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Page 1
Advances of Zinc Signaling Studies in Prostate Cancer.
Li D, Stovall DB, Wang W, Sui G. Li D, et al. Int J Mol Sci. 2020 Jan 19;21(2):667. doi: 10.3390/ijms21020667. Int J Mol Sci. 2020. PMID: 31963946 Free PMC article. Review.
To date, several reviews have suggested antitumor activities of zinc and its potential as a therapeutic strategy of PCa. However, an overview about the role of zinc and its signaling in PCa is needed. Here, we review literature related to the content, …
To date, several reviews have suggested antitumor activities of zinc and its potential as a therapeutic strategy of PCa. Howev …
catena-Poly[[[aqua-(pyrazine-2-carboxamide-kappa(2)N(1),O)zinc]-mu-pyrazine-2-carboxamide-kappa(3)N(1),O:N(4)] dinitrate].
Shirvan SA, Haydari Dezfuli S. Shirvan SA, et al. Acta Crystallogr Sect E Struct Rep Online. 2012 May 1;68(Pt 5):m627-8. doi: 10.1107/S1600536812016017. Epub 2012 Apr 18. Acta Crystallogr Sect E Struct Rep Online. 2012. PMID: 22590125 Free PMC article.
In the crystal of the title compound, {[Zn(C(5)H(5)N(3)O)(2)(H(2)O)](NO(3))(2)}(n), the Zn(II) cation is N,O-chelated by two pyrazine-2-carboxamide (PCA) ligands and is further coordinated by one water mol-ecule and by one pyrazine-N atom from an adjacent PCA ligand …
In the crystal of the title compound, {[Zn(C(5)H(5)N(3)O)(2)(H(2)O)](NO(3))(2)}(n), the Zn(II) cation is N,O-chelated by two pyrazine-2-carb …
Deciphering the role of zinc homeostasis in the tumor microenvironment and prognosis of prostate cancer.
Guo T, Wang J, Meng X, Wang Y, Lou Y, Ma J, Xu S, Ni X, Jia Z, Jin L, Wang C, Chen Q, Li P, Huang Y, Ren S. Guo T, et al. Discov Oncol. 2024 Jun 4;15(1):207. doi: 10.1007/s12672-024-01006-z. Discov Oncol. 2024. PMID: 38833013 Free PMC article.
BACKGROUND: Dysregulation of zinc homeostasis is widely recognized as a hallmark feature of prostate cancer (PCa) based on the compelling clinical and experimental evidence. Nevertheless, the implications of zinc dyshomeostasis in PCa remains largely u …
BACKGROUND: Dysregulation of zinc homeostasis is widely recognized as a hallmark feature of prostate cancer (PCa) based on the …
Zinc Deficiency in Men Over 50 and Its Implications in Prostate Disorders.
Sauer AK, Vela H, Vela G, Stark P, Barrera-Juarez E, Grabrucker AM. Sauer AK, et al. Front Oncol. 2020 Aug 6;10:1293. doi: 10.3389/fonc.2020.01293. eCollection 2020. Front Oncol. 2020. PMID: 32850402 Free PMC article. Review.
In particular, we will review the etiology of benign prostate enlargement (BPH), its prevalence in men over 50, the likelihood of BPH becoming prostate cancer (PCa), and explain the relationship of zinc and apoptosis in the prostate cells and the implications for BP …
In particular, we will review the etiology of benign prostate enlargement (BPH), its prevalence in men over 50, the likelihood of BPH becomi …
Urinary Zinc Loss Identifies Prostate Cancer Patients.
Maddalone MG, Oderda M, Mengozzi G, Gesmundo I, Novelli F, Giovarelli M, Gontero P, Occhipinti S. Maddalone MG, et al. Cancers (Basel). 2022 Oct 28;14(21):5316. doi: 10.3390/cancers14215316. Cancers (Basel). 2022. PMID: 36358735 Free PMC article.
Prostate Cancer (PCa) is one of the most common malignancies in men worldwide, with 1.4 million diagnoses and 310,000 deaths in 2020. ...One of the most consistent characteristics of PCa is the marked decrease in zinc; hence the lost ability to accumulate and …
Prostate Cancer (PCa) is one of the most common malignancies in men worldwide, with 1.4 million diagnoses and 310,000 deaths in 2020. …
Gd-DOTA-G-NH(CH2)11CO-RSPAYYTAA-(CH2CH2O)8-R.
