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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2002 1
2004 1
2005 7
2006 2
2007 7
2008 3
2009 1
2010 1
2011 1
2012 6
2013 2
2014 3
2015 1
2016 6
2017 2
2018 4
2019 6
2020 2
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49 results
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The Cancer Prevention, Anti-Inflammatory and Anti-Oxidation of Bioactive Phytochemicals Targeting the TLR4 Signaling Pathway.
Chen CY, Kao CL, Liu CM. Chen CY, et al. Int J Mol Sci. 2018 Sep 12;19(9):2729. doi: 10.3390/ijms19092729. Int J Mol Sci. 2018. PMID: 30213077 Free PMC article. Review.
Recently, an increasing number studies have shown the link between TLRs and cancer. Among them, the toll-like receptor 4 (TLR4) signaling pathway is associated with inflammatory response and cancer progression. ...Curcumin, 6-gingerol, 6-shogaol, 1-dehydro-10-ginger …
Recently, an increasing number studies have shown the link between TLRs and cancer. Among them, the toll-like receptor 4 (TLR4) signa …
Inflammation, a Double-Edge Sword for Cancer and Other Age-Related Diseases.
Gupta SC, Kunnumakkara AB, Aggarwal S, Aggarwal BB. Gupta SC, et al. Front Immunol. 2018 Sep 27;9:2160. doi: 10.3389/fimmu.2018.02160. eCollection 2018. Front Immunol. 2018. PMID: 30319623 Free PMC article. Review.
Increasing evidence from diverse sources during the past several years has indicated that long-term, low level, chronic inflammation mediates several chronic diseases including cancer, arthritis, obesity, diabetes, cardiovascular diseases, and neurological diseases. ...Thu …
Increasing evidence from diverse sources during the past several years has indicated that long-term, low level, chronic inflammation mediate …
Prenylated chalcones and flavonoids for the prevention and treatment of cancer.
Venturelli S, Burkard M, Biendl M, Lauer UM, Frank J, Busch C. Venturelli S, et al. Nutrition. 2016 Nov-Dec;32(11-12):1171-8. doi: 10.1016/j.nut.2016.03.020. Epub 2016 Apr 8. Nutrition. 2016. PMID: 27238957 Review.
Prenylated chalcones and flavonoids gained increasing attention not only in nutrition but also in cancer prevention because of their biological and molecular activities in humans, which have been extensively investigated in vitro or in preclinical studies. ...This r …
Prenylated chalcones and flavonoids gained increasing attention not only in nutrition but also in cancer prevention because of …
Xanthohumol inhibits colorectal cancer cells via downregulation of Hexokinases II-mediated glycolysis.
Liu W, Li W, Liu H, Yu X. Liu W, et al. Int J Biol Sci. 2019 Sep 7;15(11):2497-2508. doi: 10.7150/ijbs.37481. eCollection 2019. Int J Biol Sci. 2019. PMID: 31595166 Free PMC article.
Xanthohumol suppressed CRC cell growth both in vitro and in vivo. Treatment with xanthohumol promoted the release of cytochrome C and activated the intrinsic apoptosis pathway. ...Our results suggest that targeting HK2 appears to be a new approach for clinical CRC
Xanthohumol suppressed CRC cell growth both in vitro and in vivo. Treatment with xanthohumol promoted the release of cytochrom
Nutraceuticals and "Repurposed" Drugs of Phytochemical Origin in Prevention and Interception of Chronic Degenerative Diseases and Cancer.
Albini A, Bassani B, Baci D, Dallaglio K, Gallazzi M, Corradino P, Bruno A, Noonan DM. Albini A, et al. Curr Med Chem. 2019;26(6):973-987. doi: 10.2174/0929867324666170920144130. Curr Med Chem. 2019. PMID: 28933290 Review.
For these pathologies, including rheumatoid arthritis, cardiovascular and autoimmune diseases, cancer, diabetes, and obesity, current therapies have limited efficacy. OBJECTIVES: The validation of novel (chemo)preventive and interceptive approaches, and the use of n …
For these pathologies, including rheumatoid arthritis, cardiovascular and autoimmune diseases, cancer, diabetes, and obesity, current …
Xanthohumol exhibits anti-myeloma activity in vitro through inhibition of cell proliferation, induction of apoptosis via the ERK and JNK-dependent mechanism, and suppression of sIL-6R and VEGF production.
