Abstract
Analysis of Plasmodium falciparum isolates collected before, during, and after a 1999 malaria epidemic in Djibouti shows that, despite a high prevalence of resistance to chloroquine, the epidemic cannot be attributed to a sudden increase in drug resistance of local parasite populations.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Animals
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Antimalarials / therapeutic use*
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DNA, Protozoan / chemistry
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DNA, Protozoan / genetics
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Disease Outbreaks*
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Djibouti / epidemiology
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Drug Resistance / genetics
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Genetic Variation
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Haplotypes
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Humans
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Malaria, Falciparum / blood
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Malaria, Falciparum / drug therapy
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Malaria, Falciparum / epidemiology*
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Malaria, Falciparum / parasitology*
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Plasmodium falciparum / drug effects*
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Plasmodium falciparum / isolation & purification
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Point Mutation
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Polymerase Chain Reaction
Substances
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Antimalarials
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DNA, Protozoan