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Pediatric and adult patients with ME/CFS following COVID-19: A structured approach to diagnosis using the Munich Berlin Symptom Questionnaire (MBSQ).
Peo LC, Wiehler K, Paulick J, Gerrer K, Leone A, Viereck A, Haegele M, Stojanov S, Warlitz C, Augustin S, Alberer M, Hattesohl DBR, Froehlich L, Scheibenbogen C, Jason LA, Mihatsch LL, Pricoco R, Behrends U. Peo LC, et al. Eur J Pediatr. 2024 Mar;183(3):1265-1276. doi: 10.1007/s00431-023-05351-z. Epub 2023 Dec 14. Eur J Pediatr. 2024. PMID: 38095713 Free PMC article.
A subset of patients with post-COVID-19 condition (PCC) fulfill the clinical criteria of myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS). To establish the diagnosis of ME/CFS for clinical and research purposes, comprehensive scores have to be evaluated. …
A subset of patients with post-COVID-19 condition (PCC) fulfill the clinical criteria of myalgic encephalomyelitis/chronic fatigue
Does the effect of cognitive behavior therapy for chronic fatigue syndrome (ME/CFS) vary by patient characteristics? A systematic review and individual patient data meta-analysis.
Kuut TA, Buffart LM, Braamse AMJ, Csorba I, Bleijenberg G, Nieuwkerk P, Moss-Morris R, Müller F, Knoop H. Kuut TA, et al. Psychol Med. 2024 Feb;54(3):447-456. doi: 10.1017/S0033291723003148. Epub 2023 Nov 6. Psychol Med. 2024. PMID: 37927223 Review.
Debate is ongoing on the efficacy of cognitive behavior therapy (CBT) for myalgic encephalomyelitis or chronic fatigue syndrome (ME/CFS). With an individual patient data (IPD) meta-analysis we investigated whether the effect of CBT varied by patient characteristics. …
Debate is ongoing on the efficacy of cognitive behavior therapy (CBT) for myalgic encephalomyelitis or chronic fatigue syndrom …
Correlates of burnout among healthcare workers during the COVID-19 pandemic in South Korea.
Hwang S, Kwon KT, Lee SH, Kim SW, Chang HH, Kim Y, Bae S, Cheong HS, Park SY, Kim B, Lee S, Park J, Heo ST, Oh WS, Kim Y, Park KH, Kang CK, Oh N, Lim SJ, Yun S, Son JW, Ryoo HW, Chung US, Lee JY, Park HY, Shin JY, Bae SG, Lee JY. Hwang S, et al. Sci Rep. 2023 Feb 27;13(1):3360. doi: 10.1038/s41598-023-30372-x. Sci Rep. 2023. PMID: 36849638 Free PMC article.
OLBI results indicate clinically exhaustion in 84.5% (1204/1425) and clinically disengagement in 91.1% (1298/1425), and 77.3% (1102/1425) met the score criteria for both the exhaustion and disengagement subscales for burnout. Burnout rate was significantly increased in the group …
OLBI results indicate clinically exhaustion in 84.5% (1204/1425) and clinically disengagement in 91.1% (1298/1425), and 77.3% (1102/1425) me …
Boston biorepository, recruitment and integrative network (BBRAIN): A resource for the Gulf War Illness scientific community.
Keating D, Zundel CG, Abreu M, Krengel M, Aenlle K, Nichols MD, Toomey R, Chao LL, Golier J, Abdullah L, Quinn E, Heeren T, Groh JR, Koo BB, Killiany R, Loggia ML, Younger J, Baraniuk J, Janulewicz P, Ajama J, Quay M, Baas PW, Qiang L, Conboy L, Kokkotou E, O'Callaghan JP, Steele L, Klimas N, Sullivan K. Keating D, et al. Life Sci. 2021 Nov 1;284:119903. doi: 10.1016/j.lfs.2021.119903. Epub 2021 Aug 26. Life Sci. 2021. PMID: 34453948 Free PMC article.
AIMS: Gulf War Illness (GWI), a chronic debilitating disorder characterized by fatigue, joint pain, cognitive, gastrointestinal, respiratory, and skin problems, is currently diagnosed by self-reported symptoms. ...They will be made available for data mining by the B …
AIMS: Gulf War Illness (GWI), a chronic debilitating disorder characterized by fatigue, joint pain, cognitive, gastrointestina …
"it's a medical condition you need to support as much as possible": a qualitative analysis of teachers' experiences of chronic fatigue syndrome / myalgic encephalomyelitis (CFS/ME).
