Dynamic contrast-enhanced MRI in the differentiation of breast tumors: user-defined versus semi-automated region-of-interest analysis

J Magn Reson Imaging. 1999 Dec;10(6):945-9. doi: 10.1002/(sici)1522-2586(199912)10:6<945::aid-jmri6>3.0.co;2-i.

Abstract

Dynamic contrast-enhanced MR mammography is an increasingly used method of evaluating breast pathology. The purpose of this study was to compare two semi-automated methods of region of interest (ROI) analysis with a user-defined method, in the discrimination of breast tumors using dynamic contrast-enhanced MRI. Results are presented from the retrospective analysis of 81 malignant and 36 benign breast lesions. The study demonstrates the importance of a consistent ROI strategy and also shows that semi-automated approaches offer a standardized method, which may improve the discrimination of primary breast tumors. J. Magn. Reson. Imaging 1999; 10:945-949.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adenocarcinoma / diagnosis
  • Adenocarcinoma, Mucinous / diagnosis
  • Adult
  • Aged
  • Aged, 80 and over
  • Breast / pathology
  • Breast Neoplasms / diagnosis*
  • Carcinoma in Situ / diagnosis
  • Carcinoma, Lobular / diagnosis
  • Carcinoma, Medullary / diagnosis
  • Contrast Media*
  • Diagnosis, Differential
  • Female
  • Fibroadenoma / diagnosis
  • Fibrocystic Breast Disease / diagnosis
  • Fibrosis
  • Follow-Up Studies
  • Humans
  • Image Enhancement / methods*
  • Image Processing, Computer-Assisted / methods*
  • Magnetic Resonance Imaging / methods*
  • Middle Aged
  • Neoplasm Invasiveness
  • Retrospective Studies
  • Sclerosis

Substances

  • Contrast Media