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Prostate and breast cancer cells death induced by xanthohumol investigated with Fourier transform infrared spectroscopy.
Gieroba B, Arczewska M, Sławińska-Brych A, Rzeski W, Stepulak A, Gagoś M. Gieroba B, et al. Spectrochim Acta A Mol Biomol Spectrosc. 2020 Apr 15;231:118112. doi: 10.1016/j.saa.2020.118112. Epub 2020 Jan 25. Spectrochim Acta A Mol Biomol Spectrosc. 2020. PMID: 32014658 Free article.
Fourier Transform Infrared spectroscopy was applied to detect in vitro cell death induced in prostate (PC-3) and breast (T47D) cancer cell lines treated with xanthohumol (XN). After incubation of the cancer cells with XN, specific spectral shifts in the infrared spe …
Fourier Transform Infrared spectroscopy was applied to detect in vitro cell death induced in prostate (PC-3) and breast (T47D) cancer …
2-Hydroxychalcone and xanthohumol inhibit invasion of triple negative breast cancer cells.
Kim SY, Lee IS, Moon A. Kim SY, et al. Chem Biol Interact. 2013 May 25;203(3):565-72. doi: 10.1016/j.cbi.2013.03.012. Epub 2013 Apr 3. Chem Biol Interact. 2013. PMID: 23562496
Breast cancer is estimated as one of the most common causes of cancer death among women. ...Similarly, Chalcone, 2-hydroxychalcone, and xanthohumol also exerted cytotoxicity in another TNBC cell line, Hs578T. ...
Breast cancer is estimated as one of the most common causes of cancer death among women. ...Similarly, Chalcone, 2-hydroxychalcone, a …
Controlled release of resveratrol and xanthohumol via coaxial electrospinning fibers.
Zhang X, Han L, Sun Q, Xia W, Zhou Q, Zhang Z, Song X. Zhang X, et al. J Biomater Sci Polym Ed. 2020 Mar;31(4):456-471. doi: 10.1080/09205063.2019.1700600. Epub 2019 Dec 17. J Biomater Sci Polym Ed. 2020. PMID: 31801405
Synergistic delivery of two drugs is a desirable choice to overcome drug resistance. Resveratrol (RES) and xanthohumol (XAN) which are both new drugs originated from plants exhibit great potential in the treatment of cancer, but there are few studies on combining them in a …
Synergistic delivery of two drugs is a desirable choice to overcome drug resistance. Resveratrol (RES) and xanthohumol (XAN) which ar …
Inhibition of breast cancer cell survival by Xanthohumol via modulation of the Notch signaling pathway in vivo and in vitro.
Sun Z, Zhou C, Liu F, Zhang W, Chen J, Pan Y, Ma L, Liu Q, Du Y, Yang J, Wang Q. Sun Z, et al. Oncol Lett. 2018 Jan;15(1):908-916. doi: 10.3892/ol.2017.7434. Epub 2017 Nov 17. Oncol Lett. 2018. PMID: 29422966 Free PMC article.
The purpose of the present study was to clarify the antitumorigenic effects and the underlying mechanism of XN on breast cancer in vivo and in vitro. A 4T1 breast tumor mouse model was used in the present study to investigate XN suppression of tumor growth as detect …
The purpose of the present study was to clarify the antitumorigenic effects and the underlying mechanism of XN on breast cancer in vi …
The influence of a single and double biotinylation of xanthohumol on its anticancer activity.
Stompor M, Świtalska M, Wietrzyk J. Stompor M, et al. Acta Biochim Pol. 2019 Dec 10;66(4):559-565. doi: 10.18388/abp.2019_2876. Acta Biochim Pol. 2019. PMID: 31820895 Free article.

For all three tested compounds the best activity was noted in the case of human (MCF-7) and mice (4T1) breast cancer cell lines (IC50 values < 9 muM). Both biotinylated derivatives showed slightly higher anticancer activity than xanthohumol (1) towards all types

…
For all three tested compounds the best activity was noted in the case of human (MCF-7) and mice (4T1) breast cancer cell lines (IC50 …
Effect of xanthohumol and 8-prenylnaringenin on MCF-7 breast cancer cells oxidative stress and mitochondrial complexes expression.
