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69 results

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Page 1
Xanthohumol from Hop: Hope for cancer prevention and treatment.
Girisa S, Saikia Q, Bordoloi D, Banik K, Monisha J, Daimary UD, Verma E, Ahn KS, Kunnumakkara AB. Girisa S, et al. IUBMB Life. 2021 Aug;73(8):1016-1044. doi: 10.1002/iub.2522. Epub 2021 Jul 6. IUBMB Life. 2021. PMID: 34170599 Free article. Review.
The factors such as drug resistance, lack of specificity, and low efficacy of the cancer drugs necessitate developing alternative strategies for the prevention and treatment of this disease. Xanthohumol (XN), a prenylated chalcone present in Hop (Humulus lupu …
The factors such as drug resistance, lack of specificity, and low efficacy of the cancer drugs necessitate developing alternative str …
Prenylated chalcones and flavonoids for the prevention and treatment of cancer.
Venturelli S, Burkard M, Biendl M, Lauer UM, Frank J, Busch C. Venturelli S, et al. Nutrition. 2016 Nov-Dec;32(11-12):1171-8. doi: 10.1016/j.nut.2016.03.020. Epub 2016 Apr 8. Nutrition. 2016. PMID: 27238957 Review.
Prenylated chalcones and flavonoids gained increasing attention not only in nutrition but also in cancer prevention because of their biological and molecular activities in humans, which have been extensively investigated in vitro or in preclinical studies. ...This r …
Prenylated chalcones and flavonoids gained increasing attention not only in nutrition but also in cancer prevention because of …
Antitumor Effect and Gut Microbiota Modulation by Quercetin, Luteolin, and Xanthohumol in a Rat Model for Colorectal Cancer Prevention.
Pérez-Valero Á, Magadán-Corpas P, Ye S, Serna-Diestro J, Sordon S, Huszcza E, Popłoński J, Villar CJ, Lombó F. Pérez-Valero Á, et al. Nutrients. 2024 Apr 13;16(8):1161. doi: 10.3390/nu16081161. Nutrients. 2024. PMID: 38674851 Free PMC article.
In this study, we have tested the flavonoids quercetin, luteolin, and xanthohumol as potential antitumor agents in an animal model of colorectal cancer induced by azoxymethane and dodecyl sodium sulphate. Forty rats were divided into four cohorts: Cohort 1 (contr …
In this study, we have tested the flavonoids quercetin, luteolin, and xanthohumol as potential antitumor agents in an animal model of …
The Past and Future of Angiogenesis as a Target for Cancer Therapy and Prevention.
Albini A, Noonan DM, Corradino P, Magnoni F, Corso G. Albini A, et al. Cancer Prev Res (Phila). 2024 Jul 2;17(7):289-303. doi: 10.1158/1940-6207.CAPR-24-0085. Cancer Prev Res (Phila). 2024. PMID: 38714356 Review.
Cancer growth is dependent on angiogenesis, the formation of new blood vessels, which represents a hallmark of cancer. ...However, antiangiogenic therapies are often administered when cancer has already progressed. The key to reducing the cancer burden …
Cancer growth is dependent on angiogenesis, the formation of new blood vessels, which represents a hallmark of cancer. ...Howe …
The Cancer Prevention, Anti-Inflammatory and Anti-Oxidation of Bioactive Phytochemicals Targeting the TLR4 Signaling Pathway.
Chen CY, Kao CL, Liu CM. Chen CY, et al. Int J Mol Sci. 2018 Sep 12;19(9):2729. doi: 10.3390/ijms19092729. Int J Mol Sci. 2018. PMID: 30213077 Free PMC article. Review.
Recently, an increasing number studies have shown the link between TLRs and cancer. Among them, the toll-like receptor 4 (TLR4) signaling pathway is associated with inflammatory response and cancer progression. Dietary phytochemicals are potential modulators of immu …
Recently, an increasing number studies have shown the link between TLRs and cancer. Among them, the toll-like receptor 4 (TLR4) signa …
Bioavailability and Cardiometabolic Effects of Xanthohumol: Evidence from Animal and Human Studies.
