Malignant trophoblastic disease following a twin pregnancy consisting of a complete hydatiform mole and a normal fetus and placenta. A case report

S Vandeginste; I B Vergote; M Hanssens; P Moerman; G Page; K Van Den Berghe; A Van Assche

Malignant trophoblastic disease following a twin pregnancy consisting of a complete hydatiform mole and a normal fetus and placenta. A case report

Eur J Gynaecol Oncol. 1999;20(2):105-7.

Authors

S Vandeginste¹, I B Vergote, M Hanssens, P Moerman, G Page, K Van Den Berghe, A Van Assche

Affiliation

¹ Department of Obstetrics and Gynaecology, University Hospitals Leuven, Belgium.

PMID: 10376424

Abstract

We report an unusual pregnancy with a complete hydatiform mole coexisting with a normal fetus and placenta. This report stresses the importance of a correct diagnosis and the dilemmas the clinician is faced with when managing such a case. Malignant trophoblastic disease occurs in 55% of complete hydatiform mole and fetus. Two-thirds require combination chemotherapy.

Publication types

Case Reports

MeSH terms

Abortifacient Agents, Nonsteroidal / therapeutic use
Abortion, Induced / methods
Adult
Antimetabolites, Antineoplastic / therapeutic use
Diagnosis, Differential
Female
Humans
Hydatidiform Mole, Invasive / diagnosis*
Hydatidiform Mole, Invasive / drug therapy
Methotrexate / therapeutic use
Misoprostol / therapeutic use
Pregnancy
Pregnancy, Multiple*
Trophoblastic Neoplasms / diagnosis
Twins
Uterine Neoplasms / diagnosis*
Uterine Neoplasms / drug therapy

Substances

Abortifacient Agents, Nonsteroidal
Antimetabolites, Antineoplastic
Misoprostol
Methotrexate