Sławińska-Brych A, Zdzisińska B, Czerwonka A, Mizerska-Kowalska M, Dmoszyńska-Graniczka M, Stepulak A, Gagoś M. Sławińska-Brych A, et al. Biochim Biophys Acta Gen Subj. 2019 Nov;1863(11):129408. doi: 10.1016/j.bbagen.2019.08.001. Epub 2019 Aug 3. Biochim Biophys Acta Gen Subj. 2019. PMID: 31386885
BACKGROUND: Xanthohumol (XN, a hop-derived prenylflavonoid) was found to exert anticancer effects on various cancer types. However, the mechanisms by which XN affects the survival of multiple myeloma cells (MM) are little known. ...The apoptotic process was probably …
BACKGROUND: Xanthohumol (XN, a hop-derived prenylflavonoid) was found to exert anticancer effects on various cancer types. How …
Anticancer effect of xanthohumol induces growth inhibition and apoptosis of human liver cancer through NF-κB/p53-apoptosis signaling pathway.
Zhao X, Jiang K, Liang B, Huang X. Zhao X, et al. Oncol Rep. 2016 Feb;35(2):669-75. doi: 10.3892/or.2015.4455. Epub 2015 Nov 26. Oncol Rep. 2016. PMID: 26718026 Free PMC article.
Xanthohumol may prevent and cure diabetes and atherosis, have oxidation resistance and antiviral function as well as anticancer effect preventing cancer cell metastasis. ...Human liver cancer HepG2 cell were treated with 10, 20, 30 and 40 µM
Xanthohumol may prevent and cure diabetes and atherosis, have oxidation resistance and antiviral function as well as anticance
Targeting oncogenic transcription factors by polyphenols: A novel approach for cancer therapy.
Rajagopal C, Lankadasari MB, Aranjani JM, Harikumar KB. Rajagopal C, et al. Pharmacol Res. 2018 Apr;130:273-291. doi: 10.1016/j.phrs.2017.12.034. Epub 2018 Jan 4. Pharmacol Res. 2018. PMID: 29305909 Review.
Inflammation is one of the major causative factor of cancer and chronic inflammation is involved in all the major steps of cancer initiation, progression metastasis and drug resistance. ...Further combination of these natural products along with currently approved …
Inflammation is one of the major causative factor of cancer and chronic inflammation is involved in all the major steps of cancer
Xanthohumol and related prenylflavonoids from hops and beer: to your good health!
Stevens JF, Page JE. Stevens JF, et al. Phytochemistry. 2004 May;65(10):1317-30. doi: 10.1016/j.phytochem.2004.04.025. Phytochemistry. 2004. PMID: 15231405 Review.
Xanthohumol has been characterized a 'broad-spectrum' cancer chemopreventive agent in in vitro studies, while 8-prenylnaringenin enjoys fame as the most potent phytoestrogen known to date. These biological activities suggest that prenylflavonoids from hops have pote
Xanthohumol has been characterized a 'broad-spectrum' cancer chemopreventive agent in in vitro studies, while 8-prenylnaringen
Angiogenesis and cancer prevention: a vision.
Noonan DM, Benelli R, Albini A. Noonan DM, et al. Recent Results Cancer Res. 2007;174:219-24. doi: 10.1007/978-3-540-37696-5_19. Recent Results Cancer Res. 2007. PMID: 17302199 Review.
N-acetyl-cysteine, and the green tea flavonoid epigallocatechin-3-gallate (EGCG) and the beer/ hops-derived chalcone Xanthohumol all prevent angiogenesis in the Matrigel sponge angiogenic assay in vivo and inhibit the growth of the highly angiogenic Kaposi's
N-acetyl-cysteine, and the green tea flavonoid epigallocatechin-3-gallate (EGCG) and the beer/ hops-derived chalcone Xanthohumol all …
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