Brigden A, Shaw A, Crawley E. Brigden A, et al. BMC Pediatr. 2021 Jan 4;21(1):6. doi: 10.1186/s12887-020-02461-7. BMC Pediatr. 2021. PMID: 33397331 Free PMC article.
CFS/ME is a complex and disabling condition, and there is little guidance on how primary school teachers can support younger children with this condition. To improve care, it is important to understand what these children need in the school setting, and the barriers and fa …
CFS/ME is a complex and disabling condition, and there is little guidance on how primary school teachers can support younger children …
Sexual dysfunction is prevalent in female lymphoma survivors after autologous stem-cell transplantation and is associated with younger age, chronic fatigue, and mental distress.
Bersvendsen HS, Haugnes HS, Dahl AA, Fagerli UM, Fluge Ø, Holte H, Wilsgaard T, Smeland KB, Kiserud CE. Bersvendsen HS, et al. Bone Marrow Transplant. 2021 Apr;56(4):968-970. doi: 10.1038/s41409-020-01098-5. Epub 2020 Nov 3. Bone Marrow Transplant. 2021. PMID: 33139869
Tiredness in relation to sexual activity was associated with younger age, chronic fatigue and mental distress. Sexual inactivity due to personal issues was more frequent and among those sexually active, a higher rate of sexual dysfunction exists among auto-SC …
Tiredness in relation to sexual activity was associated with younger age, chronic fatigue and mental distress. Sexual i …
Chronic fatigue syndrome/myalgic encephalomyelitis in children aged 5 to 11 years: A qualitative study.
Brigden A, Shaw A, Anderson E, Crawley E. Brigden A, et al. Clin Child Psychol Psychiatry. 2021 Jan;26(1):18-32. doi: 10.1177/1359104520964528. Epub 2020 Oct 22. Clin Child Psychol Psychiatry. 2021. PMID: 33092395 Free PMC article.
Treatments for paediatric chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME) have not been designed or evaluated for younger children (5-11-years). ...Twenty-two participants were interviewed; eight parents, two children (aged nine and ten) and six p …
Treatments for paediatric chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME) have not been designed or evaluated for …
"The child's got a complete circle around him". The care of younger children (5-11 years) with CFS/ME. A qualitative study comparing families', teachers' and clinicians' perspectives'.
Brigden A, Shaw A, Barnes R, Anderson E, Crawley E. Brigden A, et al. Health Soc Care Community. 2020 Nov;28(6):2179-2189. doi: 10.1111/hsc.13029. Epub 2020 Jun 9. Health Soc Care Community. 2020. PMID: 32519359
Our aim was to address this gap by examining how the care of children (aged 5-11 years) with Chronic Fatigue Syndrome/ Myalgic Encephalomyelitis (CFS/ME) is shared across home, education and health settings, in order to generate recommendations for integrating care. …
Our aim was to address this gap by examining how the care of children (aged 5-11 years) with Chronic Fatigue Syndrome/ Myalgic …
Prediction of long-term outcome after cognitive behavioral therapy for chronic fatigue syndrome.
Janse A, Bleijenberg G, Knoop H. Janse A, et al. J Psychosom Res. 2019 Jun;121:93-99. doi: 10.1016/j.jpsychores.2019.03.017. Epub 2019 Mar 19. J Psychosom Res. 2019. PMID: 31006534
Fatigue scores within normal limits at follow-up was predicted by lower fatigue severity and lower levels of frustration in response to fatigue, both assessed directly post-treatment. Better physical functioning at follow-up was predicted by higher sense of c
Fatigue scores within normal limits at follow-up was predicted by lower fatigue severity and lower levels of frustration in re
Fatigue following radiation therapy in nasopharyngeal cancer survivors: A dosimetric analysis incorporating patient report and observer rating.
MD Anderson Head Neck Cancer Symptom Working Group. MD Anderson Head Neck Cancer Symptom Working Group. Radiother Oncol. 2019 Apr;133:35-42. doi: 10.1016/j.radonc.2018.12.023. Epub 2019 Jan 14. Radiother Oncol. 2019. PMID: 30935579 Free PMC article.
Recursive partitioning analysis (RPA) was used to identify dose-volume effects associated with chronic fatigue. RESULTS: 56 pts formed the cohort. Thirty patients (54%) reported any fatigue per MDASI-HN-F. ...Dmax and Dmean of the PG were significantly higher …
Recursive partitioning analysis (RPA) was used to identify dose-volume effects associated with chronic fatigue. RESULTS: 56 pt …
Evidence of widespread metabolite abnormalities in Myalgic encephalomyelitis/chronic fatigue syndrome: assessment with whole-brain magnetic resonance spectroscopy.