Neumann HF, Frank J, Venturelli S, Egert S. Neumann HF, et al. Mol Nutr Food Res. 2022 Mar;66(6):e2100831. doi: 10.1002/mnfr.202100831. Epub 2022 Jan 14. Mol Nutr Food Res. 2022. PMID: 34967501 Review.
Xanthohumol is the main prenylflavonoid in hops and has been associated with a wide range of health benefits, due to its anti-inflammatory, anti-oxidative, and cancer-preventive properties. ...In addition, it provides insights into the pharmacokinetics of …
Xanthohumol is the main prenylflavonoid in hops and has been associated with a wide range of health benefits, due to its anti-inflamm …
Angiogenesis and cancer prevention: a vision.
Noonan DM, Benelli R, Albini A. Noonan DM, et al. Recent Results Cancer Res. 2007;174:219-24. doi: 10.1007/978-3-540-37696-5_19. Recent Results Cancer Res. 2007. PMID: 17302199 Review.
N-acetyl-cysteine, and the green tea flavonoid epigallocatechin-3-gallate (EGCG) and the beer/ hops-derived chalcone Xanthohumol all prevent angiogenesis in the Matrigel sponge angiogenic assay in vivo and inhibit the growth of the highly angiogenic Kaposi's sarcoma …
N-acetyl-cysteine, and the green tea flavonoid epigallocatechin-3-gallate (EGCG) and the beer/ hops-derived chalcone Xanthohumol all …
Xanthohumol for Human Malignancies: Chemistry, Pharmacokinetics and Molecular Targets.
Harish V, Haque E, Śmiech M, Taniguchi H, Jamieson S, Tewari D, Bishayee A. Harish V, et al. Int J Mol Sci. 2021 Apr 25;22(9):4478. doi: 10.3390/ijms22094478. Int J Mol Sci. 2021. PMID: 33923053 Free PMC article. Review.
Xanthohumol (XH) is an important prenylated flavonoid that is found within the inflorescence of Humulus lupulus L. ...Lastly, we focus on its prominent effects and mechanisms of action on various cancers and its possible use in cancer prevention and tr …
Xanthohumol (XH) is an important prenylated flavonoid that is found within the inflorescence of Humulus lupulus L. ...Lastly, we focu …
Inflammation, a Double-Edge Sword for Cancer and Other Age-Related Diseases.
Gupta SC, Kunnumakkara AB, Aggarwal S, Aggarwal BB. Gupta SC, et al. Front Immunol. 2018 Sep 27;9:2160. doi: 10.3389/fimmu.2018.02160. eCollection 2018. Front Immunol. 2018. PMID: 30319623 Free PMC article. Review.
Increasing evidence from diverse sources during the past several years has indicated that long-term, low level, chronic inflammation mediates several chronic diseases including cancer, arthritis, obesity, diabetes, cardiovascular diseases, and neurological diseases. ...The …
Increasing evidence from diverse sources during the past several years has indicated that long-term, low level, chronic inflammation mediate …
Antioxidant Potential of Xanthohumol in Disease Prevention: Evidence from Human and Animal Studies.
Piekara J, Piasecka-Kwiatkowska D. Piekara J, et al. Antioxidants (Basel). 2024 Dec 19;13(12):1559. doi: 10.3390/antiox13121559. Antioxidants (Basel). 2024. PMID: 39765887 Free PMC article. Review.
XN is known as a potent antioxidant compound, which, according to current research, has the potential to prevent and inhibit the development of diseases, i.e., cancer and neurodegenerative diseases. The review aims to examine the antioxidant role of XN in disease …
XN is known as a potent antioxidant compound, which, according to current research, has the potential to prevent and inhibit the deve …
69 results