Basal cell carcinomas in mice overexpressing Gli2 in skin

Nat Genet. 2000 Mar;24(3):216-7. doi: 10.1038/73417.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Animals
  • Carcinoma, Basal Cell / genetics*
  • Carcinoma, Basal Cell / metabolism
  • Carcinoma, Basal Cell / pathology
  • Cattle
  • Cell Transformation, Neoplastic / genetics*
  • Epidermis / metabolism
  • Gene Expression Regulation*
  • Gene Expression Regulation, Neoplastic
  • Genetic Predisposition to Disease
  • Hedgehog Proteins
  • Keratinocytes / metabolism
  • Keratins / genetics
  • Kruppel-Like Transcription Factors
  • Mice
  • Mice, Transgenic
  • Neoplasm Proteins / biosynthesis
  • Neoplasm Proteins / genetics
  • Neoplasms, Multiple Primary / genetics*
  • Neoplasms, Multiple Primary / metabolism
  • Promoter Regions, Genetic
  • Proteins / physiology*
  • RNA, Messenger / biosynthesis
  • RNA, Neoplasm / biosynthesis
  • Signal Transduction
  • Skin Neoplasms / genetics*
  • Skin Neoplasms / metabolism
  • Skin Neoplasms / pathology
  • Trans-Activators*
  • Transcription Factors / genetics*
  • Transcription Factors / physiology
  • Zinc Finger Protein Gli2

Substances

  • Gli2 protein, mouse
  • Hedgehog Proteins
  • Kruppel-Like Transcription Factors
  • Neoplasm Proteins
  • Proteins
  • RNA, Messenger
  • RNA, Neoplasm
  • Trans-Activators
  • Transcription Factors
  • Zinc Finger Protein Gli2
  • Keratins