Mueller C, Lin JC, Sheriff S, Maudsley AA, Younger JW. Mueller C, et al. Brain Imaging Behav. 2020 Apr;14(2):562-572. doi: 10.1007/s11682-018-0029-4. Brain Imaging Behav. 2020. PMID: 30617782 Free PMC article.
Previous neuroimaging studies have detected markers of neuroinflammation in patients with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS). ...We report metabolite and temperature abnormalities in ME/CFS patients in widely distributed regions. Our …
Previous neuroimaging studies have detected markers of neuroinflammation in patients with Myalgic Encephalomyelitis/Chronic
School Nurses Can Improve the Lives of Students With Myalgic Encephalomyelitis/Chronic Fatigue Syndrome.
Friedman KJ, Mattey B, Newton F. Friedman KJ, et al. NASN Sch Nurse. 2018 Nov;33(6):372-379. doi: 10.1177/1942602X18795299. Epub 2018 Sep 15. NASN Sch Nurse. 2018. PMID: 30222036
Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a chronic illness that is defined and diagnosed by its symptoms: extreme fatigue made worse by physical and mental activity, pain and decreased mental stamina, among others. ...The debilita …
Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a chronic illness that is defined and diagnosed by its s …
Cytokine signature associated with disease severity in chronic fatigue syndrome patients.
Montoya JG, Holmes TH, Anderson JN, Maecker HT, Rosenberg-Hasson Y, Valencia IJ, Chu L, Younger JW, Tato CM, Davis MM. Montoya JG, et al. Proc Natl Acad Sci U S A. 2017 Aug 22;114(34):E7150-E7158. doi: 10.1073/pnas.1710519114. Epub 2017 Jul 31. Proc Natl Acad Sci U S A. 2017. PMID: 28760971 Free PMC article.
Although some signs of inflammation have been reported previously in patients with myalgic encephalomyelitis or chronic fatigue syndrome (ME/CFS), the data are limited and contradictory. ...To determine whether a signature of serum cytokines could be associated with …
Although some signs of inflammation have been reported previously in patients with myalgic encephalomyelitis or chronic fatigue
Prevalence of and risk factors for severe cognitive and sleep symptoms in ME/CFS and MS.
Jain V, Arunkumar A, Kingdon C, Lacerda E, Nacul L. Jain V, et al. BMC Neurol. 2017 Jun 20;17(1):117. doi: 10.1186/s12883-017-0896-0. BMC Neurol. 2017. PMID: 28633629 Free PMC article.
BACKGROUND: There are considerable phenotypic and neuroimmune overlaps between myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) and multiple sclerosis (MS). While the precise aetiologies of both MS and ME/CFS are unclear, evidence suggests that deteriorat …
BACKGROUND: There are considerable phenotypic and neuroimmune overlaps between myalgic encephalomyelitis/chronic fatigue syndr …
Comorbidity in Chronic Fatigue Syndrome/Myalgic Encephalomyelitis: A Nationwide Population-Based Cohort Study.
Castro-Marrero J, Faro M, Aliste L, Sáez-Francàs N, Calvo N, Martínez-Martínez A, de Sevilla TF, Alegre J. Castro-Marrero J, et al. Psychosomatics. 2017 Sep-Oct;58(5):533-543. doi: 10.1016/j.psym.2017.04.010. Epub 2017 Apr 21. Psychosomatics. 2017. PMID: 28596045
BACKGROUND: Previous studies have shown evidence of comorbid conditions in chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME). OBJECTIVE: To estimate the prevalence of comorbidities and assess their associations using a nationwide population-based database …
BACKGROUND: Previous studies have shown evidence of comorbid conditions in chronic fatigue syndrome/myalgic encephalomyelitis …
Postural orthostatic tachycardia is not a useful diagnostic marker for chronic fatigue syndrome.
Roerink ME, Lenders JW, Schmits IC, Pistorius AM, Smit JW, Knoop H, van der Meer JW. Roerink ME, et al. J Intern Med. 2017 Feb;281(2):179-188. doi: 10.1111/joim.12564. Epub 2016 Oct 2. J Intern Med. 2017. PMID: 27696568 Free article.
