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2001 1
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Xanthohumol from Humulus lupulus L. potentiates the killing of Mycobacterium tuberculosis and mitigates liver toxicity by the combination of isoniazid in mouse tuberculosis models.
Lou H, Zhang F, Lu L, Ding Y, Hao X. Lou H, et al. RSC Adv. 2020 Apr 1;10(22):13223-13231. doi: 10.1039/c9ra10347c. eCollection 2020 Mar 30. RSC Adv. 2020. PMID: 35492081 Free PMC article.
During the experiment, the uninfected group and the normal control group received an equal volume of saline, the xanthohumol group received an equal volume of xanthohumol only, and the isoniazid group received an equal volume of isoniazid only. ...In conclusion, …
During the experiment, the uninfected group and the normal control group received an equal volume of saline, the xanthohumol group re …
Microbial Conjugation Studies of Licochalcones and Xanthohumol.
Han F, Xiao Y, Lee IS. Han F, et al. Int J Mol Sci. 2021 Jun 26;22(13):6893. doi: 10.3390/ijms22136893. Int J Mol Sci. 2021. PMID: 34206985 Free PMC article.
Microbial conjugation studies of licochalcones (1-4) and xanthohumol (5) were performed by using the fungi Mucor hiemalis and Absidia coerulea. ...These results could contribute to a better understanding of the metabolic fates of licochalcones and xanthohumol in mam …
Microbial conjugation studies of licochalcones (1-4) and xanthohumol (5) were performed by using the fungi Mucor hiemalis and Absidia …
Nobiletin and Xanthohumol Sensitize Colorectal Cancer Stem Cells to Standard Chemotherapy.
Turdo A, Glaviano A, Pepe G, Calapà F, Raimondo S, Fiori ME, Carbone D, Basilicata MG, Di Sarno V, Ostacolo C, Parrino B, Cascioferro S, Pecoraro C, Di Franco S, Bellavia D, Gaggianesi M, Veschi V, Lo Iacono M, Ganduscio G, Pantina VD, Mangiapane LR, Bongiorno MR, Alessandro R, Todaro M, De Maria R, Diana P, Campiglia P, Stassi G. Turdo A, et al. Cancers (Basel). 2021 Aug 4;13(16):3927. doi: 10.3390/cancers13163927. Cancers (Basel). 2021. PMID: 34439086 Free PMC article.
Colorectal cancer (CRC) mortality is mainly caused by patient refractoriness to common anti-cancer therapies and consequent metastasis formation. Besides, the notorious toxic side effects of chemotherapy are a concurrent obstacle to be tackled. ...The natural biofunctional …
Colorectal cancer (CRC) mortality is mainly caused by patient refractoriness to common anti-cancer therapies and consequent metastasis forma …
Reductive Metabolism of Xanthohumol and 8-Prenylnaringenin by the Intestinal Bacterium Eubacterium ramulus.
Paraiso IL, Plagmann LS, Yang L, Zielke R, Gombart AF, Maier CS, Sikora AE, Blakemore PR, Stevens JF. Paraiso IL, et al. Mol Nutr Food Res. 2019 Jan;63(2):e1800923. doi: 10.1002/mnfr.201800923. Epub 2018 Dec 3. Mol Nutr Food Res. 2019. PMID: 30471194 Free PMC article.
Microbial catabolites of polyphenols can contribute in significant ways to the health-promoting properties of their parent polyphenols. This work aims to identify intestinal metabolites of xanthohumol (XN), a prenylated flavonoid found in hops (Humulus lupulus) and beer, a …
Microbial catabolites of polyphenols can contribute in significant ways to the health-promoting properties of their parent polyphenols. This …
Amyloid-β Aggregation Inhibitory and Neuroprotective Effects of Xanthohumol and its Derivatives for Alzheimer's Diseases.
Wang X, Ho SL, Poon CY, Yan T, Li HW, Wong MS. Wang X, et al. Curr Alzheimer Res. 2019;16(9):836-842. doi: 10.2174/1567205016666190827123222. Curr Alzheimer Res. 2019. PMID: 31453789
However, the bio-incompatibility and blood-brain barrier impermeability of xanthohumol hindered its in vivo efficacy potential for treating Alzheimer's disease (AD). ...CONCLUSION: Two derivatives have been identified to be biocompatible, non-toxic, neuroprot …
However, the bio-incompatibility and blood-brain barrier impermeability of xanthohumol hindered its in vivo efficacy potential for tr …
Dose-Dependent Protective and Inductive Effects
of Xanthohumol on Oxidative DNA Damage in
Saccharomyces cerevisiae.
