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Year Number of Results
1997 1
2000 1
2001 3
2005 5
2006 1
2007 2
2008 1
2009 2
2010 7
2011 3
2012 6
2013 8
2014 6
2015 9
2016 4
2017 8
2018 7
2019 8
2020 7
2021 5
2022 0
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79 results
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Xanthohumol alleviates T2DM-induced liver steatosis and fibrosis by mediating the NRF2/RAGE/NF-κB signaling pathway.
Wang W, Chen Z, Zheng T, Zhang M. Wang W, et al. Future Med Chem. 2021 Dec;13(23):2069-2081. doi: 10.4155/fmc-2021-0241. Epub 2021 Sep 23. Future Med Chem. 2021. PMID: 34551612
Hyperglycemia-associated advanced glycation end products (AGEs) and the receptor for AGE (RAGE) contribute to nonalcoholic fatty liver disease (NAFLD). Xanthohumol (XH) exhibits protective activities against liver diseases. Aim: To investigate the effects of …
Hyperglycemia-associated advanced glycation end products (AGEs) and the receptor for AGE (RAGE) contribute to nonalcoholic fatty liver
Xanthohumol ameliorates Diet-Induced Liver Dysfunction via Farnesoid X Receptor-Dependent and Independent Signaling.
Paraiso IL, Tran TQ, Magana AA, Kundu P, Choi J, Maier CS, Bobe G, Raber J, Kioussi C, Stevens JF. Paraiso IL, et al. Front Pharmacol. 2021 Apr 20;12:643857. doi: 10.3389/fphar.2021.643857. eCollection 2021. Front Pharmacol. 2021. PMID: 33959012 Free PMC article.
Hepatic FXR loss results in lipid and BA accumulation, and progression from hepatic steatosis to nonalcoholic steatohepatitis (NASH). This study aimed to evaluate the effects of xanthohumol (XN), a hop-derived compound mitigating metabolic syndrome, on liver damage …
Hepatic FXR loss results in lipid and BA accumulation, and progression from hepatic steatosis to nonalcoholic steatohepatitis (NASH). This s …
Xanthohumol from Humulus lupulus L. potentiates the killing of Mycobacterium tuberculosis and mitigates liver toxicity by the combination of isoniazid in mouse tuberculosis models.
Lou H, Zhang F, Lu L, Ding Y, Hao X. Lou H, et al. RSC Adv. 2020 Apr 1;10(22):13223-13231. doi: 10.1039/c9ra10347c. eCollection 2020 Mar 30. RSC Adv. 2020. PMID: 35492081 Free PMC article.
The liver damage was induced by treatment with isoniazid daily for 8 weeks. ...Furthermore, other positive outcomes implied that isoniazid combined with xanthohumol obviously alleviated anti-tuberculosis drug induced liver damage as indicated by the declined …
The liver damage was induced by treatment with isoniazid daily for 8 weeks. ...Furthermore, other positive outcomes implied that ison …
Xanthohumol Effect on 2,3,7,8-Tetrachlorodibenzo-p-dioxin-Treated Japanese Quails in Terms of Serum Lipids, Liver Enzymes, Estradiol, and Thyroid Hormones.
Leśków A, Tarnowska MG, Rosińczuk J, Dobrzyński M, Kaliszewski K, Majda J, Żybura-Wszol A K, Sobolewska S, Diakowska D. Leśków A, et al. ACS Omega. 2020 Sep 18;5(38):24445-24452. doi: 10.1021/acsomega.0c02896. eCollection 2020 Sep 29. ACS Omega. 2020. PMID: 33015460 Free PMC article.
The aim of the study was to compare the effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin and XN on lipid, liver enzyme, estradiol, and thyroid enzyme levels in the serum of Japanese quails. ...In comparison with the control group, 2,3,7,8-tetrachlorodibenzo-p-dioxin signific …
The aim of the study was to compare the effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin and XN on lipid, liver enzyme, estradiol, and …
Xanthohumol and 8-prenylnaringenin ameliorate diabetic-related metabolic dysfunctions in mice.