BACKGROUND: Postural orthostatic tachycardia syndrome (POTS) is considered a diagnostic marker for chronic fatigue syndrome (CFS). OBJECTIVES: The aims of this study were to (i) compare POTS prevalence in a CFS cohort with fatigued patients not meeting CFS cr …
BACKGROUND: Postural orthostatic tachycardia syndrome (POTS) is considered a diagnostic marker for chronic fatigue syndrome (C …
Illness progression in chronic fatigue syndrome: a shifting immune baseline.
Russell L, Broderick G, Taylor R, Fernandes H, Harvey J, Barnes Z, Smylie A, Collado F, Balbin EG, Katz BZ, Klimas NG, Fletcher MA. Russell L, et al. BMC Immunol. 2016 Mar 10;17:3. doi: 10.1186/s12865-016-0142-3. BMC Immunol. 2016. PMID: 26965484 Free PMC article.
BACKGROUND: Validation of biomarkers for myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) across data sets has proven disappointing. ...METHODS: Cytokine expression collected at rest across multiple studies for female ME/CFS subjects (i) 18 years or yo
BACKGROUND: Validation of biomarkers for myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) across data sets has prov …
Chronic fatigue syndrome (CFS) or myalgic encephalomyelitis (ME) is different in children compared to in adults: a study of UK and Dutch clinical cohorts.
Collin SM, Nuevo R, van de Putte EM, Nijhof SL, Crawley E. Collin SM, et al. BMJ Open. 2015 Oct 28;5(10):e008830. doi: 10.1136/bmjopen-2015-008830. BMJ Open. 2015. PMID: 26510728 Free PMC article. Clinical Trial.
OBJECTIVE: To investigate differences between young children, adolescents and adults with chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME). STUDY DESIGN: Comparison of clinical cohorts from 8 paediatric and 27 adult CFS/ME services in the UK and a paediat …
OBJECTIVE: To investigate differences between young children, adolescents and adults with chronic fatigue syndrome/myalgic enc …
Evidence for abnormal cytokine expression in Gulf War Illness: A preliminary analysis of daily immune monitoring data.
Parkitny L, Middleton S, Baker K, Younger J. Parkitny L, et al. BMC Immunol. 2015 Sep 30;16:57. doi: 10.1186/s12865-015-0122-z. BMC Immunol. 2015. PMID: 26420016 Free PMC article.
BACKGROUND: Gulf War Illness (GWI) is a clinically heterogeneous chronic condition that affects many veterans of the 1990-1991 Persian Gulf War. One of the most prevalent and debilitating symptoms of GWI is abnormal fatigue. The mechanisms underlying GWI generally, …
BACKGROUND: Gulf War Illness (GWI) is a clinically heterogeneous chronic condition that affects many veterans of the 1990-1991 Persia …
Increased risk of organic erectile dysfunction in patients with chronic fatigue syndrome: a nationwide population-based cohort study.
Chao CH, Chen HJ, Wang HY, Li TC, Kao CH. Chao CH, et al. Andrology. 2015 Jul;3(4):666-71. doi: 10.1111/andr.12052. Andrology. 2015. PMID: 26198797 Free article.
Chronic fatigue syndrome (CFS) is a complex disorder characterized by profound and persistent fatigue and several comorbidities. ...We identified 2156 male patients who were newly diagnosed with CFS between January 1, 2003 and December 31, 2006. After excludi
Chronic fatigue syndrome (CFS) is a complex disorder characterized by profound and persistent fatigue and several comor
Intravenous immunoglobulin for postpolio syndrome: a systematic review and meta-analysis.
Huang YH, Chen HC, Huang KW, Chen PC, Hu CJ, Tsai CP, Tam KW, Kuan YC. Huang YH, et al. BMC Neurol. 2015 Mar 22;15:39. doi: 10.1186/s12883-015-0301-9. BMC Neurol. 2015. PMID: 25886512 Free PMC article. Review.
Moreover, one prospective study reported significant improvement on SF-36, particularly in patients aged younger than 65 years, those with paresis of the lower limbs, and high pain intensity. ...However, a potential effect in younger patients with lower limbs weakne …
Moreover, one prospective study reported significant improvement on SF-36, particularly in patients aged younger than 65 years, those …
Fatigue in child chronic health conditions: a systematic review of assessment instruments.
Crichton A, Knight S, Oakley E, Babl FE, Anderson V. Crichton A, et al. Pediatrics. 2015 Apr;135(4):e1015-31. doi: 10.1542/peds.2014-2440. Epub 2015 Mar 23. Pediatrics. 2015. PMID: 25802352 Review.
