Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My Custom Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2004 2
2005 1
2008 2
2009 2
2010 2
2011 1
2013 3
2014 1
2015 3
2016 1
2017 2
2019 2
2020 1
2021 3
2022 3
2023 3
2024 1
2025 1

Publication date

Text availability

Article attribute

Article type

Additional filters

Article Language

Species

Sex

Age

Other

Search Results

28 results

Results by year

Filters applied: . Clear all
Page 1
Xanthohumol for Human Malignancies: Chemistry, Pharmacokinetics and Molecular Targets.
Harish V, Haque E, Śmiech M, Taniguchi H, Jamieson S, Tewari D, Bishayee A. Harish V, et al. Int J Mol Sci. 2021 Apr 25;22(9):4478. doi: 10.3390/ijms22094478. Int J Mol Sci. 2021. PMID: 33923053 Free PMC article. Review.
Xanthohumol (XH) is an important prenylated flavonoid that is found within the inflorescence of Humulus lupulus L. ...XH is an important ingredient in beer and is considered a significant bioactive agent due to its diverse medicinal applications, which include anti-inflamm …
Xanthohumol (XH) is an important prenylated flavonoid that is found within the inflorescence of Humulus lupulus L. ...XH is an import …
Xanthohumol: An underestimated, while potent and promising chemotherapeutic agent in cancer treatment.
Vesaghhamedani S, Ebrahimzadeh F, Najafi E, Shabgah OG, Askari E, Shabgah AG, Mohammadi H, Jadidi-Niaragh F, Navashenaq JG. Vesaghhamedani S, et al. Prog Biophys Mol Biol. 2022 Aug;172:3-14. doi: 10.1016/j.pbiomolbio.2022.04.002. Epub 2022 Apr 8. Prog Biophys Mol Biol. 2022. PMID: 35405185 Review.
Today, there is a growing interest nowadays in the use of herbal substances as cancer therapeutic agents. Over recent years, Xanthohumol (XTL) has been brought out as a prenylated chalcone that is found in hops (Humulus lupulus) and beer. ...Additionally, XTL deriva …
Today, there is a growing interest nowadays in the use of herbal substances as cancer therapeutic agents. Over recent years, Xanth …
Xanthohumol prolongs lifespan and decreases stress-induced mortality in Drosophila melanogaster.
Wongchum N, Dechakhamphu A. Wongchum N, et al. Comp Biochem Physiol C Toxicol Pharmacol. 2021 Jun;244:108994. doi: 10.1016/j.cbpc.2021.108994. Epub 2021 Feb 4. Comp Biochem Physiol C Toxicol Pharmacol. 2021. PMID: 33549830
Drosophila or fruit fly is one of the most effective models for the evaluation of anti-aging compounds. Xanthohumol (XN) is a potential bioactive substance for the prevention and treatment of many diseases. The previous studies have reported its potent activities as antiox …
Drosophila or fruit fly is one of the most effective models for the evaluation of anti-aging compounds. Xanthohumol (XN) is a potenti …
Antiviral Activity and Molecular Dynamics Simulation of Hops Compounds against Oropouche Virus (Peribunyaviridae).
Mandova T, Saivish MV, Menezes GL, Bezerra KS, Fulco UL, da Silva RA, Da Costa FB, Nogueira ML. Mandova T, et al. Pharmaceutics. 2023 Dec 13;15(12):2769. doi: 10.3390/pharmaceutics15122769. Pharmaceutics. 2023. PMID: 38140109 Free PMC article.
In this study, we aimed to explore acylphloroglucinols and xanthohumol from hops (Humulus lupulus L.) as a promising alternative for antiviral therapies. ...In conclusion, the beta acids showed strongest inhibitory potential in post-treatment assay (EC(50) = 26.7 g/ …
In this study, we aimed to explore acylphloroglucinols and xanthohumol from hops (Humulus lupulus L.) as a promising alternative for …
Anticancer effect of xanthohumol induces growth inhibition and apoptosis of human liver cancer through NF-kappaB/p53-apoptosis signaling pathway.
Zhao X, Jiang K, Liang B, Huang X. Zhao X, et al. Oncol Rep. 2016 Feb;35(2):669-75. doi: 10.3892/or.2015.4455. Epub 2015 Nov 26. Oncol Rep. 2016. PMID: 26718026 Free PMC article.
