The potential of a genome-substituted form Avrolata (AABBUU) as a genetic system in genomic and chromosome manipulations for gene transfer from the wild species Aegilops umbellulata Eig. (UU) to cultivated wheat was studied. It was shown that plants combining resistance to leaf brown rust with high productivity may be produced from this form by classical hybridization procedures. The resistance gene introduced to line R-12 is dominant and probably identical to the Lr9 gene. By N-banding, chromosome staining technique and gliadin electrophoresis, the structural changes in chromosomes 1A, 2A, 4B, 6B, 7B, 1D, and 2D of the resistant line R-12 were revealed.