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GABAA Receptor-Mediated Sleep-Promoting Effect of Saaz-Saphir Hops Mixture Containing Xanthohumol and Humulone.
Min B, Ahn Y, Cho HJ, Kwak WK, Suh HJ, Jo K. Min B, et al. Molecules. 2021 Nov 24;26(23):7108. doi: 10.3390/molecules26237108. Molecules. 2021. PMID: 34885687 Free PMC article.
Hops contain flavonoids that have sedative and sleep-promoting activities such as alpha-acid, beta-acid, and xanthohumol. ...Therefore, xanthohumol and humulone contained in the Saaz-Saphir mixture showed sleep-promoting activity mediated by the GABA(A …
Hops contain flavonoids that have sedative and sleep-promoting activities such as alpha-acid, beta-acid, and xanthohumol. ...T …
Challenges of Delirium Management in Patients with Traumatic Brain Injury: From Pathophysiology to Clinical Practice.
Roberson SW, Patel MB, Dabrowski W, Ely EW, Pakulski C, Kotfis K. Roberson SW, et al. Curr Neuropharmacol. 2021;19(9):1519-1544. doi: 10.2174/1570159X19666210119153839. Curr Neuropharmacol. 2021. PMID: 33463474 Free PMC article. Review.
Other potential etiologic contributors include dysregulation of neurotransmission due to intravenous sedatives, seizures, organ failure, sleep cycle disruption or other delirium risk factors. Delirium screening can be accomplished in TBI patients and the presence of deliri …
Other potential etiologic contributors include dysregulation of neurotransmission due to intravenous sedatives, seizures, organ failure, …
Hops for Menopausal Vasomotor Symptoms: Mechanisms of Action.
Abdi F, Mobedi H, Roozbeh N. Abdi F, et al. J Menopausal Med. 2016 Aug;22(2):62-4. doi: 10.6118/jmm.2016.22.2.62. Epub 2016 Aug 30. J Menopausal Med. 2016. PMID: 27617238 Free PMC article.
Menopause is a critical stage of women's life associated with various complaints and distresses. Vasomotor symptoms (VMS), such as hot flushes, night sweats, sleep disturbances, and fatigue, are the most common menopause symptoms affecting about 50% to 80% of middle …
Menopause is a critical stage of women's life associated with various complaints and distresses. Vasomotor symptoms (VMS), such as ho …
Pharmacognostic and pharmacological profile of Humulus lupulus L.
Zanoli P, Zavatti M. Zanoli P, et al. J Ethnopharmacol. 2008 Mar 28;116(3):383-96. doi: 10.1016/j.jep.2008.01.011. Epub 2008 Jan 20. J Ethnopharmacol. 2008. PMID: 18308492 Review.
The female inflorescences of Humulus lupulus (hops), well-known as bittering agent in brewing industry, have long been used in traditional medicine mainly to treat sleep disturbances. However the sedative activity is still under investigation in order to recognize the acti …
The female inflorescences of Humulus lupulus (hops), well-known as bittering agent in brewing industry, have long been used in traditional m …
Valerian/Cascade mixture promotes sleep by increasing non-rapid eye movement (NREM) in rodent model.
Choi HS, Hong KB, Han SH, Suh HJ. Choi HS, et al. Biomed Pharmacother. 2018 Mar;99:913-920. doi: 10.1016/j.biopha.2018.01.159. Epub 2018 Feb 20. Biomed Pharmacother. 2018. PMID: 29710491
The aim of this study was to investigate the beneficial effect of Valerian/Cascade mixture on sleeping in mammal models. In pentobarbital-induced sleep model, Valerian, Cascade, and Valerian/Cascade mixture significantly reduced the latency time for sleeping, …
The aim of this study was to investigate the beneficial effect of Valerian/Cascade mixture on sleeping in mammal models. In pentobarb …
Effect of Valerian/Hop Mixture on Sleep-Related Behaviors in Drosophila melanogaster.
Choi HS, Ko BS, Kim HD, Hong KB, Suh HJ. Choi HS, et al. Biol Pharm Bull. 2017;40(7):1101-1110. doi: 10.1248/bpb.b17-00262. Biol Pharm Bull. 2017. PMID: 28674253 Free article.
The aim of this study was to investigate the sleep-promoting effect of a Valerian/Hops mixture in fruit flies. ...This study demonstrates that a Valerian/Cascade mixture extract improves sleep-related behaviors, including sleeping time, by modulating GABAergi …
The aim of this study was to investigate the sleep-promoting effect of a Valerian/Hops mixture in fruit flies. ...This study demonstr …
Positive allosteric modulation of native and recombinant GABAA receptors by hops prenylflavonoids.
Benkherouf AY, Soini SL, Stompor M, Uusi-Oukari M. Benkherouf AY, et al. Eur J Pharmacol. 2019 Jun 5;852:34-41. doi: 10.1016/j.ejphar.2019.02.034. Epub 2019 Feb 21. Eur J Pharmacol. 2019. PMID: 30797788
In addition to its wide range of bioactivity, it exhibits neuroactive properties as a sedative and sleeping aid. The compounds responsible for this activity are yet to be revealed and understood in terms of their pharmacological properties. ...Flumazenil sensitivity of GAB …
In addition to its wide range of bioactivity, it exhibits neuroactive properties as a sedative and sleeping aid. The compounds respon …
Hop (Humulus lupulus L.) Extract and 6-Prenylnaringenin Induce P450 1A1 Catalyzed Estrogen 2-Hydroxylation.
Wang S, Dunlap TL, Howell CE, Mbachu OC, Rue EA, Phansalkar R, Chen SN, Pauli GF, Dietz BM, Bolton JL. Wang S, et al. Chem Res Toxicol. 2016 Jul 18;29(7):1142-50. doi: 10.1021/acs.chemrestox.6b00112. Epub 2016 Jun 22. Chem Res Toxicol. 2016. PMID: 27269377 Free PMC article.
(hops) is a popular botanical dietary supplement used by women as a sleep aid and for postmenopausal symptom relief. In addition to its efficacy for menopausal symptoms, hops can also modulate the chemical estrogen carcinogenesis pathway and potentially protect women from …
(hops) is a popular botanical dietary supplement used by women as a sleep aid and for postmenopausal symptom relief. In addition to i …