Fatigue was assessed in over 14 health conditions, most commonly in children with cancer and chronic fatigue syndrome. ...Further evidence is required for assessment of fatigue in younger children, and children with particular health conditions.
Fatigue was assessed in over 14 health conditions, most commonly in children with cancer and chronic fatigue syndrome.
Early menopause and other gynecologic risk indicators for chronic fatigue syndrome in women.
Boneva RS, Lin JM, Unger ER. Boneva RS, et al. Menopause. 2015 Aug;22(8):826-34. doi: 10.1097/GME.0000000000000411. Menopause. 2015. PMID: 25647777 Free PMC article.
OBJECTIVE: This study aims to examine whether gynecologic conditions are associated with chronic fatigue syndrome (CFS). METHODS: This study includes a subset of 157 women from a population-based case-control study in Georgia, United States, conducted in 2004-2009. …
OBJECTIVE: This study aims to examine whether gynecologic conditions are associated with chronic fatigue syndrome (CFS). METHO …
Longitudinal follow-up of employment status in patients with chronic fatigue syndrome after mononucleosis.
Nyland M, Naess H, Birkeland JS, Nyland H. Nyland M, et al. BMJ Open. 2014 Nov 26;4(11):e005798. doi: 10.1136/bmjopen-2014-005798. BMJ Open. 2014. PMID: 25428629 Free PMC article.
OBJECTIVE: To examine the effect of early clinical and demographic factors on occupational outcome, return to work or awarded permanent disability pension in young patients with chronic fatigue syndrome (CFS). DESIGN: Longitudinal cohort study. ...PRIMARY AND SECOND …
OBJECTIVE: To examine the effect of early clinical and demographic factors on occupational outcome, return to work or awarded permanent disa …
A control systems engineering approach for adaptive behavioral interventions: illustration with a fibromyalgia intervention.
Deshpande S, Rivera DE, Younger JW, Nandola NN. Deshpande S, et al. Transl Behav Med. 2014 Sep;4(3):275-89. doi: 10.1007/s13142-014-0282-z. Transl Behav Med. 2014. PMID: 25264467 Free PMC article.
The term adaptive intervention has been used in behavioral medicine to describe operationalized and individually tailored strategies for prevention and treatment of chronic, relapsing disorders. Control systems engineering offers an attractive means for designing and imple …
The term adaptive intervention has been used in behavioral medicine to describe operationalized and individually tailored strategies for pre …
An unusual presentation of Kikuchi-Fujimoto disease.
Van den Bergh M, Bauer FA, Posteraro AF, Thumma S, Dasanu CA. Van den Bergh M, et al. Conn Med. 2014 Apr;78(4):225-8. Conn Med. 2014. PMID: 24830120
This condition is most commonly encountered in Asian and Caucasian females of childbearing age who usually present with cervical lymphadenopathy and fever. Though rarely, KFD has been described in younger African-American females as well. It often mimics more serious condi …
This condition is most commonly encountered in Asian and Caucasian females of childbearing age who usually present with cervical lymphadenop …
Orthostatic intolerance and chronic fatigue syndrome--possible related conditions.
Chirilă EL, Postolache P. Chirilă EL, et al. Rev Med Chir Soc Med Nat Iasi. 2013 Apr-Jun;117(2):388-93. Rev Med Chir Soc Med Nat Iasi. 2013. PMID: 24340521
The connection between orthostatic intolerance and chronic fatigue syndrome was first introduced in 1995. It was demonstrated that many patients with chronic fatigue syndrome also had some form of orthostatic intolerance. ...Although these conditions a …
The connection between orthostatic intolerance and chronic fatigue syndrome was first introduced in 1995. It was demonstrated …
Comorbidity of postural orthostatic tachycardia syndrome and chronic fatigue syndrome in an Australian cohort.
Reynolds GK, Lewis DP, Richardson AM, Lidbury BA. Reynolds GK, et al. J Intern Med. 2014 Apr;275(4):409-17. doi: 10.1111/joim.12161. Epub 2013 Nov 29. J Intern Med. 2014. PMID: 24206536 Free article.
OBJECTIVE: Patients with chronic fatigue syndrome (CFS) are frequently diagnosed with comorbid postural orthostatic tachycardia syndrome (POTS), suggesting a shared pathogenesis. ...CONCLUSIONS: Haemodynamic and demographic differences between CFS-POTS and CFS-only …
OBJECTIVE: Patients with chronic fatigue syndrome (CFS) are frequently diagnosed with comorbid postural orthostatic tachycardi …
Early-life hygiene-related factors affect risk of central nervous system demyelination and asthma differentially.
