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Prostate and breast cancer cells death induced by xanthohumol investigated with Fourier transform infrared spectroscopy.
Gieroba B, Arczewska M, Sławińska-Brych A, Rzeski W, Stepulak A, Gagoś M. Gieroba B, et al. Spectrochim Acta A Mol Biomol Spectrosc. 2020 Apr 15;231:118112. doi: 10.1016/j.saa.2020.118112. Epub 2020 Jan 25. Spectrochim Acta A Mol Biomol Spectrosc. 2020. PMID: 32014658 Free article.
Fourier Transform Infrared spectroscopy was applied to detect in vitro cell death induced in prostate (PC-3) and breast (T47D) cancer cell lines treated with xanthohumol (XN). ...
Fourier Transform Infrared spectroscopy was applied to detect in vitro cell death induced in prostate (PC-3) and breast (T47D) cancer …
Xanthohumol impairs human prostate cancer cell growth and invasion and diminishes the incidence and progression of advanced tumors in TRAMP mice.
Venè R, Benelli R, Minghelli S, Astigiano S, Tosetti F, Ferrari N. Venè R, et al. Mol Med. 2012 Dec 6;18(1):1292-302. doi: 10.2119/molmed.2012.00174. Mol Med. 2012. PMID: 22952060 Free PMC article.
The long latency and high incidence of prostate carcinogenesis provides the opportunity to intervene with chemoprevention to prevent or eradicate prostate malignancies. In this study, we have used human hormone-resistant prostate cancer cells, DU145 and PC3, …
The long latency and high incidence of prostate carcinogenesis provides the opportunity to intervene with chemoprevention to prevent …
Xanthohumol, a prenylflavonoid derived from hops induces apoptosis and inhibits NF-kappaB activation in prostate epithelial cells.
Colgate EC, Miranda CL, Stevens JF, Bray TM, Ho E. Colgate EC, et al. Cancer Lett. 2007 Feb 8;246(1-2):201-9. doi: 10.1016/j.canlet.2006.02.015. Epub 2006 Mar 24. Cancer Lett. 2007. PMID: 16563612
The purpose of this study was to investigate the anti-tumorigenic effects of xanthohumol (XN), the major prenylflavonoid in hops, on prostate cancer and benign prostate hyperplasia. ...This work suggests that XN and its oxidation product, XAL, may be potentia …
The purpose of this study was to investigate the anti-tumorigenic effects of xanthohumol (XN), the major prenylflavonoid in hops, on …
Growth inhibitory and apoptosis-inducing effects of xanthohumol, a prenylated chalone present in hops, in human prostate cancer cells.
Deeb D, Gao X, Jiang H, Arbab AS, Dulchavsky SA, Gautam SC. Deeb D, et al. Anticancer Res. 2010 Sep;30(9):3333-9. Anticancer Res. 2010. PMID: 20944105 Free PMC article.
Promotion of apoptosis in cancer cells could potentially lead to the regression and improved prognosis of hormone-refractory prostate cancer. Xanthohumol (XN), a prenylated chalcone-derived from hops, has shown strong antitumorigenic activity towards diverse types o …
Promotion of apoptosis in cancer cells could potentially lead to the regression and improved prognosis of hormone-refractory prostate
Highly Cancer Selective Antiproliferative Activity of Natural Prenylated Flavonoids.
Bartmańska A, Tronina T, Popłoński J, Milczarek M, Filip-Psurska B, Wietrzyk J. Bartmańska A, et al. Molecules. 2018 Nov 9;23(11):2922. doi: 10.3390/molecules23112922. Molecules. 2018. PMID: 30423918 Free PMC article.
Nonprenylated naringenin (NG) was used as a model compound. Xanthohumol, alpha,beta-dihydroxanthohumol and 6-prenylnaringenin were the most active compounds. Xanthohumol exhibited higher antiproliferative activity than cisplatin (CP) against five cancer cell lines: …
Nonprenylated naringenin (NG) was used as a model compound. Xanthohumol, alpha,beta-dihydroxanthohumol and 6-prenylnaringenin were th …
Synthesis and Antiproliferative Activity of Minor Hops Prenylflavonoids and New Insights on Prenyl Group Cyclization.
