The interfacial tension of lipid membranes composed of phosphatidylcholine (lecithin, PC)-valine (Val), phosphatidylcholine-isoleucine (Ile), phosphatidylcholine-tyrosine (Tyr), and phosphatidylcholine-phenylalanine (Phe) has been studied. The membrane components formed 1:1 complexes. The interfacial tension measurements were used to determine the membrane surface concentration A (3)(-1), the membrane interfacial tension γ(3), and the stability constant K.