Xanthohumol may prevent and cure diabetes and atherosis, have oxidation resistance and antiviral function as well as anticancer effect preventing cancer cell metastasis. ...Human liver cancer HepG2 cell were treated with 10, 20, 30 and 40 M xanthohumol for 48 …
Xanthohumol may prevent and cure diabetes and atherosis, have oxidation resistance and antiviral function as well as anticance …
The Role of Diet and Supplements in the Prevention and Progression of COVID-19: Current Knowledge and Open Issues.
Rossi RE, Chen J, Caplin ME. Rossi RE, et al. Prev Nutr Food Sci. 2022 Jun 30;27(2):137-149. doi: 10.3746/pnf.2022.27.2.137. Prev Nutr Food Sci. 2022. PMID: 35919576 Free PMC article. Review.
Animal studies have investigated the effects of green tea and curcumin. Xanthohumol and probiotics, interesting for their antiviral, anti-inflammatory, and immunoregulatory properties, need formal clinical study. ...
Animal studies have investigated the effects of green tea and curcumin. Xanthohumol and probiotics, interesting for their antivira …
Broad spectrum anti-infective potential of xanthohumol from hop (Humulus lupulus L.) in comparison with activities of other hop constituents and xanthohumol metabolites.
Gerhäuser C. Gerhäuser C. Mol Nutr Food Res. 2005 Sep;49(9):827-31. doi: 10.1002/mnfr.200500091. Mol Nutr Food Res. 2005. PMID: 16092071 Review.
This review summarizes the capacity of xanthohumol (XN) in comparison with additional hop constituents and metabolites to act as an antiinfective agent against microorganisms including bacteria, viruses, fungi and malarial protozoa. XN was shown to inhibit the Gram-positiv …
This review summarizes the capacity of xanthohumol (XN) in comparison with additional hop constituents and metabolites to act as an a …
Antiviral activity of hop constituents against a series of DNA and RNA viruses.
Buckwold VE, Wilson RJ, Nalca A, Beer BB, Voss TG, Turpin JA, Buckheit RW 3rd, Wei J, Wenzel-Mathers M, Walton EM, Smith RJ, Pallansch M, Ward P, Wells J, Chuvala L, Sloane S, Paulman R, Russell J, Hartman T, Ptak R. Buckwold VE, et al. Antiviral Res. 2004 Jan;61(1):57-62. doi: 10.1016/s0166-3542(03)00155-4. Antiviral Res. 2004. PMID: 14670594
Xanthohumol was found to be a more potent antiviral agent against these viruses than the isomer iso-xanthohumol. ...These hop constituents might serve as interesting lead compounds from which more active anti-HCV, anti-Rhino and anti-herpesvirus antiviral …
Xanthohumol was found to be a more potent antiviral agent against these viruses than the isomer iso-xanthohumol. ...The …
Modulation of the replication of positive-sense RNA viruses by the natural plant metabolite xanthohumol and its derivatives.
Marongiu L, Burkard M, Helling T, Biendl M, Venturelli S. Marongiu L, et al. Crit Rev Food Sci Nutr. 2025;65(3):429-443. doi: 10.1080/10408398.2023.2275169. Epub 2023 Nov 9. Crit Rev Food Sci Nutr. 2025. PMID: 37942943 Review.
The COVID-19 pandemic has highlighted the importance of identifying new potent antiviral agents. Nutrients as well as plant-derived substances are promising candidates because they are usually well tolerated by the human body and readily available in nature, and con …
The COVID-19 pandemic has highlighted the importance of identifying new potent antiviral agents. Nutrients as well as plant-de …
Isoxanthohumol--Biologically active hop flavonoid.
Żołnierczyk AK, Mączka WK, Grabarczyk M, Wińska K, Woźniak E, Anioł M. Żołnierczyk AK, et al. Fitoterapia. 2015 Jun;103:71-82. doi: 10.1016/j.fitote.2015.03.007. Epub 2015 Mar 12. Fitoterapia. 2015. PMID: 25771121
Isoxanthohumol (IXN), apart from xanthohumol (XN) and 8-prenylnaringenin (8PN), is one of the most important prenylflavonoids found in hops. ...It activates apoptosis in human umbilical vein endothelial cells (HUVEC) and human aortic smooth muscle cells (HASMCs). In additi …
Isoxanthohumol (IXN), apart from xanthohumol (XN) and 8-prenylnaringenin (8PN), is one of the most important prenylflavonoids found i …
28 results