Zhang N, Liu Z, Han Q, Chen J, Lv Y. Zhang N, et al. Phytomedicine. 2010 Apr;17(5):310-6. doi: 10.1016/j.phymed.2009.08.005. Epub 2009 Sep 11. Phytomedicine. 2010. PMID: 19748253
Xanthohumol (XN) is a natural compound with multifunctional potentials, including antiviral activity. In this study, the antiviral activity of addition of XN to interferon (IFN)-alpha was examined and compared with each compound alone using bovine viral diarr …
Xanthohumol (XN) is a natural compound with multifunctional potentials, including antiviral activity. In this study, the an …
Xanthohumol, a main prenylated chalcone from hops, reduces liver damage and modulates oxidative reaction and apoptosis in hepatitis C virus infected Tupaia belangeri.
Yang M, Li N, Li F, Zhu Q, Liu X, Han Q, Wang Y, Chen Y, Zeng X, Lv Y, Zhang P, Yang C, Liu Z. Yang M, et al. Int Immunopharmacol. 2013 Aug;16(4):466-74. doi: 10.1016/j.intimp.2013.04.029. Epub 2013 May 10. Int Immunopharmacol. 2013. PMID: 23669332
Xanthohumol (XN), a major prenylated chalcone from hops, has various biological activities including hepatopreventive and anti-viral activities. ...
Xanthohumol (XN), a major prenylated chalcone from hops, has various biological activities including hepatopreventive and anti-viral …
Broad spectrum anti-infective potential of xanthohumol from hop (Humulus lupulus L.) in comparison with activities of other hop constituents and xanthohumol metabolites.
Gerhäuser C. Gerhäuser C. Mol Nutr Food Res. 2005 Sep;49(9):827-31. doi: 10.1002/mnfr.200500091. Mol Nutr Food Res. 2005. PMID: 16092071 Review.
This review summarizes the capacity of xanthohumol (XN) in comparison with additional hop constituents and metabolites to act as an antiinfective agent against microorganisms including bacteria, viruses, fungi and malarial protozoa. ...Antiviral activity was demonst …
This review summarizes the capacity of xanthohumol (XN) in comparison with additional hop constituents and metabolites to act as an a …
Inhibition of bovine viral diarrhea virus in vitro by xanthohumol: comparisons with ribavirin and interferon-alpha and implications for the development of anti-hepatitis C virus agents.
Zhang N, Liu Z, Han Q, Chen J, Lou S, Qiu J, Zhang G. Zhang N, et al. Eur J Pharm Sci. 2009 Nov 5;38(4):332-40. doi: 10.1016/j.ejps.2009.08.005. Epub 2009 Aug 29. Eur J Pharm Sci. 2009. PMID: 19720145
Xanthohumol (XN) is a natural compound with potential antiviral activity. In this study, the ability of XN to inhibit bovine viral diarrhea virus (BVDV), a surrogate model of hepatitis C virus (HCV), was investigated. The antiviral activity of XN was compared …
Xanthohumol (XN) is a natural compound with potential antiviral activity. In this study, the ability of XN to inhibit bovine v …
Inhibition of hepatitis C virus replication in vitro by xanthohumol, a natural product present in hops.
Lou S, Zheng YM, Liu SL, Qiu J, Han Q, Li N, Zhu Q, Zhang P, Yang C, Liu Z. Lou S, et al. Planta Med. 2014 Feb;80(2-3):171-6. doi: 10.1055/s-0033-1360172. Epub 2013 Dec 19. Planta Med. 2014. PMID: 24356905
Xanthohumol, a prenylated flavonoid from hops, has various biological activities including an antiviral effect. It was previously characterized as a compound that inhibits bovine viral diarrhea virus, a surrogate model of hepatitis C virus. ...Xanthohumol at …
Xanthohumol, a prenylated flavonoid from hops, has various biological activities including an antiviral effect. It was previou …
Xanthohumol induces apoptosis in human malignant glioblastoma cells by increasing reactive oxygen species and activating MAPK pathways.
Festa M, Capasso A, D'Acunto CW, Masullo M, Rossi AG, Pizza C, Piacente S. Festa M, et al. J Nat Prod. 2011 Dec 27;74(12):2505-13. doi: 10.1021/np200390x. Epub 2011 Nov 23. J Nat Prod. 2011. PMID: 22111577
Xanthohumol induced intracellular reactive oxygen species (ROS), an effect that was reduced by pretreatment with the antioxidant N-acetyl-L-cysteine (NAC). ...These findings suggest that xanthohumol (1) is a potential chemotherapeutic agent for the treatment of glio …
Xanthohumol induced intracellular reactive oxygen species (ROS), an effect that was reduced by pretreatment with the antioxidant N-ac …
Xanthohumol impairs glucose uptake by a human first-trimester extravillous trophoblast cell line (HTR-8/SVneo cells) and impacts the process of placentation.
Correia-Branco A, Azevedo CF, Araújo JR, Guimarães JT, Faria A, Keating E, Martel F. Correia-Branco A, et al. Mol Hum Reprod. 2015 Oct;21(10):803-15. doi: 10.1093/molehr/gav043. Epub 2015 Jul 20. Mol Hum Reprod. 2015. PMID: 26194608
In the short term (30 min), neither 5-HT (100-1000 µM), melatonin (10 nM) nor the drugs of abuse ethanol (100 mM), nicotine (100 µM), cocaine (25 µM), amphetamine (10-25 µM) and 3,4-methylenedioxy-N-methamphetamine (10 µM) affected (3)H-DG uptake, while dexamethasone (100-1000 µM …
In the short term (30 min), neither 5-HT (100-1000 µM), melatonin (10 nM) nor the drugs of abuse ethanol (100 mM), nicotine (100 µM), cocain …
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