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Synergistic effect of resveratrol and HSV-TK/GCV therapy on murine hepatoma cells.
Xiao J, Wang X, Wu Y, Zhao Q, Liu X, Zhang G, Zhao Z, Ning Y, Wang K, Tan Y, Du B. Xiao J, et al. Cancer Biol Ther. 2019;20(2):183-191. doi: 10.1080/15384047.2018.1523094. Epub 2018 Sep 26. Cancer Biol Ther. 2019. PMID: 30257140 Free PMC article.
Hypothetically, the resveratrol-induced upregulation of gap junctions may improve the bystander effect that HSV-TK/GCV has on hepatoma cells. ...The present results demonstrate that resveratrol can enhance the bystander effect exerted by the HSV-TK/GCV system by enh …
Hypothetically, the resveratrol-induced upregulation of gap junctions may improve the bystander effect that HSV-TK/GCV has on hepatom …
Natural polyphenols: potential in the prevention of sexually transmitted viral infections.
Date AA, Destache CJ. Date AA, et al. Drug Discov Today. 2016 Feb;21(2):333-41. doi: 10.1016/j.drudis.2015.10.019. Epub 2015 Nov 4. Drug Discov Today. 2016. PMID: 26546859 Review.
The review gives an account of various in vitro and in vivo studies carried out on epigallocatechin gallate, theaflavins (black tea polyphenols), resveratrol, genistein and curcumin to highlight their potential to prevent sexually transmitted infections caused by HIV (huma …
The review gives an account of various in vitro and in vivo studies carried out on epigallocatechin gallate, theaflavins (black tea polyphen …
Phytochemicals targeting JAK/STAT pathway in the treatment of rheumatoid arthritis: Is there a future?
Kour G, Choudhary R, Anjum S, Bhagat A, Bajaj BK, Ahmed Z. Kour G, et al. Biochem Pharmacol. 2022 Mar;197:114929. doi: 10.1016/j.bcp.2022.114929. Epub 2022 Jan 19. Biochem Pharmacol. 2022. PMID: 35065024 Review.
However, the discernible risks of thromboembolism, gastrointestinal (GIT) perforations, hepatotoxicity and serious infections including tuberculosis, herpes zoster associated with their administration cannot be overlooked. Furthermore, these are highly expensive which limi …
However, the discernible risks of thromboembolism, gastrointestinal (GIT) perforations, hepatotoxicity and serious infections including tube …
NF-κB-regulated, proinflammatory miRNAs in Alzheimer's disease.
Lukiw WJ. Lukiw WJ. Alzheimers Res Ther. 2012 Dec 6;4(6):47. doi: 10.1186/alzrt150. eCollection 2012. Alzheimers Res Ther. 2012. PMID: 23217212 Free PMC article. Review.
Quenching of NF-kappaB-sensitive inflammatory miRNA signaling using NF-kappaB-inhibitors such as the polyphenolic resveratrol analog trans-3,5,4'-trihydroxystilbene (CAY10512) may have some therapeutic value in reducing inflammatory neurodegeneration. Antagonism of NF-kapp …
Quenching of NF-kappaB-sensitive inflammatory miRNA signaling using NF-kappaB-inhibitors such as the polyphenolic resveratrol analog …
Resveratrol exhibits a strong cytotoxic activity in cultured cells and has an antiviral action against polyomavirus: potential clinical use.
Berardi V, Ricci F, Castelli M, Galati G, Risuleo G. Berardi V, et al. J Exp Clin Cancer Res. 2009 Jul 1;28(1):96. doi: 10.1186/1756-9966-28-96. J Exp Clin Cancer Res. 2009. PMID: 19570215 Free PMC article.
BACKGROUND: Resveratrol is a non flavonoid polyphenol compound present in many plants and fruits and, at especially high concentrations, in the grape berries of Vitis vinifera. ...In this work we assayed the bioactivity of resveratrol as antiproliferative and antivi …
BACKGROUND: Resveratrol is a non flavonoid polyphenol compound present in many plants and fruits and, at especially high concentratio …
Potent Inhibition of HIV-1 Replication in Resting CD4 T Cells by Resveratrol and Pterostilbene.
