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Page 1
Prenylated Flavonoids in Topical Infections and Wound Healing.
Sychrová A, Škovranová G, Čulenová M, Bittner Fialová S. Sychrová A, et al. Molecules. 2022 Jul 13;27(14):4491. doi: 10.3390/molecules27144491. Molecules. 2022. PMID: 35889363 Free PMC article. Review.
A total of 127 structurally diverse flavonoids showed promising antimicrobial activity against pathogens affecting wound healing, predominantly Staphylococcus aureus strains, but only artocarpin, diplacone, isobavachalcone, licochalcone A, sophoraflavanone G, and …
A total of 127 structurally diverse flavonoids showed promising antimicrobial activity against pathogens affecting wound healing …
Dietary prenylated flavonoid xanthohumol alleviates oxidative damage and accelerates diabetic wound healing via Nrf2 activation.
Lu X, Liu M, Dong H, Miao J, Stagos D, Liu M. Lu X, et al. Food Chem Toxicol. 2022 Feb;160:112813. doi: 10.1016/j.fct.2022.112813. Epub 2022 Jan 6. Food Chem Toxicol. 2022. PMID: 34999176
In the present study, we reported XN alleviates oxidative damage and accelerates diabetic wound healing via Nrf2 activation. In vitro, XN attenuated hydrogen peroxide (H(2)O(2))-induced cytotoxicity, ROS production, cell apoptosis, as well as high glucose-induced ce …
In the present study, we reported XN alleviates oxidative damage and accelerates diabetic wound healing via Nrf2 activation. I …
A Novel Look at Mechanisms and Applications of Xanthohumol (XN) in Dermatology and Cosmetology.
Kołodziejczak A, Dziedzic M, Algiert-Zielińska B, Mucha P, Rotsztejn H. Kołodziejczak A, et al. Int J Mol Sci. 2024 Nov 6;25(22):11938. doi: 10.3390/ijms252211938. Int J Mol Sci. 2024. PMID: 39596008 Free PMC article. Review.
Xanthohumol (XN), representing the group of chalcones, is a hydroxyl and superoxide free radical scavenger. ...It has also been recognized that XN intake could affect diabetic wound healing. XN shows antitumoral activity, e.g., in the case of skin melanoma, w …
Xanthohumol (XN), representing the group of chalcones, is a hydroxyl and superoxide free radical scavenger. ...It has also been recog …
Xanthohumol modulates inflammation, oxidative stress, and angiogenesis in type 1 diabetic rat skin wound healing.
Costa R, Negrão R, Valente I, Castela Â, Duarte D, Guardão L, Magalhães PJ, Rodrigues JA, Guimarães JT, Gomes P, Soares R. Costa R, et al. J Nat Prod. 2013 Nov 22;76(11):2047-53. doi: 10.1021/np4002898. Epub 2013 Nov 7. J Nat Prod. 2013. PMID: 24200239
This study has evaluated the effect of phenol-rich beverage consumption in diabetic rats on wound healing, through angiogenesis, inflammation, and oxidative stress modulation. A wound-healing assay was performed in streptozotocin-induced diabetic Wista …
This study has evaluated the effect of phenol-rich beverage consumption in diabetic rats on wound healing, through angiogenesi …
Xanthohumol-supplemented beer modulates angiogenesis and inflammation in a skin wound healing model. Involvement of local adipocytes.
Negrão R, Costa R, Duarte D, Gomes TT, Coelho P, Guimarães JT, Guardão L, Azevedo I, Soares R. Negrão R, et al. J Cell Biochem. 2012 Jan;113(1):100-9. doi: 10.1002/jcb.23332. J Cell Biochem. 2012. PMID: 21898537
Angiogenesis and inflammation are two intermingled processes that play a role in wound healing. Nevertheless, whenever exacerbated, these processes result in nonhealing wounds. ...This study shows that XN intake in its natural beer context reduced inflammation, oxid …
Angiogenesis and inflammation are two intermingled processes that play a role in wound healing. Nevertheless, whenever exacerb …
Do Curdlan Hydrogels Improved with Bioactive Compounds from Hop Exhibit Beneficial Properties for Skin Wound Healing?