Popłoński J, Turlej E, Sordon S, Tronina T, Bartmańska A, Wietrzyk J, Huszcza E. Popłoński J, et al. Molecules. 2018 Mar 28;23(4):776. doi: 10.3390/molecules23040776. Molecules. 2018. PMID: 29597299 Free PMC article.
Three human cancer cell lines-breast (MCF-7), prostate (PC-3) and colon (HT-29)-were used in antiproliferative assays, with cisplatin as a control compound. Five minor hop prenyl flavonoids and nine non-natural derivatives of xanthohumol have been synthetized. Synth …
Three human cancer cell lines-breast (MCF-7), prostate (PC-3) and colon (HT-29)-were used in antiproliferative assays, with cisplatin …
Treatment of PC-3 and DU145 prostate cancer cells by prenylflavonoids from hop (Humulus lupulus L.) induces a caspase-independent form of cell death.
Delmulle L, Vanden Berghe T, Keukeleire DD, Vandenabeele P. Delmulle L, et al. Phytother Res. 2008 Feb;22(2):197-203. doi: 10.1002/ptr.2286. Phytother Res. 2008. PMID: 17726738
Xanthohumol (X), isoxanthohumol (IX), 8-prenylnaringenin (8PN) and 6-prenylnaringenin (6PN), prenylflavonoids from hop (Humulus lupulus L.), were investigated for their cytotoxicity and the mechanism by which they exert cell death when incubated with prostate cancer
Xanthohumol (X), isoxanthohumol (IX), 8-prenylnaringenin (8PN) and 6-prenylnaringenin (6PN), prenylflavonoids from hop (Humulus lupul
Isoxanthohumol--Biologically active hop flavonoid.
Żołnierczyk AK, Mączka WK, Grabarczyk M, Wińska K, Woźniak E, Anioł M. Żołnierczyk AK, et al. Fitoterapia. 2015 Jun;103:71-82. doi: 10.1016/j.fitote.2015.03.007. Epub 2015 Mar 12. Fitoterapia. 2015. PMID: 25771121
Isoxanthohumol (IXN), apart from xanthohumol (XN) and 8-prenylnaringenin (8PN), is one of the most important prenylflavonoids found in hops. ...IXN exhibits an antiproliferative activity against human cell lines typical for breast cancer (MCF-7), ovarian cancer (A-2780), …
Isoxanthohumol (IXN), apart from xanthohumol (XN) and 8-prenylnaringenin (8PN), is one of the most important prenylflavonoids found i …
Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand-Induced Apoptosis in Prostate Cancer Cells after Treatment with Xanthohumol-A Natural Compound Present in Humulus lupulus L.
Kłósek M, Mertas A, Król W, Jaworska D, Szymszal J, Szliszka E. Kłósek M, et al. Int J Mol Sci. 2016 Jun 22;17(6):837. doi: 10.3390/ijms17060837. Int J Mol Sci. 2016. PMID: 27338375 Free PMC article.
It has ability to selectively kill tumor cells showing no toxicity to normal cells. We tested the apoptotic and cytotoxic activities of xanthohumol, a prenylated chalcone found in Humulus lupulus on androgen-sensitive human prostate adenocarcinoma cells (LNCaP) in c …
It has ability to selectively kill tumor cells showing no toxicity to normal cells. We tested the apoptotic and cytotoxic activities of x
Comprehensive two-dimensional PC-3 prostate cancer cell membrane chromatography for screening anti-tumor components from Radix Sophorae flavescentis.
Wang Q, Xu J, Li X, Zhang D, Han Y, Zhang X. Wang Q, et al. J Sep Sci. 2017 Jul;40(13):2688-2693. doi: 10.1002/jssc.201700208. J Sep Sci. 2017. PMID: 28432774
However, its active components are still ambiguous. We devised a comprehensive two-dimensional PC-3 prostate cancer cell membrane chromatography system for screening anti-prostate cancer components in Radix Sophorae flavescentis. ...Cell proliferation and apoptosis …
However, its active components are still ambiguous. We devised a comprehensive two-dimensional PC-3 prostate cancer cell membrane chr …
16 results