Carvalho DO, Oliveira R, Johansson B, Guido LF. Carvalho DO, et al. Food Technol Biotechnol. 2016 Mar;54(1):60-69. doi: 10.17113/ftb.54.01.16.4256. Food Technol Biotechnol. 2016. PMID: 27904394 Free PMC article.
Yeast cultures under oxidative stress, induced by H(2)O(2), displayed stronger growth in the presence of 5 mg/L of xanthohumol than cultures with only H(2)O(2). Likewise, DNA damage assessed by the comet assay was significantly lower in cells co-incubated with xanthohum …
Yeast cultures under oxidative stress, induced by H(2)O(2), displayed stronger growth in the presence of 5 mg/L of xanthohumol than c …
Xanthohumol ameliorates 2,3,7,8-tetrachlorodibenzo-p-dioxin-induced cellular toxicity in cultured MC3T3-E1 osteoblastic cells.
Suh KS, Choi EM, Kim HS, Park SY, Chin SO, Rhee SY, Pak YK, Choe W, Ha J, Chon S. Suh KS, et al. J Appl Toxicol. 2018 Jul;38(7):1036-1046. doi: 10.1002/jat.3613. Epub 2018 Mar 8. J Appl Toxicol. 2018. PMID: 29516522
The aim of the current study was to explore the role of xanthohumol in modulating the toxicity of TCDD in MC3T3-E1 osteoblastic cells. ...We conclude that xanthohumol has a beneficial influence and may antagonize TCDD toxicity in osteoblastic cells....
The aim of the current study was to explore the role of xanthohumol in modulating the toxicity of TCDD in MC3T3-E1 osteoblasti …
Xanthohumol feeding does not impair organ function and homoeostasis in mice.
Dorn C, Bataille F, Gaebele E, Heilmann J, Hellerbrand C. Dorn C, et al. Food Chem Toxicol. 2010 Jul;48(7):1890-7. doi: 10.1016/j.fct.2010.04.030. Epub 2010 Apr 26. Food Chem Toxicol. 2010. PMID: 20427021
Here, we fed female BALB/c mice with a standard diet supplemented with xanthohumol for 3 weeks, and thus, achieved a daily dose of approximately 1000 mg xanthohumol/kg body weight. There were no significant differences in body weight or food intake between mice on s …
Here, we fed female BALB/c mice with a standard diet supplemented with xanthohumol for 3 weeks, and thus, achieved a daily dose of ap …
Xanthohumol Protects Morphology and Function in a Mouse Model of Retinal Degeneration.
Henneman NF, Foster SL, Chrenek MA, Sellers JT, Wright CB, Schmidt RH, Nickerson JM, Boatright JH. Henneman NF, et al. Invest Ophthalmol Vis Sci. 2018 Jan 1;59(1):45-53. doi: 10.1167/iovs.17-22132. Invest Ophthalmol Vis Sci. 2018. PMID: 29305606 Free PMC article.
PURPOSE: To investigate whether treatment with xanthohumol (XN), the principal prenylated chalconoid from Humulus lupulus (hops), is protective in a mouse model of light-induced retinal degeneration (LIRD). METHODS: Mice (129S2/SvPasCrl) were intraperitoneally injected wit …
PURPOSE: To investigate whether treatment with xanthohumol (XN), the principal prenylated chalconoid from Humulus lupulus (hops), is …
Protective effect of xanthohumol on toxin-induced liver inflammation and fibrosis.
Dorn C, Heilmann J, Hellerbrand C. Dorn C, et al. Int J Clin Exp Pathol. 2012;5(1):29-36. Epub 2012 Jan 1. Int J Clin Exp Pathol. 2012. PMID: 22295144 Free PMC article.
Xanthohumol, the major prenylated chalcone found in hops, is known for its anti-inflammatory properties. ...Furthermore, xanthohumol fed mice revealed decreased hepatic NFkappaB activity. These results suggest that the protective effects of xanthohumol in thi …
Xanthohumol, the major prenylated chalcone found in hops, is known for its anti-inflammatory properties. ...Furthermore, xanthohum …
59 results