Blanquer-Rosselló MM, Oliver J, Valle A, Roca P. Blanquer-Rosselló MM, et al. J Cell Biochem. 2013 Dec;114(12):2785-94. doi: 10.1002/jcb.24627. J Cell Biochem. 2013. PMID: 23836544
Xanthohumol (XN) and 8-prenylnaringenin (8PN) are hop (Humulus lupulus L.) polyphenols studied for their chemopreventive effects on certain cancer types. The breast cancer line MCF-7 was treated with doses ranging from 0.001 to 20 M of XN or 8PN in order to assess t …
Xanthohumol (XN) and 8-prenylnaringenin (8PN) are hop (Humulus lupulus L.) polyphenols studied for their chemopreventive effects on c …
PEG-GO@XN nanocomposite suppresses breast cancer metastasis via inhibition of mitochondrial oxidative phosphorylation and blockade of epithelial-to-mesenchymal transition.
Zhang J, Yan L, Wei P, Zhou R, Hua C, Xiao M, Tu Y, Gu Z, Wei T. Zhang J, et al. Eur J Pharmacol. 2021 Mar 15;895:173866. doi: 10.1016/j.ejphar.2021.173866. Epub 2021 Jan 14. Eur J Pharmacol. 2021. PMID: 33454376
Metastatic breast cancer is a significant contributor to mortality among women, but its complex regulation represents a barrier to precision targeting. ...PEG-GO@XN is capable of inhibiting mitochondrial oxidative phosphorylation selectively in MDA-MB-231 and MDA-MB-436 me …
Metastatic breast cancer is a significant contributor to mortality among women, but its complex regulation represents a barrier to pr …
Distinct modulation of alkaline phosphatase isoenzymes by 17beta-estradiol and xanthohumol in breast cancer MCF-7 cells.
Guerreiro S, Monteiro R, Martins MJ, Calhau C, Azevedo I, Soares R. Guerreiro S, et al. Clin Biochem. 2007 Feb;40(3-4):268-73. doi: 10.1016/j.clinbiochem.2006.09.012. Epub 2006 Oct 19. Clin Biochem. 2007. PMID: 17126313
OBJECTIVES: To examine the effect of 17beta-estradiol and xanthohumol in alkaline phosphatase (ALP) expression and activity in breast cancer MCF-7 cells. ...ALP loss associated with increased cell proliferation. Modulation of this enzyme by 17beta-estradiol and x …
OBJECTIVES: To examine the effect of 17beta-estradiol and xanthohumol in alkaline phosphatase (ALP) expression and activity in bre …
Xanthohumol inhibits inflammatory factor production and angiogenesis in breast cancer xenografts.
Monteiro R, Calhau C, Silva AO, Pinheiro-Silva S, Guerreiro S, Gärtner F, Azevedo I, Soares R. Monteiro R, et al. J Cell Biochem. 2008 Aug 1;104(5):1699-707. doi: 10.1002/jcb.21738. J Cell Biochem. 2008. PMID: 18348194
Xanthohumol (XN), a natural polyphenol present in beer, is known to exert anti-cancer effects. ...These novel findings indicate that XN is able to target both breast cancer and host cells, namely inflammatory and endothelial cells, suggesting its potential use as a …
Xanthohumol (XN), a natural polyphenol present in beer, is known to exert anti-cancer effects. ...These novel findings indicate that …
Xanthohumol, a Prenylated Chalcone from Hops, Inhibits the Viability and Stemness of Doxorubicin-Resistant MCF-7/ADR Cells.
Liu M, Yin H, Qian X, Dong J, Qian Z, Miao J. Liu M, et al. Molecules. 2016 Dec 28;22(1):36. doi: 10.3390/molecules22010036. Molecules. 2016. PMID: 28036030 Free PMC article.
Xanthohumol is a unique prenylated flavonoid in hops (Humulus lupulus L.) and beer. ...These results demonstrate that xanthohumol is a promising compound targeting the doxorubicin resistant breast cancer cells and regulating their stemness, which, therefore, …
Xanthohumol is a unique prenylated flavonoid in hops (Humulus lupulus L.) and beer. ...These results demonstrate that xanthohumol …
42 results