Hughes AM, Lucas RM, McMichael AJ, Dwyer T, Pender MP, van der Mei I, Taylor BV, Valery P, Chapman C, Coulthard A, Dear K, Kilpatrick TJ, Williams D, Ponsonby AL. Hughes AM, et al. Clin Exp Immunol. 2013 Jun;172(3):466-74. doi: 10.1111/cei.12077. Clin Exp Immunol. 2013. PMID: 23600835 Free PMC article.
FCD cases did not differ from controls with regard to personal or family history of allergy, but had a greater likelihood of chronic fatigue syndrome [odds ratio (OR) = 3.11; 95% confidence interval (CI) 1.11, 8.71]. Having any younger siblings showed reduced …
FCD cases did not differ from controls with regard to personal or family history of allergy, but had a greater likelihood of chronic
Daily cytokine fluctuations, driven by leptin, are associated with fatigue severity in chronic fatigue syndrome: evidence of inflammatory pathology.
Stringer EA, Baker KS, Carroll IR, Montoya JG, Chu L, Maecker HT, Younger JW. Stringer EA, et al. J Transl Med. 2013 Apr 9;11:93. doi: 10.1186/1479-5876-11-93. J Transl Med. 2013. PMID: 23570606 Free PMC article.
BACKGROUND: Chronic fatigue syndrome (CFS) is a debilitating disorder characterized by persistent fatigue that is not alleviated by rest. ...Single time-point approaches potentially overlook important features of CFS, such as fluctuations in fatigue se …
BACKGROUND: Chronic fatigue syndrome (CFS) is a debilitating disorder characterized by persistent fatigue that is not a …
Is chronic fatigue syndrome in older patients a different disease? -- a clinical cohort study.
Lewis I, Pairman J, Spickett G, Newton JL. Lewis I, et al. Eur J Clin Invest. 2013 Mar;43(3):302-8. doi: 10.1111/eci.12046. Epub 2013 Feb 9. Eur J Clin Invest. 2013. PMID: 23397955
BACKGROUND: Chronic fatigue syndrome (CFS) is a disabling disorder characterised by persistent fatigue with a typical age of diagnosis of 35-50 years. ...RESULTS: Chronic fatigue syndrome can present for the first time in an older population. .. …
BACKGROUND: Chronic fatigue syndrome (CFS) is a disabling disorder characterised by persistent fatigue with a typical a …
Clinical characteristics of a novel subgroup of chronic fatigue syndrome patients with postural orthostatic tachycardia syndrome.
Lewis I, Pairman J, Spickett G, Newton JL. Lewis I, et al. J Intern Med. 2013 May;273(5):501-10. doi: 10.1111/joim.12022. Epub 2013 Jan 7. J Intern Med. 2013. PMID: 23206180 Free article.

OBJECTIVES: A significant proportion of patients with chronic fatigue syndrome (CFS) also have postural orthostatic tachycardia syndrome (POTS). ...RESULTS: CFS patients with POTS (13%, n = 24) were younger (29 12 vs. 42 13 years, P < 0.0001), less fati

OBJECTIVES: A significant proportion of patients with chronic fatigue syndrome (CFS) also have postural orthostatic tachycardi …
Functional impairment in chronic fatigue syndrome, fibromyalgia, and multiple chemical sensitivity.
Lavergne MR, Cole DC, Kerr K, Marshall LM. Lavergne MR, et al. Can Fam Physician. 2010 Feb;56(2):e57-65. Can Fam Physician. 2010. PMID: 20154232 Free PMC article.
OBJECTIVE: To characterize patients diagnosed with multiple chemical sensitivity (MCS), chronic fatigue syndrome (CFS), or fibromyalgia (FM), to compare their level of function with Canadian population average values, and to assess factors associated with function. …
OBJECTIVE: To characterize patients diagnosed with multiple chemical sensitivity (MCS), chronic fatigue syndrome (CFS), or fib …
Coenzyme Q10 deficiency in myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is related to fatigue, autonomic and neurocognitive symptoms and is another risk factor explaining the early mortality in ME/CFS due to cardiovascular disorder.
Maes M, Mihaylova I, Kubera M, Uytterhoeven M, Vrydags N, Bosmans E. Maes M, et al. Neuro Endocrinol Lett. 2009;30(4):470-6. Neuro Endocrinol Lett. 2009. PMID: 20010505
INTRODUCTION: Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a medical illness characterized by disorders in inflammatory and oxidative and nitrosative (IO&NS) pathways. ...The findings that lower CoQ10 is an independent predictor of chronic
INTRODUCTION: Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a medical illness characterized by disorders in i …
Allodynia in migraine: association with comorbid pain conditions.
