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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1943 1
1946 1
1947 7
1948 3
1949 4
1950 8
1951 6
1952 8
1953 5
1954 1
1955 9
1956 5
1957 4
1958 7
1959 2
1960 9
1961 3
1962 6
1963 9
1964 8
1965 11
1966 5
1967 11
1968 15
1969 16
1970 14
1971 12
1972 20
1973 19
1974 17
1975 32
1976 36
1977 34
1978 25
1979 24
1980 26
1981 24
1982 25
1983 17
1984 18
1985 19
1986 20
1987 20
1988 22
1989 19
1990 25
1991 28
1992 33
1993 28
1994 38
1995 33
1996 40
1997 43
1998 52
1999 32
2000 51
2001 67
2002 88
2003 99
2004 109
2005 129
2006 148
2007 153
2008 203
2009 221
2010 215
2011 236
2012 283
2013 303
2014 325
2015 307
2016 289
2017 328
2018 331
2019 334
2020 322
2021 332
2022 310
2023 277
2024 293
2025 328
2026 190

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6,439 results

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Page 1
Bioactive Marine Xanthones: A Review.
Soares JX, Loureiro DRP, Dias AL, Reis S, Pinto MMM, Afonso CMM. Soares JX, et al. Mar Drugs. 2022 Jan 8;20(1):58. doi: 10.3390/md20010058. Mar Drugs. 2022. PMID: 35049913 Free PMC article. Review.
In this work, a comprehensive literature review of marine xanthones reported up to now was performed. A large number of bioactive xanthone derivatives (169) were identified, and their structures, biological activities, and natural sources were described. ...Moreover …
In this work, a comprehensive literature review of marine xanthones reported up to now was performed. A large number of bioactive …
Xanthones as P-glycoprotein modulators and their impact on drug bioavailability.
Silva V, Gil-Martins E, Silva B, Rocha-Pereira C, Sousa ME, Remião F, Silva R. Silva V, et al. Expert Opin Drug Metab Toxicol. 2021 Apr;17(4):441-482. doi: 10.1080/17425255.2021.1861247. Epub 2021 Apr 20. Expert Opin Drug Metab Toxicol. 2021. PMID: 33283552 Review.
P-gp can be modulated by different molecules - including xanthone derivatives - to surpass the multidrug resistance (MDR) phenomenon through P-gp inhibition, or to serve as an antidotal strategy in intoxication scenarios through P-gp induction/activation.Areas covered: Thi …
P-gp can be modulated by different molecules - including xanthone derivatives - to surpass the multidrug resistance (MDR) phenomenon …
Xanthones as neuroprotective agents: A comprehensive review of their role in the prevention and treatment of neurodegenerative diseases.
Das D, Das A, Bhattacharya K, Koch KP, Deuri DJ, Saikia D, Chanu NR, Deka S. Das D, et al. Ageing Res Rev. 2025 Jul;109:102772. doi: 10.1016/j.arr.2025.102772. Epub 2025 May 17. Ageing Res Rev. 2025. PMID: 40389171 Review.
Despite extensive studies, no xanthone-based molecule has successfully progressed through clinical trials to reach pharmaceutical applications. ...Existing literature has been rigorously examined to highlight the pharmacological relevance of xanthones in these disor …
Despite extensive studies, no xanthone-based molecule has successfully progressed through clinical trials to reach pharmaceutical app …
Xanthones from mangosteen (Garcinia mangostana): multi-targeting pharmacological properties.
Jindarat S. Jindarat S. J Med Assoc Thai. 2014 Feb;97 Suppl 2:S196-201. J Med Assoc Thai. 2014. PMID: 25518194 Review.
The search terms included mangosteen, xanthone, mangostin, and gatanin in all of the human, animal, in vitro and in vivo studies. Anti-intflammation, antioxidant, antibacterial, anticancer and antiulcer properties of each substance were the key parameters. RESULTS: Xant …
The search terms included mangosteen, xanthone, mangostin, and gatanin in all of the human, animal, in vitro and in vivo studies. Ant …
Synthesis of xanthones: an overview.
Sousa ME, Pinto MM. Sousa ME, et al. Curr Med Chem. 2005;12(21):2447-79. doi: 10.2174/092986705774370736. Curr Med Chem. 2005. PMID: 16250872 Review.