Costa R, Rodrigues I, Guardão L, Rocha-Rodrigues S, Silva C, Magalhães J, Ferreira-de-Almeida M, Negrão R, Soares R. Costa R, et al. J Nutr Biochem. 2017 Jul;45:39-47. doi: 10.1016/j.jnutbio.2017.03.006. Epub 2017 Apr 6. J Nutr Biochem. 2017. PMID: 28431322
Type 2 diabetes mellitus (T2DM) is a chronic disease characterized by metabolic disturbances in specific tissues. The present work aimed to analyze the effects of xanthohumol (XN) and 8-prenylnaringenin (8PN), two beer-derived polyphenols, in liver and skeletal musc …
Type 2 diabetes mellitus (T2DM) is a chronic disease characterized by metabolic disturbances in specific tissues. The present work aimed to …
Therapeutic Application of Micellar Solubilized Xanthohumol in a Western-Type Diet-Induced Mouse Model of Obesity, Diabetes and Non-Alcoholic Fatty Liver Disease.
Mahli A, Seitz T, Freese K, Frank J, Weiskirchen R, Abdel-Tawab M, Behnam D, Hellerbrand C. Mahli A, et al. Cells. 2019 Apr 17;8(4):359. doi: 10.3390/cells8040359. Cells. 2019. PMID: 30999670 Free PMC article.
The objective of this study was to determine whether a micellar solubilization of xanthohumol could enhance the bioavailability and biological efficacy of xanthohumol in a Western-type diet (WTD) induced model of obesity, diabetes and non-alcoholic fatty liver
The objective of this study was to determine whether a micellar solubilization of xanthohumol could enhance the bioavailability and b …
Protective effect of xanthohumol on toxin-induced liver inflammation and fibrosis.
Dorn C, Heilmann J, Hellerbrand C. Dorn C, et al. Int J Clin Exp Pathol. 2012;5(1):29-36. Epub 2012 Jan 1. Int J Clin Exp Pathol. 2012. PMID: 22295144 Free PMC article.
The aim of this study was to investigate the effect of xanthohumol in an acute model of liver injury. Carbon tetrachloride (CCl(4)), an industrial solvent, is a hepatotoxic agent and its administration is widely used as an animal model of toxin-induced liver
The aim of this study was to investigate the effect of xanthohumol in an acute model of liver injury. Carbon tetrachloride (CC …
Xanthohumol exerts protective effects in liver alterations associated with aging.
Fernández-García C, Rancan L, Paredes SD, Montero C, de la Fuente M, Vara E, Tresguerres JAF. Fernández-García C, et al. Eur J Nutr. 2019 Mar;58(2):653-663. doi: 10.1007/s00394-018-1657-6. Epub 2018 Mar 13. Eur J Nutr. 2019. PMID: 29536163
In the present study, the possible protective effects of xanthohumol on liver alterations associated with aging were evaluated. METHODS: Male young and old senescence-accelerated prone mice (SAMP8), aged 2 and 10 months, respectively, were divided into four groups: …
In the present study, the possible protective effects of xanthohumol on liver alterations associated with aging were evaluated …
Anticancer effect of xanthohumol induces growth inhibition and apoptosis of human liver cancer through NF-κB/p53-apoptosis signaling pathway.
Zhao X, Jiang K, Liang B, Huang X. Zhao X, et al. Oncol Rep. 2016 Feb;35(2):669-75. doi: 10.3892/or.2015.4455. Epub 2015 Nov 26. Oncol Rep. 2016. PMID: 26718026 Free PMC article.
Human liver cancer HepG2 cell were treated with 10, 20, 30 and 40 M xanthohumol for 48 h. ...Furthermore, the caspase-3 activity of human liver cancer HepG2 cells was increased by xanthohumol. In addition, 48-h treatment with xanthohumol suppres …
Human liver cancer HepG2 cell were treated with 10, 20, 30 and 40 M xanthohumol for 48 h. ...Furthermore, the caspase-3 activi …
Xanthohumol and 8-prenylnaringenin reduce type 2 diabetes-associated oxidative stress by downregulating galectin-3.
Luís C, Costa R, Rodrigues I, Castela Â, Coelho P, Guerreiro S, Gomes J, Reis C, Soares R. Luís C, et al. Porto Biomed J. 2018 Aug 8;4(1):e23. doi: 10.1016/j.pbj.0000000000000023. eCollection 2019 Jan-Feb. Porto Biomed J. 2018. PMID: 31595252 Free PMC article.
Because natural polyphenols are known to play antioxidant and anti-inflammatory roles and to modulate metabolic activity, we further evaluated the effect of xanthohumol and 8-prenylnaringenin polyphenols in this crosstalk. RESULTS: Gal3 expression was accompanied by 3-nitr …
Because natural polyphenols are known to play antioxidant and anti-inflammatory roles and to modulate metabolic activity, we further evaluat …
79 results