Xanthohumol Pyrazole Derivative Improves Diet-Induced Obesity and Induces Energy Expenditure in High-Fat Diet-Fed Mice.
Paraiso IL, Mattio LM, Alcázar Magaña A, Choi J, Plagmann LS, Redick MA, Miranda CL, Maier CS, Dallavalle S, Kioussi C, Blakemore PR, Stevens JF.
Paraiso IL, et al.
ACS Pharmacol Transl Sci. 2021 Nov 4;4(6):1782-1793. doi: 10.1021/acsptsci.1c00161. eCollection 2021 Dec 10.
ACS Pharmacol Transl Sci. 2021.
PMID: 34927010
Free PMC article.
Here, we investigate the potential of a newly synthesized compound as an inducer of EE for the management of diet-induced obesity and insulin resistance. Xanthohumol (XN), a prenylated flavonoid from hops, was used as a precursor for the synthesis of a pyrazole deri …
Here, we investigate the potential of a newly synthesized compound as an inducer of EE for the management of diet-induced obesity and …