Repeatability of new optical biometer and agreement with 2 validated optical biometers, all based on SS-OCT

J Cataract Refract Surg. 2023 Jan 1;49(1):5-10. doi: 10.1097/j.jcrs.0000000000001023.


Purpose: To evaluate the repeatability of the measurements provided by a new optical biometer (EyeStar 900) based on swept-source optical coherence tomography (SS-OCT) and their agreement with the measurements given by 2 validated biometers based on the same technology, the IOLMaster 700 and Argos.

Setting: IRCCS G.B. Bietti Foundation, Rome, Italy.

Design: Prospective evaluation of diagnostic test.

Methods: In a series of unoperated eyes, 3 consecutive scans were acquired with the EyeStar 900, and 1 with the IOLMaster 700 and the Argos. The following biometry parameters were analyzed: axial length (AL), keratometry (K), corneal astigmatism, central corneal thickness, corneal diameter (CD), anterior chamber depth (ACD), lens thickness (LT), and lens tilting. Repeatability was assessed using test-retest variability, the coefficient of variation (CoV), and the intraclass correlation coefficient (ICC); agreement was based on the 95% limits of agreement.

Results: 56 eyes of 56 patients were analyzed. High repeatability was achieved for all measured parameters, as the CoV was <1% in most cases and ICC was >0.95 for all parameters. Good to high agreement was found among the measurements of the 3 optical biometers, although some statistically significant differences were detected between the EyeStar 900 and Argos (mean K, ACD, LT, and CD were higher with the Argos). The Argos measured a shorter AL in eyes >25 mm.

Conclusions: The new generation SS-OCT EyeStar 900 optical biometer produces highly repeatable measurements that are in good agreement with those provided by 2 previously validated instruments.

MeSH terms

  • Anterior Chamber / anatomy & histology
  • Anterior Chamber / diagnostic imaging
  • Axial Length, Eye* / anatomy & histology
  • Biometry / methods
  • Cornea / anatomy & histology
  • Humans
  • Interferometry
  • Prospective Studies
  • Reproducibility of Results
  • Tomography, Optical Coherence* / methods