Chan CN, Trinité B, Levy DN. Chan CN, et al. Antimicrob Agents Chemother. 2017 Aug 24;61(9):e00408-17. doi: 10.1128/AAC.00408-17. Print 2017 Sep. Antimicrob Agents Chemother. 2017. PMID: 28652233 Free PMC article.
Resveratrol has been shown to inhibit the replication of several viruses, including herpes simplex viruses 1 and 2, papillomaviruses, severe acute respiratory syndrome virus, and influenza virus. ...These findings are consistent with the reported ability of resve …
Resveratrol has been shown to inhibit the replication of several viruses, including herpes simplex viruses 1 and 2, papillomav …
Inhibition of herpes simplex virus infection by oligomeric stilbenoids through ROS generation.
Chen X, Qiao H, Liu T, Yang Z, Xu L, Xu Y, Ge HM, Tan RX, Li E. Chen X, et al. Antiviral Res. 2012 Jul;95(1):30-6. doi: 10.1016/j.antiviral.2012.05.001. Epub 2012 May 11. Antiviral Res. 2012. PMID: 22584350
Stilbenoids including resveratrol contain the basic structural unit of 1,2-diphenylethylene. Naturally occurring stilbenoids have broad structural features due to oligomerization and modifications and some have demonstrated potent biological activities. ...In addition to t …
Stilbenoids including resveratrol contain the basic structural unit of 1,2-diphenylethylene. Naturally occurring stilbenoids have bro …
Transcriptome analysis of the response of four immune related organs of tilapia (Oreochromis niloticus) to the addition of resveratrol in feed.
Ye W, Zheng Y, Sun Y, Li Q, Zhu H, Xu G. Ye W, et al. Fish Shellfish Immunol. 2023 Feb;133:108510. doi: 10.1016/j.fsi.2022.108510. Epub 2023 Jan 3. Fish Shellfish Immunol. 2023. PMID: 36608812
Resveratrol (RES) has been found to have immunological enhancement effects on Oreochromis niloticus. ...Kyoto encyclopedia of genes and genomes (KEGG) pathways associated with herpes simplex virus 1 infection, calcium signaling pathway, cell adhesion molecules, apop …
Resveratrol (RES) has been found to have immunological enhancement effects on Oreochromis niloticus. ...Kyoto encyclopedia of genes a …
Phytochemical add-on therapy to DMARDs therapy in rheumatoid arthritis: In vitro and in vivo bases, clinical evidence and future trends.
Kour G, Haq SA, Bajaj BK, Gupta PN, Ahmed Z. Kour G, et al. Pharmacol Res. 2021 Jul;169:105618. doi: 10.1016/j.phrs.2021.105618. Epub 2021 Apr 18. Pharmacol Res. 2021. PMID: 33878447 Review.
However, the long-term treatment in RA is associated with the risk of gastrointestinal, liver, pulmonary and renal toxicities and serious infections including latent tuberculosis, pneumococcus influenza, herpes zoster and hepatitis. These adverse effects sometimes lead to …
However, the long-term treatment in RA is associated with the risk of gastrointestinal, liver, pulmonary and renal toxicities and serious in …
Antiviral potential of phenolic compounds against HSV-1: In-vitro study.
Zangooie S, Ghanbari R, Jalilian FA, Mahmoudvand S, Teimoori A. Zangooie S, et al. Antivir Ther. 2024 Oct;29(5):13596535241271589. doi: 10.1177/13596535241271589. Antivir Ther. 2024. PMID: 39311585 Free article.
BACKGROUND: This in vitro study aimed to investigate the effect of several phenolic compounds, including doxorubicin, quercetin, and resveratrol, on HSV-1 infection. METHODS: The cytotoxicity of the drugs was assessed on Vero cells using the MTT assay. ...The anti-inflamma …
BACKGROUND: This in vitro study aimed to investigate the effect of several phenolic compounds, including doxorubicin, quercetin, and resv …