Abstract
Recent advances have provided evidence that prostaglandin E2 mediates the generation of fever in response to interleukin-1 or lipopolysaccharide and have reinforced the similarities of signaling downstream of these two pyrogens.
MeSH terms
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Animals
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Body Temperature Regulation
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Cytokines / physiology
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Dinoprostone / physiology*
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Fever / physiopathology*
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Humans
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Interleukin-1
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Lipopolysaccharides
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Models, Biological
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Pyrogens
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Receptors, Prostaglandin E / physiology*
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Signal Transduction / physiology*
Substances
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Cytokines
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Interleukin-1
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Lipopolysaccharides
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Pyrogens
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Receptors, Prostaglandin E
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Dinoprostone