Thus, the purpose of this review is to report some recent improvements of the classical synthetic methods as well as of some non-classical methods to obtain simple oxygenated xanthones. The strategies for introduction of substituents into the xanthonic nucleus are a …
Thus, the purpose of this review is to report some recent improvements of the classical synthetic methods as well as of some non-classical m …
Recent Advances on Natural and Non-Natural Xanthones as Potential Anticancer Agents: A Review.
Gogoi U, Pathak K, Saikia R, Pathak MP, Paul T, Khan SA, Das A. Gogoi U, et al. Med Chem. 2023;19(8):757-784. doi: 10.2174/1573406419666221226093311. Med Chem. 2023. PMID: 36573047 Review.
OBJECTIVE: The objective of this review is to comprehensively highlight the main natural and nonnatural sources of xanthones having potential anti-cancer effects along with their key structural elements, structure-activity relationships (SARs), mechanisms of action, and ep …
OBJECTIVE: The objective of this review is to comprehensively highlight the main natural and nonnatural sources of xanthones having p …
Xanthones and Xanthone O-beta-D-Glucosides from the Roots of Polygala azizsancarii Donmez.
Çalış İ, Ünlü A, Uğurlu Aydın Z, Dönmez AA, Soliman Yusufoğlu H, Jurt S, Linden A. Çalış İ, et al. Chem Biodivers. 2022 Aug;19(8):e202200499. doi: 10.1002/cbdv.202200499. Epub 2022 Jul 21. Chem Biodivers. 2022. PMID: 35797203 Free article.
Nine xanthone derivatives (1-9) were isolated from the roots of Polygala azizsancarii, which is a narrow endemic species for the flora of Turkiye. Based on all of the evidence, the structures of 1-9 were established as two previously undescribed xanthone O-glucoside …
Nine xanthone derivatives (1-9) were isolated from the roots of Polygala azizsancarii, which is a narrow endemic species for the flor …
Xanthones from Calophyllum Polyanthum Wallich ex Choisy with CYP1 Enzymes Inhibitory Activity.
Cao TT, Huang RY, Li X, Yang TY, Xie HD, Shen YH, Li F, Li X. Cao TT, et al. Chem Biodivers. 2022 Jun;19(6):e202200268. doi: 10.1002/cbdv.202200268. Epub 2022 May 27. Chem Biodivers. 2022. PMID: 35531592
Three new xanthone compounds, 1,3,5-trihydroxy-2-(2-hydroxy-3-methylbut-3-enyl)-4-(3-methylbut-2-enyl)xanthone (1), toxyloxanthone E (2), dehydrocycloguanandin B (3) along with 15 known xanthones (4-18) were isolated from the aerial parts of Calophyllum polya …
Three new xanthone compounds, 1,3,5-trihydroxy-2-(2-hydroxy-3-methylbut-3-enyl)-4-(3-methylbut-2-enyl)xanthone (1), toxyloxant …
Tetraoxygenated naturally occurring xanthones.
Peres V, Nagem TJ, de Oliveira FF. Peres V, et al. Phytochemistry. 2000 Dec;55(7):683-710. doi: 10.1016/s0031-9422(00)00303-4. Phytochemistry. 2000. PMID: 11190384 Review.
This review, with 350 references, gives information on the chemical study of 234 naturally occurring tetraoxygenated xanthones in 12 families, 53 genus and 182 species of higher plants, and two which are described as fungal and lichen metabolites. ...
This review, with 350 references, gives information on the chemical study of 234 naturally occurring tetraoxygenated xanthones in 12 …
Current status and perspectives of xanthones production using cultured plant biocatalyst models aided by in-silico tools for its optimization.
Khattab AR, Farag MA. Khattab AR, et al. Crit Rev Biotechnol. 2020 May;40(3):415-431. doi: 10.1080/07388551.2020.1721426. Epub 2020 Feb 13. Crit Rev Biotechnol. 2020. PMID: 32054338 Review.
Recent advances in xanthones biosynthetic pathways are outlined and their metabolic engineering. This review summarizes the state-of-the-art processes for the biotechnological production of xanthones, its limitations, and potential improvements. The in vitro tissue …
Recent advances in xanthones biosynthetic pathways are outlined and their metabolic engineering. This review summarizes the state-of- …
6,439 results