Tietjen GE, Brandes JL, Peterlin BL, Eloff A, Dafer RM, Stein MR, Drexler E, Martin VT, Hutchinson S, Aurora SK, Recober A, Herial NA, Utley C, White L, Khuder SA. Tietjen GE, et al. Headache. 2009 Oct;49(9):1333-44. doi: 10.1111/j.1526-4610.2009.01521.x. Headache. 2009. PMID: 19788473
BACKGROUND: Cutaneous allodynia (CA) in migraine is a clinical manifestation of central nervous system sensitization. Several chronic pain syndromes and mood disorders are comorbid with migraine. ...The prevalence of self-reported physician diagnosis of comorbid pain condi …
BACKGROUND: Cutaneous allodynia (CA) in migraine is a clinical manifestation of central nervous system sensitization. Several chronic
Cardiac function fluctuates during exacerbation and remission in young adults with chronic fatigue syndrome and "small heart".
Miwa K, Fujita M. Miwa K, et al. J Cardiol. 2009 Aug;54(1):29-35. doi: 10.1016/j.jjcc.2009.02.008. Epub 2009 Mar 28. J Cardiol. 2009. PMID: 19632517 Free article.
BACKGROUND: "Small heart syndrome", previously referred to as so-called "neurocirculatory asthenia" associated with a small heart shadow on the chest roentgenogram, is characterized by weakness or fatigue even after mild exertion, palpitation, dyspnea, and fainting, many o …
BACKGROUND: "Small heart syndrome", previously referred to as so-called "neurocirculatory asthenia" associated with a small heart shadow on …
Anxiety in children with CFS/ME.
Crawley E, Hunt L, Stallard P. Crawley E, et al. Eur Child Adolesc Psychiatry. 2009 Nov;18(11):683-9. doi: 10.1007/s00787-009-0029-4. Epub 2009 May 19. Eur Child Adolesc Psychiatry. 2009. PMID: 19452195
Anxiety symptoms are commonly described in children with chronic fatigue syndrome or myalgic encephalopathy (CFS/ME) but to date there has been little information on the type of anxiety children experience or the relationship between anxiety and school attendance, d …
Anxiety symptoms are commonly described in children with chronic fatigue syndrome or myalgic encephalopathy (CFS/ME) but to da …
Normalization of leaky gut in chronic fatigue syndrome (CFS) is accompanied by a clinical improvement: effects of age, duration of illness and the translocation of LPS from gram-negative bacteria.
Maes M, Leunis JC. Maes M, et al. Neuro Endocrinol Lett. 2008 Dec;29(6):902-10. Neuro Endocrinol Lett. 2008. PMID: 19112401
BACKGROUND: There is now evidence that an increased translocation of LPS from gram negative bacteria with subsequent gut-derived inflammation, i.e. induction of systemic inflammation and oxidative & nitrosative stress (IO&NS), is a new pathway in chronic fatigue
BACKGROUND: There is now evidence that an increased translocation of LPS from gram negative bacteria with subsequent gut-derived inflammatio …
Factors associated with depression among individuals with chronic fatigue syndrome: findings from a nationally representative survey.
Fuller-Thomson E, Nimigon J. Fuller-Thomson E, et al. Fam Pract. 2008 Dec;25(6):414-22. doi: 10.1093/fampra/cmn064. Epub 2008 Oct 3. Fam Pract. 2008. PMID: 18836094
OBJECTIVES: Most previous research regarding chronic fatigue syndrome (CFS) and depression has relied on clinical samples. ...In the logistic regression analyses, the odds of depression among individuals with CFS were higher for females, younger respondents, …
OBJECTIVES: Most previous research regarding chronic fatigue syndrome (CFS) and depression has relied on clinical samples. ... …
Chronic fatigue syndrome in children aged 11 years old and younger.
Davies S, Crawley E. Davies S, et al. Arch Dis Child. 2008 May;93(5):419-21. doi: 10.1136/adc.2007.126649. Epub 2008 Jan 11. Arch Dis Child. 2008. PMID: 18192312
Children in primary school can be very disabled by chronic fatigue syndrome or ME (CFS/ME). The clinical presentation in this age group (under 12 years old) is almost identical to that in older children. ...Children under 12 were very disabled with mean school atten …
Children in primary school can be very disabled by chronic fatigue syndrome or ME (CFS/ME). The clinical presentation in this …
Causes of death among patients with chronic fatigue syndrome.
