Xanthohumol Suppresses NPC1L1 Gene Expression through Downregulation of HNF-4α and Inhibits Cholesterol Uptake in Caco-2 Cells.
J Agric Food Chem. 2019 Oct 9;67(40):11119-11128. doi: 10.1021/acs.jafc.9b05221. Epub 2019 Sep 26.
J Agric Food Chem. 2019.
PMID: 31525874
Xanthohumol (Xan) is a prenylated chalcone mainly found in hops; it has been demonstrated to function against hypercholesterolemia, hyperlipidemia, and atherosclerosis. ...These findings reveal that Xan suppresses NPC1L1 expression via downregulation of HNF-4alpha and exer …
Xanthohumol (Xan) is a prenylated chalcone mainly found in hops; it has been demonstrated to function against hypercholesterolemia, h …