Abstract
Membrane peptidases are a multifunctional group of ectoenzymes that have been implicated in the control of growth and differentiation of many cellular systems. Here, using aminopeptidase N/CD13 as an example, Dagmar Riemann and colleagues discuss the role of cell-cell contact in peptidase regulation and the influence of peptidases on cellular functions.
Publication types
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Research Support, Non-U.S. Gov't
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Review
MeSH terms
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Adult
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Antigens, Neoplasm / immunology
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Antigens, Neoplasm / physiology
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CD13 Antigens / genetics
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CD13 Antigens / immunology
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CD13 Antigens / physiology*
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Cell Adhesion
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Cell Communication
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Child
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Chorionic Villi / enzymology
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Chorionic Villi / ultrastructure
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Coculture Techniques
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Enzyme Induction
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Extracellular Matrix / enzymology
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Gene Expression Regulation, Leukemic
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Hematopoietic Stem Cells / cytology
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Hematopoietic Stem Cells / enzymology
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Humans
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Immunophenotyping
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Inflammation / enzymology
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Inflammation / immunology
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Intestines / enzymology
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Intestines / ultrastructure
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Kidney Tubules / enzymology
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Kidney Tubules / ultrastructure
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Leukemia / classification
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Leukemia / enzymology
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Leukemia / immunology
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Lymphoma / classification
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Lymphoma / enzymology
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Lymphoma / immunology
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Microvilli / enzymology
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Monocytes / cytology
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Monocytes / enzymology
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Neoplasm Proteins / immunology
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Neoplasm Proteins / physiology
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Neoplasms / enzymology
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Neoplasms / immunology
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Organ Specificity
Substances
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Antigens, Neoplasm
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Neoplasm Proteins
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CD13 Antigens