Epigenetic aberrations and cancer

Mol Cancer. 2006 Nov 8:5:60. doi: 10.1186/1476-4598-5-60.

Abstract

The correlation between epigenetic aberrations and disease underscores the importance of epigenetic mechanisms. Here, we review recent findings regarding chromatin modifications and their relevance to cancer.

Publication types

  • Review

MeSH terms

  • Adenosine Triphosphate / metabolism
  • Animals
  • Chromatin / chemistry
  • Chromatin / metabolism*
  • DNA Methylation
  • Epigenesis, Genetic*
  • Gene Expression Regulation
  • Histones / metabolism
  • Humans
  • Mice
  • Neoplasms / genetics*
  • Nucleosomes / chemistry
  • RNA, Untranslated / physiology

Substances

  • Chromatin
  • Histones
  • Nucleosomes
  • RNA, Untranslated
  • Adenosine Triphosphate