Dysregulation of hydrogen sulfide producing enzyme cystathionine gamma-lyase contributes to maternal hypertension and placental abnormalities in preeclampsia.
Wang K, Ahmad S, Cai M, Rennie J, Fujisawa T, Crispi F, Baily J, Miller MR, Cudmore M, Hadoke PW, Wang R, Gratacós E, Buhimschi IA, Buhimschi CS, Ahmed A.
Wang K, et al.
Circulation. 2013 Jun 25;127(25):2514-22. doi: 10.1161/CIRCULATIONAHA.113.001631. Epub 2013 May 23.
Circulation. 2013.
PMID: 23704251
Hydrogen sulfide (H2S), a gaseous messenger produced mainly by cystathionine gamma-lyase (CSE), is a proangiogenic vasodilator. We hypothesized that a reduction in CSE activity may alter the angiogenic balance in preg …
Hydrogen sulfide (H2S), a gaseous messenger produced mainly by cystathionine gamma-lyase ( …