Isolation and structure of an untriakontapeptide with opiate activity from camel pituitary glands

Proc Natl Acad Sci U S A. 1976 Apr;73(4):1145-8. doi: 10.1073/pnas.73.4.1145.

Abstract

The isolation of an untriakontapeptide from camel pituitary extracts has been described. Its structure has been determined and shown to be identical to the sequence of carboxyl-terminal 31 amino acids of ovine beta-lipotropin. The peptide possesses very low lipotropic activity but significant opiate activity.

MeSH terms

  • Amino Acids / analysis
  • Animals
  • Binding, Competitive
  • Camelus
  • Lipid Metabolism
  • Morphine
  • Oligopeptides / analysis
  • Opium*
  • Peptides / analysis*
  • Peptides / isolation & purification
  • Peptides / metabolism
  • Pituitary Gland
  • Receptors, Drug
  • beta-Lipotropin / metabolism

Substances

  • Amino Acids
  • Oligopeptides
  • Peptides
  • Receptors, Drug
  • Morphine
  • Opium
  • beta-Lipotropin