Jason LA, Corradi K, Gress S, Williams S, Torres-Harding S. Jason LA, et al. Health Care Women Int. 2006 Aug;27(7):615-26. doi: 10.1080/07399330600803766. Health Care Women Int. 2006. PMID: 16844674
Chronic fatigue syndrome (CFS) is a debilitating illness affecting thousands of individuals. ...The mean age of those who died from cancer and suicide was 47.8 and 39.3 years, respectively, which is considerably younger than those who died from cancer and sui
Chronic fatigue syndrome (CFS) is a debilitating illness affecting thousands of individuals. ...The mean age of those who died
Chronic fatigue syndrome in children: a cross sectional survey.
Patel MX, Smith DG, Chalder T, Wessely S. Patel MX, et al. Arch Dis Child. 2003 Oct;88(10):894-8. doi: 10.1136/adc.88.10.894. Arch Dis Child. 2003. PMID: 14500310 Free PMC article.
BACKGROUND: Chronic fatigue syndrome (CFS) in children is a controversial diagnosis with unclear aetiology, ill defined but likely increasing incidence, and debatable clinical management options. ...Some prognostic indicators for adults did not readily transfer to t …
BACKGROUND: Chronic fatigue syndrome (CFS) in children is a controversial diagnosis with unclear aetiology, ill defined but li …
What is chronic fatigue syndrome? Heterogeneity within an international multicentre study.
Wilson A, Hickie I, Hadzi-Pavlovic D, Wakefield D, Parker G, Straus SE, Dale J, McCluskey D, Hinds G, Brickman A, Goldenberg D, Demitrack M, Blakely T, Wessely S, Sharpe M, Lloyd A. Wilson A, et al. Aust N Z J Psychiatry. 2001 Aug;35(4):520-7. doi: 10.1046/j.1440-1614.2001.00888.x. Aust N Z J Psychiatry. 2001. PMID: 11531735
OBJECTIVE: We sought to compare the characteristics of patients presenting with chronic fatigue (CF) and related syndromes in eight international centres and to subclassify these subjects based on symptom profiles. ...Overall, the subjects had a high rate of reporti …
OBJECTIVE: We sought to compare the characteristics of patients presenting with chronic fatigue (CF) and related syndromes in …
Chronic fatigue syndrome in private practice psychiatry: family history of physical and mental health.
Endicott NA. Endicott NA. J Psychosom Res. 1999 Oct;47(4):343-54. doi: 10.1016/s0022-3999(99)00013-6. J Psychosom Res. 1999. PMID: 10616228
Forty-five psychiatric patients with chronic fatigue syndrome (CFS) were compared, using the case-control method, to two control groups selected from the same practice and matched on age, gender, and psychiatric diagnosis. ...The reported family history of physical …
Forty-five psychiatric patients with chronic fatigue syndrome (CFS) were compared, using the case-control method, to two contr …
Periodic K-alpha sleep EEG activity and periodic limb movements during sleep: comparisons of clinical features and sleep parameters.
MacFarlane JG, Shahal B, Mously C, Moldofsky H. MacFarlane JG, et al. Sleep. 1996 Apr;19(3):200-4. doi: 10.1093/sleep/19.3.200. Sleep. 1996. PMID: 8723376
Sleep parameters and somatic symptoms of 30 patients with K-alpha were compared with 30 patients with PLMS. The periodic K-alpha group was predominantly female, younger, exhibiting more slow-wave sleep, gastrointestinal symptoms and muscular complaints and fewer movement a …
Sleep parameters and somatic symptoms of 30 patients with K-alpha were compared with 30 patients with PLMS. The periodic K-alpha group was p …
Repetitively negative changing T waves at 24-h electrocardiographic monitors in patients with the chronic fatigue syndrome. Left ventricular dysfunction in a cohort.
Lerner AM, Lawrie C, Dworkin HS. Lerner AM, et al. Chest. 1993 Nov;104(5):1417-21. doi: 10.1378/chest.104.5.1417. Chest. 1993. PMID: 8222798
A total of 300 patients had undergone a 24-h Holter monitor. This group included 24 individuals with chronic fatigue syndrome (CFS). This population was restricted to individuals 50 years old or younger, and the patients with CFS are compared with the patient …
A total of 300 patients had undergone a 24-h Holter monitor. This group included 24 individuals with chronic fatigue syndrome …