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2012 5
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OAE: The Ontology of Adverse Events.
He Y, Sarntivijai S, Lin Y, Xiang Z, Guo A, Zhang S, Jagannathan D, Toldo L, Tao C, Smith B. He Y, et al. J Biomed Semantics. 2014 Jul 5;5:29. doi: 10.1186/2041-1480-5-29. eCollection 2014. J Biomed Semantics. 2014. PMID: 25093068 Free PMC article.
OAE has been used in the analysis of several different sorts of vaccine and drug adverse event data. For example, using the data extracted from the Vaccine Adverse Event Reporting System (VAERS), OAE was used to analyse vaccine adverse events
OAE has been used in the analysis of several different sorts of vaccine and drug adverse event data. For example, using the da …
Vaccine and Drug Ontology Studies (VDOS 2014).
Tao C, He Y, Arabandi S. Tao C, et al. Among authors: he y. J Biomed Semantics. 2016 Feb 25;7:6. doi: 10.1186/s13326-015-0039-8. eCollection 2016. J Biomed Semantics. 2016. PMID: 26918107 Free PMC article.
Over the last decade, tremendous efforts have been made in the biomedical ontology community to ontologically represent various areas associated with vaccines and drugs - extending existing clinical terminology systems such as SNOMED, RxNorm, NDF-RT, and MedDRA, developing new mo …
Over the last decade, tremendous efforts have been made in the biomedical ontology community to ontologically represent various areas associ …
The Ontology of Vaccine Adverse Events (OVAE) and its usage in representing and analyzing adverse events associated with US-licensed human vaccines.
Marcos E, Zhao B, He Y. Marcos E, et al. Among authors: he y. J Biomed Semantics. 2013 Nov 26;4(1):40. doi: 10.1186/2041-1480-4-40. J Biomed Semantics. 2013. PMID: 24279920 Free PMC article.
Many known vaccine adverse events (VAEs) have been recorded in the package inserts of US-licensed commercial vaccine products. To better represent and analyze VAEs, we developed the Ontology of Vaccine Adverse Events (OVAE) as an extension of the Ontol …
Many known vaccine adverse events (VAEs) have been recorded in the package inserts of US-licensed commercial vaccine products. …
ODAE: Ontology-based systematic representation and analysis of drug adverse events and its usage in study of adverse events given different patient age and disease conditions.
Yu H, Nysak S, Garg N, Ong E, Ye X, Zhang X, He Y. Yu H, et al. Among authors: he y. BMC Bioinformatics. 2019 May 1;20(Suppl 7):199. doi: 10.1186/s12859-019-2729-1. BMC Bioinformatics. 2019. PMID: 31074377 Free PMC article.
BACKGROUND: Drug adverse events (AEs), or called adverse drug events (ADEs), are ranked one of the leading causes of mortality. The Ontology of Adverse Events (OAE) has been widely used for adverse event AE representation, s …
BACKGROUND: Drug adverse events (AEs), or called adverse drug events (ADEs), are ranked one of the leading cause …
Ontology-based Precision Vaccinology for Deep Mechanism Understanding and Precision Vaccine Development.
Xie J, Zi W, Li Z, He Y. Xie J, et al. Among authors: he y. Curr Pharm Des. 2021;27(7):900-910. doi: 10.2174/1381612826666201125112131. Curr Pharm Des. 2021. PMID: 33238868 Review.
However, effective and safe vaccines still do not exist for many diseases, and where vaccines exist, their protective immune mechanisms are often unclear. Although licensed vaccines are generally safe, various adverse events, and sometimes severe adverse e
However, effective and safe vaccines still do not exist for many diseases, and where vaccines exist, their protective immune mechanisms are …
Ontology-Based Vaccine Adverse Event Representation and Analysis.
Xie J, He Y. Xie J, et al. Among authors: he y. Adv Exp Med Biol. 2017;1028:89-103. doi: 10.1007/978-981-10-6041-0_6. Adv Exp Med Biol. 2017. PMID: 29058218 Review.
In the past decades, different controlled terminologies, including the Medical Dictionary for Regulatory Activities (MedDRA) (Brown EG, Wood L, Wood S, et al., Drug Saf 20(2):109-117, 1999), the Common Terminology Criteria for Adverse Events (CTCAE) (NCI, The …
In the past decades, different controlled terminologies, including the Medical Dictionary for Regulatory Activities (MedDRA) (Brown EG, Wood …
Profiling COVID-19 Vaccine Adverse Events by Statistical and Ontological Analysis of VAERS Case Reports.
Guo W, Deguise J, Tian Y, Huang PC, Goru R, Yang Q, Peng S, Zhang L, Zhao L, Xie J, He Y. Guo W, et al. Among authors: he y. Front Pharmacol. 2022 Jun 24;13:870599. doi: 10.3389/fphar.2022.870599. eCollection 2022. Front Pharmacol. 2022. PMID: 35814246 Free PMC article.
These vaccines have been effective in reducing the rate and severity of COVID-19 infection but also have been associated with various adverse events (AEs). In this study, data from the Vaccine Adverse Event Reporting System (VAERS) was queried and anal …
These vaccines have been effective in reducing the rate and severity of COVID-19 infection but also have been associated with various adv
Ontology-based combinatorial comparative analysis of adverse events associated with killed and live influenza vaccines.
Sarntivijai S, Xiang Z, Shedden KA, Markel H, Omenn GS, Athey BD, He Y. Sarntivijai S, et al. Among authors: he y. PLoS One. 2012;7(11):e49941. doi: 10.1371/journal.pone.0049941. Epub 2012 Nov 28. PLoS One. 2012. PMID: 23209624 Free PMC article.
Vaccine adverse events (VAEs) are adverse bodily changes occurring after vaccination. Understanding the adverse event (AE) profiles is a crucial step to identify serious AEs. ...
Vaccine adverse events (VAEs) are adverse bodily changes occurring after vaccination. Understanding the adverse
A statistical analysis of vaccine-adverse event data.
Ren JJ, Sun T, He Y, Zhang Y. Ren JJ, et al. Among authors: he y. BMC Med Inform Decis Mak. 2019 May 28;19(1):101. doi: 10.1186/s12911-019-0818-8. BMC Med Inform Decis Mak. 2019. PMID: 31138219 Free PMC article.
BACKGROUND: Vaccination has been one of the most successful public health interventions to date, and the U.S. FDA/CDC Vaccine Adverse Event Reporting System (VAERS) currently contains more than 500,000 reports for post-vaccination adverse events
BACKGROUND: Vaccination has been one of the most successful public health interventions to date, and the U.S. FDA/CDC Vaccine Adve
Ontology-Based Meta-Analysis of Animal and Human Adverse Events Associated With Licensed Brucellosis Vaccines.
Xie J, Wang J, Li Z, Wang W, Pang Y, He Y. Xie J, et al. Among authors: he y. Front Pharmacol. 2018 May 15;9:503. doi: 10.3389/fphar.2018.00503. eCollection 2018. Front Pharmacol. 2018. PMID: 29867505 Free PMC article.
Our meta-analysis identified 20 animal AEs and 46 human AEs associated with the three vaccines. Based on the Ontology of Adverse Events (OAE) hierarchical classification, these animal AEs were enriched in the immune and reproductive systems that might eventually res …
Our meta-analysis identified 20 animal AEs and 46 human AEs associated with the three vaccines. Based on the Ontology of Adverse E
39 results