Zhang H. Zhang H. 2008 Dec 22 [updated 2009 Jan 14]. In: Molecular Imaging and Contrast Agent Database (MICAD) [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2004–2013. 2008 Dec 22 [updated 2009 Jan 14]. In: Molecular Imaging and Contrast Agent Database (MICAD) [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2004–2013. PMID: 20641204 Free Books & Documents. Review.
Matrix metalloproteinases (MMPs) are a family of zinc-dependent endopeptidases localized at the cell surface or in extracellular compartments (1). ...The active site of MMPs contains a catalytic domain coordinated by zinc to recognize motifs with a consensus sequenc …
Matrix metalloproteinases (MMPs) are a family of zinc-dependent endopeptidases localized at the cell surface or in extracellular comp …
Exposure to heavy metal elements may significantly increase serum prostate-specific antigen levels with overdosed dietary zinc.
Fang Y, Chen C, Chen X, Song J, Feng S, Li Z, Li Z, Xiong Y, Zhang Q, Su H, Liu H, Zhu G, Hu B, Wang W, Liu Z, Jiao K, Zhang C, Zhang F, Jiang K, He J, Sun Z, Yuan D, Chen W, Zhu J. Fang Y, et al. Ecotoxicol Environ Saf. 2024 Mar 1;272:116080. doi: 10.1016/j.ecoenv.2024.116080. Epub 2024 Feb 12. Ecotoxicol Environ Saf. 2024. PMID: 38350215 Free article.
BACKGROUND: Serum prostate-specific antigen (PSA) is a primary metric for diagnosis and prognosis of prostate cancer (PCa). Exposure to heavy metals, such as lead, cadmium, mercury, and zinc can impact PSA levels in PCa patients. ...CONCLUSIONS: With high-lev …
BACKGROUND: Serum prostate-specific antigen (PSA) is a primary metric for diagnosis and prognosis of prostate cancer (PCa). Exposure …
The Prevalence of Zinc Deficiency among Men with and without Prostate Cancer in Port Harcourt, Nigeria.
Amadi C, Aleme BM. Amadi C, et al. Nutr Cancer. 2020;72(6):1018-1025. doi: 10.1080/01635581.2019.1664600. Epub 2019 Sep 14. Nutr Cancer. 2020. PMID: 31522560
Prevalence of zinc deficiency among PCa and control groups was 69.1% and 21.8%, respectively. Zinc deficiency was more prevalent among the elderly PCa patients (n = 119; 78.3%) compared to elderly controls. Higher proportion (n = 136; 89.5%) of zinc …
Prevalence of zinc deficiency among PCa and control groups was 69.1% and 21.8%, respectively. Zinc deficiency was more …
Zinc and prostate cancer: a critical scientific, medical, and public interest issue (United States).
Costello LC, Franklin RB, Feng P, Tan M, Bagasra O. Costello LC, et al. Cancer Causes Control. 2005 Oct;16(8):901-15. doi: 10.1007/s10552-005-2367-y. Cancer Causes Control. 2005. PMID: 16132800 Review.
The overwhelming clinical and experimental evidence provides a compelling rational basis for the expectation and concept that prostate zinc accumulation is an important factor in the development and progression of prostate malignancy; and that zinc could be efficaci …
The overwhelming clinical and experimental evidence provides a compelling rational basis for the expectation and concept that prostate zi …
Matrix metalloproteinases targeting in prostate cancer.
Zhu S, He J, Yin L, Zhou J, Lian J, Ren Y, Zhang X, Yuan J, Wang G, Li X. Zhu S, et al. Urol Oncol. 2024 Sep;42(9):275-287. doi: 10.1016/j.urolonc.2024.05.002. Epub 2024 May 28. Urol Oncol. 2024. PMID: 38806387 Free article. Review.
Prostate cancer (PCa) is one of the most common tumors affecting men all over the world. PCa has brought a huge health burden to men around the world, especially for elderly men, but its pathogenesis is unclear. ...An important role in cancer invasion and metastasis …
Prostate cancer (PCa) is one of the most common tumors affecting men all over the world. PCa has brought a huge health burden …
602 results