Nurzynska A, Klimek K, Michalak A, Dos Santos Szewczyk K, Arczewska M, Szalaj U, Gagos M, Ginalska G. Nurzynska A, et al. Int J Mol Sci. 2023 Jun 18;24(12):10295. doi: 10.3390/ijms241210295. Int J Mol Sci. 2023. PMID: 37373441 Free PMC article.
It is known that biomaterials composed of biopolymers can significantly promote the process of wound healing and regeneration. The aim of this study was to establish whether curdlan-based biomaterials modified with hop compounds can be considered as promising candid …
It is known that biomaterials composed of biopolymers can significantly promote the process of wound healing and regeneration. …
Semi-synthesis and in vitro anti-cancer effects evaluation of novel xanthohumol derivatives.
Sun X, Chen J, Huang D, Ding F, Zhao L, Li HM, Wang XS, Zhang YX, Wu CZ. Sun X, et al. Mol Divers. 2024 Oct;28(5):2749-2758. doi: 10.1007/s11030-023-10706-7. Epub 2023 Dec 8. Mol Divers. 2024. PMID: 38064107
Xanthohumol (Xn) is a chalcone compound isolated from Humulus lupulus Linn., that has various biological activities. ...Among these compounds, 2-((E)-2,4-dihydroxy-5-((E)-3-(4-hydroxyphenyl)acryloyl)-6-methoxy-3-(3- methylbut-2-en-1-yl)benzylidene)hydrazine-1-carboximidami …
Xanthohumol (Xn) is a chalcone compound isolated from Humulus lupulus Linn., that has various biological activities. ...Among these c …
Xanthohumol Blocks Proliferation and Migration of Vascular Smooth Muscle Cells in Vitro and Reduces Neointima Formation in Vivo.
Liu R, Heiss EH, Schachner D, Jiang B, Liu W, Breuss JM, Dirsch VM, Atanasov AG. Liu R, et al. J Nat Prod. 2017 Jul 28;80(7):2146-2150. doi: 10.1021/acs.jnatprod.7b00268. Epub 2017 Jun 19. J Nat Prod. 2017. PMID: 28627872 Free PMC article.
Xanthohumol (1) is a principal prenylated chalcone found in hops. The aim of this study was to examine its influence on platelet-derived growth factor (PDGF)-BB-triggered vascular smooth muscle cell (VSMC) proliferation and migration in vitro and on experimentally induced …
Xanthohumol (1) is a principal prenylated chalcone found in hops. The aim of this study was to examine its influence on platelet-deri …
Xanthohumol Regulates Mitophagy in Osteosarcoma Cells via AMPK-ULK1-FUNDC1 Signaling Pathway.
Ge Q, Yan Z, Tian Q, Zhang J, Li J, Cai F, Zhang L, Zhu Y. Ge Q, et al. Phytother Res. 2025 May;39(5):2393-2406. doi: 10.1002/ptr.8468. Epub 2025 Apr 7. Phytother Res. 2025. PMID: 40190139
The therapeutic efficacy for OS patients has remained stagnant in recent decades. Xanthohumol (XN), a flavonoid naturally found in hops, has demonstrated significant anticancer properties in lung and breast cancer. ...Firstly, we assessed the impact of XN on OS cell prolif …
The therapeutic efficacy for OS patients has remained stagnant in recent decades. Xanthohumol (XN), a flavonoid naturally found in ho …
Angiogenesis and inflammation signaling are targets of beer polyphenols on vascular cells.
Negrão R, Costa R, Duarte D, Taveira Gomes T, Mendanha M, Moura L, Vasques L, Azevedo I, Soares R. Negrão R, et al. J Cell Biochem. 2010 Dec 1;111(5):1270-9. doi: 10.1002/jcb.22850. J Cell Biochem. 2010. PMID: 20803553
Opposite in vitro effects were observed between 8PN, stimulating endothelial and smooth muscle cell (SMC) growth, motility, invasion and capillary-like structures formation, and XN and IXN, which inhibited them. Mouse matrigel plug and rat skin wound-healing assays …
Opposite in vitro effects were observed between 8PN, stimulating endothelial and smooth muscle cell (SMC) growth, motility, invasion and cap …
11 results