The mismatch repair and base excision repair pathways: an opportunity for individualized (personalized) sensitization of cancer therapy

Cancer Biol Ther. 2009 Jun;8(12):1164-6. doi: 10.4161/cbt.8.12.8750. Epub 2009 Jun 16.

Authors

Sean P Collins¹, Anatoly Dritschilo

Affiliation

¹ Departments of Radiation Medicine and Oncology, Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, Washington, DC, USA.

No abstract available

Publication types

Comment

MeSH terms

Base Pair Mismatch*
DNA Repair*
Endodeoxyribonucleases / genetics*
Endodeoxyribonucleases / metabolism*
Humans
Idoxuridine / pharmacology
Neoplasms / genetics*
Neoplasms / metabolism
Neoplasms / therapy*
Thymine DNA Glycosylase / metabolism

Substances

Endodeoxyribonucleases
MBD4 protein, human
Thymine DNA Glycosylase
Idoxuridine